KEGG   Canis lupus dingo (dingo): 112660315
Entry
112660315         CDS       T08371                                 
Symbol
PINK1
Name
(RefSeq) LOW QUALITY PROTEIN: serine/threonine-protein kinase PINK1, mitochondrial
  KO
K05688  PTEN induced putative kinase 1 [EC:2.7.11.1]
Organism
clud  Canis lupus dingo (dingo)
Pathway
clud04137  Mitophagy - animal
clud05012  Parkinson disease
clud05014  Amyotrophic lateral sclerosis
clud05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:clud00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    112660315 (PINK1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    112660315 (PINK1)
   05014 Amyotrophic lateral sclerosis
    112660315 (PINK1)
   05022 Pathways of neurodegeneration - multiple diseases
    112660315 (PINK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:clud01001]
    112660315 (PINK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:clud04131]
    112660315 (PINK1)
   03029 Mitochondrial biogenesis [BR:clud03029]
    112660315 (PINK1)
Enzymes [BR:clud01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     112660315 (PINK1)
Protein kinases [BR:clud01001]
 Serine/threonine kinases: Other
  NKF2 family
   112660315 (PINK1)
Membrane trafficking [BR:clud04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    112660315 (PINK1)
Mitochondrial biogenesis [BR:clud03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    112660315 (PINK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like APH
Other DBs
NCBI-GeneID: 112660315
NCBI-ProteinID: XP_025303651
Ensembl: ENSCAFG00020008517
UniProt: A0A8C0K645
LinkDB
Position
2
AA seq 582 aa
MAVRQALGRGLQLGRALLLRFTAKPGPACGWGRPERPGPAAGWGRGERPGQAAGPGAERR
RLGLGLPDRYRFFRQSVAGLAARLQRQFAVRARGGAGPCGRAVFLAFGLGLGLIEEKQAE
GRRAAAACREIQAIFTQKNKLLPDPLDTRRWQGFRLEEYLIGQSIGKGCSAAVYEATMPV
LPQNREVVKSIRPLPGRGPDVDAREEEPASQAPTFPLAIKMMWNISAGSSSEAIFSTMSQ
ELVPASRVALAGEYGAVTYRKSKGGPKQLAPHPNIIRVFRAFTSSVPLLPGALVDYPDVL
PPRLHPEGLGHGRTLFLVMKNYPCTLRQYLRENTPSPRLATVMILQLLEAVDHLVQQGVA
HRDLKSDNILVELDADGCPWLVIADFGCCLADERTGLQLPFTSWYVDRGGNGCLMAPEVS
TACPGPRAVIDYSKADAWAVGTLAYEIFGLPNPFYGQGRAHLESRSYQEAQLPAMPESVP
LDARQLVRSLLQREASKRPSARVAANVLHLSLWGEHTLALKNLKLDKMIGWLLQQSAATL
LADRLTEKSCVETKMKMLFLANLEYEALCQAALLLYSWRAAP
NT seq 1749 nt   +upstreamnt  +downstreamnt
atggcggtgcgacaggcgctgggccgcggcctgcagctgggccgagcgctgctgctgcgc
ttcacggccaagcctggcccggcctgcggctgggggcggcccgagcggccgggccccgcg
gcgggctggggccgcggagaacgcccgggccaggccgcgggacccggcgcggagcggcgc
aggctggggctcgggctccccgaccgctaccgcttcttccgccagtcggtggccgggctg
gcggcgcgactccagcggcagttcgcggtgcgggcccggggtggcgcgggcccttgcggc
cgggccgtctttctggccttcgggttgggcctgggcctcatcgaggagaagcaggcggag
ggccggcgggcggcggcggcttgtcgggagatccaggcaattttcacccagaaaaacaag
ctgcttcctgaccctttggacactagacgctggcagggcttccggctggaggagtatctg
atagggcagtccattggcaagggttgcagtgctgctgtgtatgaagccaccatgcctgtg
ttgccccagaaccgggaggtggtgaagagcatcagacctcttccaggccgaggcccagat
gtcgatgcacgagaagaggagccagcttcacaggcccctacctttcccttagccatcaag
atgatgtggaatatctcggcgggctcctccagtgaagccatctttagcacaatgagccag
gaactcgtcccagctagtcgagtggccttggctggggagtacggagcggtcacttacaga
aaatccaagggtggtcccaagcagctggcccctcaccccaacatcatccgggtctttcgt
gccttcacctcttctgtaccactgctgccaggagccctggttgactaccctgatgtgctg
cccccacgtcttcaccccgaaggcctgggccacgggcggacgctcttcctcgttatgaag
aactacccctgtacgctgcgccagtacctccgcgagaacaccccaagtccccgcctcgcc
accgtgatgatcttacagctgctggaggcagtggatcatctggttcaacagggcgtcgcg
cacagagacttaaaatctgacaacattctcgtggagttggatgcagatggctgcccctgg
ctggtgatcgcagactttggctgctgcctggctgacgagcgcaccggcctgcagctgcct
ttcaccagctggtatgtggatcggggcggaaacggctgcctgatggctccagaggtgtct
actgcctgcccaggccccagggcagtgatcgactacagtaaggctgatgcctgggccgtg
ggtacgcttgcctatgaaatcttcgggctccccaatcccttttatggccagggcagggcc
caccttgaaagccgcagttaccaggaggctcagctgcccgcgatgcccgagtcagtccct
ctggatgcaagacagctggtgaggtcactgctccagcgagaggccagcaagagaccatct
gcccgagtagctgctaatgtgcttcatttaagcctctggggtgaacatactctcgccctg
aagaatctaaaactagacaagatgattggctggctcctccagcagtcagctgccactctg
ctggctgaccggctcacggagaagagctgcgtggaaaccaagatgaagatgttatttcta
gccaacctggagtacgaagcgctgtgccaggcagccctgctcctctactcctggagagca
gccccgtga

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