Canis lupus dingo (dingo): 112662017
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Entry
112662017 CDS
T08371
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud01522
Endocrine resistance
clud04012
ErbB signaling pathway
clud04062
Chemokine signaling pathway
clud04148
Efferocytosis
clud04151
PI3K-Akt signaling pathway
clud04360
Axon guidance
clud04370
VEGF signaling pathway
clud04510
Focal adhesion
clud04670
Leukocyte transendothelial migration
clud04810
Regulation of actin cytoskeleton
clud04935
Growth hormone synthesis, secretion and action
clud05100
Bacterial invasion of epithelial cells
clud05135
Yersinia infection
clud05146
Amoebiasis
clud05163
Human cytomegalovirus infection
clud05165
Human papillomavirus infection
clud05170
Human immunodeficiency virus 1 infection
clud05200
Pathways in cancer
clud05202
Transcriptional misregulation in cancer
clud05205
Proteoglycans in cancer
clud05208
Chemical carcinogenesis - reactive oxygen species
clud05222
Small cell lung cancer
clud05417
Lipid and atherosclerosis
clud05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
112662017 (PTK2)
04370 VEGF signaling pathway
112662017 (PTK2)
04151 PI3K-Akt signaling pathway
112662017 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
112662017 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
112662017 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
112662017 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
112662017 (PTK2)
04062 Chemokine signaling pathway
112662017 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
112662017 (PTK2)
09158 Development and regeneration
04360 Axon guidance
112662017 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112662017 (PTK2)
05202 Transcriptional misregulation in cancer
112662017 (PTK2)
05205 Proteoglycans in cancer
112662017 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
112662017 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
112662017 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
112662017 (PTK2)
05163 Human cytomegalovirus infection
112662017 (PTK2)
05165 Human papillomavirus infection
112662017 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
112662017 (PTK2)
05100 Bacterial invasion of epithelial cells
112662017 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
112662017 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112662017 (PTK2)
05418 Fluid shear stress and atherosclerosis
112662017 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
112662017 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
clud01001
]
112662017 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
clud01009
]
112662017 (PTK2)
Enzymes [BR:
clud01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
112662017 (PTK2)
Protein kinases [BR:
clud01001
]
Non-receptor tyrosine kinases
FAK family
112662017 (PTK2)
Protein phosphatases and associated proteins [BR:
clud01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
112662017 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
112662017
NCBI-ProteinID:
XP_048949075
Ensembl:
ENSCAFG00020015459
LinkDB
All DBs
Position
13:complement(35586299..35852772)
Genome browser
AA seq
1086 aa
AA seq
DB search
MAAAYLDPNLNHTPNSSTKTHLGAGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGD
ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEW
KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSY
WEMRGNALEKKSNYEVLEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESI
LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQ
TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFII
RPQKEGERALPSIPKLANSEKQGVRTHAVSVSGVSPCQHKVKKARRFLPLVFCSHEPSPT
DEISGDETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYMSPEN
PALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGE
LRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFG
LSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGV
KNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQ
QEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSG
YPASHGIPAMAGSIYPGQASLLDQTDSWNHRPQEISMWQPNMEDSAALDLRGIGQVLPTH
LMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPTGNQHIYQPVGK
PDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKLQPQEISPPPTANLDRSNDRVYE
NVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLPVLPASTHREIEMA
QKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLRML
GPTRPH
NT seq
3261 nt
NT seq
+upstream
nt +downstream
nt
atggcagctgcttacctcgacccaaacttgaatcacacaccgaattcaagtaccaagact
cacctgggtgccggggtggaacgctccccgggggcaatggagagagtgttgaaggtcttt
cattattttgaaaacagcagtgagccagctacttgggccagtattatcaggcacggagat
gctactgatgtcaggggcatcattcagaagatagtggacagtcacaaagtaaagcacgtg
gcctgctatggatttcgcctcagtcacctgcggtcagaggaggttcactggctccatttg
gatatgggtgtctccaatgtgagggagaagtatgaacttgcacacccaccagaggagtgg
aaatacgaattgagaattcgttatttgccaaaaggatttctaaaccagtttactgaagac
aagccaactctgaatttcttctatcaacaggtgaagagtgactacatgtctgagatagct
gaccgcgtggaccaggacattgctttgaagctgggctgtctagaaatacggcgctcatac
tgggagatgagaggcaatgcgctggagaagaagtctaactatgaagtgctggaaaaagat
gttggtttgaagcgattttttcctaggagtttactggattctgtcaaggcaaaaacacta
agaaagctgatccaacagacatttagacagtttgccaaccttaacagagaagaaagtatt
ctgaagttctttgagatcctctccccagtatacagatttgataaagaatgtttcaagtgt
gctctggggtcaagctggattatttcagtggaactggcaatcggcccagaagaaggaatc
agttacctcacggacaaaggctgcaaccccacacacctggctgacttcaatcaggtgcag
accattcagtattcaaacagcgaagacaaggacaggaaaggaatgctacagttgaagatc
gccggcgcccccgagcctctgacagtgacagcgccatccctaaccatcgccgagaatatg
gctgacttgatagatgggtactgccggctggtgaacggggccacgcagtcttttatcatc
agaccccagaaagaaggtgaacgggctttgccatcgataccaaagctggccaacagcgag
aagcaaggcgtgcggacacacgcggtctccgtgtcaggagtcagtccctgccaacataaa
gttaagaaagctaggcgctttctccctttggtcttctgttcccatgagccttctcctacg
gatgaaattagtggggacgaaacagatgattatgctgagattatagatgaagaagatacc
tacaccatgccgtcaaccagggattatgagattcagagagaaagaatcgagcttggacgc
tgcatcggggaaggccagtttggagatgtccatcaaggcgtctatatgagcccagagaat
ccagctttggcggttgcaattaaaacatgtaaaaactgtacttcggacagcgtgagagag
aaattccttcaagaagccttaacaatgcgtcagtttgaccaccctcacattgtgaagttg
attggcgtcatcacggagaaccccgtctggataatcatggagctgtgcacgcttggagag
ctgaggtcatttctgcaagtaaggaagtacagtttggatctagcatctttgatcctgtat
gcctatcagcttagtacagctctcgcgtatctggagagcaaaagatttgtgcacagggac
attgctgctcggaatgttctggtgtcctcaaacgattgtgtaaaactaggagactttgga
ttatcccgatatatggaagacagtacttactacaaagcttccaaaggaaaattgcctatt
aagtggatggctccagagtccatcaattttcgacgttttacctcagctagtgatgtatgg
atgtttggtgtatgtatgtgggagatactgatgcatggtgtgaagccttttcaaggagtg
aagaacaatgatgtgatcggtcgaattgagaatggggagagattaccaatgcctccaaat
tgccctcctaccctctacagccttatgacgaaatgctgggcttatgaccccagcaggcgg
ccccggttcactgagctcaaagctcagctcagcacaatcctggaggaggagaaggtgcag
caagaagaacggatgaggatggagtccagaagacaggtcacagtatcctgggactccgga
gggtccgacgaagctccacccaagcccagcagacccggttaccctagtccaaggtccagc
gaaggattttatcccagtccacagcacatggtacaaaccaatcattaccaggtctctggc
tatcctgcttcacatgggatcccagccatggccggcagcatctacccaggtcaggcatct
cttttggaccagacggattcatggaatcatagaccacaggagatatcaatgtggcagccc
aacatggaggactctgctgcgctggacctgcgagggattgggcaggtattgccgacccac
ctaatggaagagcggctaatccggcagcagcaggaaatggaagaagatcagcgctggctg
gaaaaagaggagagatttctgaaacctgatgtgcggctctctcgaggcagcattgacagg
gaggatggaagtctccagggcccgactggaaaccaacacatataccagcctgtgggtaaa
ccagatcctgcagctccgccaaagaaaccgccacggcctggagcccctggtcacctgggc
agcctcgccagcctcagcagccccggggacagttacaatgagggcgtcaagcttcagccc
caggaaatcagccccccgcccactgccaacctggaccggtccaacgacagggtgtacgag
aatgtgacgggcctggtgaaggctgtcatcgaaatgtccagcaagatccagccagcccca
ccggaggagtatgttcccatggtgaaggaagtcggcctggccctgcggacgttactggcc
actgtggacgagacccttccggtcctgccggccagcacgcaccgagagattgagatggcc
cagaagctgttgaactccgacctgggtgagctcatcaacaagatgaagctggcccagcag
tacgtcatgaccagtctccagcaggagtacaaaaagcagatgctgaccgctgctcatgcc
ttggccgtggatgccaaaaacttactcgatgtcattgaccaagcgagactgcggatgctc
ggaccaacgaggccacactga
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