KEGG   Canis lupus dingo (dingo): 112656209
Entry
112656209         CDS       T08371                                 
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X3
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
clud  Canis lupus dingo (dingo)
Pathway
clud00562  Inositol phosphate metabolism
clud01100  Metabolic pathways
clud01521  EGFR tyrosine kinase inhibitor resistance
clud04068  FoxO signaling pathway
clud04070  Phosphatidylinositol signaling system
clud04071  Sphingolipid signaling pathway
clud04115  p53 signaling pathway
clud04140  Autophagy - animal
clud04150  mTOR signaling pathway
clud04151  PI3K-Akt signaling pathway
clud04218  Cellular senescence
clud04510  Focal adhesion
clud04931  Insulin resistance
clud05165  Human papillomavirus infection
clud05166  Human T-cell leukemia virus 1 infection
clud05200  Pathways in cancer
clud05206  MicroRNAs in cancer
clud05208  Chemical carcinogenesis - reactive oxygen species
clud05213  Endometrial cancer
clud05214  Glioma
clud05215  Prostate cancer
clud05218  Melanoma
clud05222  Small cell lung cancer
clud05224  Breast cancer
clud05225  Hepatocellular carcinoma
clud05230  Central carbon metabolism in cancer
clud05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
clud05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:clud00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    112656209 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    112656209 (PTEN)
   04070 Phosphatidylinositol signaling system
    112656209 (PTEN)
   04071 Sphingolipid signaling pathway
    112656209 (PTEN)
   04151 PI3K-Akt signaling pathway
    112656209 (PTEN)
   04150 mTOR signaling pathway
    112656209 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112656209 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    112656209 (PTEN)
   04218 Cellular senescence
    112656209 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112656209 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112656209 (PTEN)
   05206 MicroRNAs in cancer
    112656209 (PTEN)
   05208 Chemical carcinogenesis - reactive oxygen species
    112656209 (PTEN)
   05230 Central carbon metabolism in cancer
    112656209 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112656209 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    112656209 (PTEN)
   05214 Glioma
    112656209 (PTEN)
   05218 Melanoma
    112656209 (PTEN)
   05215 Prostate cancer
    112656209 (PTEN)
   05213 Endometrial cancer
    112656209 (PTEN)
   05224 Breast cancer
    112656209 (PTEN)
   05222 Small cell lung cancer
    112656209 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112656209 (PTEN)
   05165 Human papillomavirus infection
    112656209 (PTEN)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    112656209 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    112656209 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112656209 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:clud01009]
    112656209 (PTEN)
Enzymes [BR:clud01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     112656209 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     112656209 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     112656209 (PTEN)
Protein phosphatases and associated proteins [BR:clud01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    112656209 (PTEN)
SSDB
Motif
Pfam: PTEN_C2 Tc-R-P PTP-SAK DSPc PTP-NADK Y_phosphatase PTPlike_phytase Y_phosphatase3 DUF3256
Other DBs
NCBI-GeneID: 112656209
NCBI-ProteinID: XP_025297213
Ensembl: ENSCAFG00020026101
LinkDB
Position
26:37060565..37166926
AA seq 403 aa
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 1212 nt   +upstreamnt  +downstreamnt
atgacagccatcatcaaggagatcgtcagcagaaacaaaaggcgctaccaggaggatggg
ttcgacttggacttgacctatatttatcccaacattattgctatggggtttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctgtgtgctgaaagacattatgataccgccaaa
tttaactgcagagttgcacagtatccttttgaagaccataatccaccacagctagaactt
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttctaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcatctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatctattcctccaattcaggacccacacgacgggaagacaagttcatgtac
tttgagttccctcagccattgcctgtgtgcggtgacatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaacacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagtatttgcagtatagaacgtgcagataatgacaaggaatatctagtactcacttta
acaaaaaatgatctcgacaaagcaaataaagacaaggccaaccgatatttttctccaaat
tttaaggtgaagctgtacttcacaaaaactgtagaggagccatcaaacccggaggctagc
agttcaacttctgtgacgccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgacccagagaatgaaccctttgatgaagatcagcacacacaaatc
acaaaagtctga

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