Canis lupus dingo (dingo): 112662652 Help Entry 112662652         CDS       T08371                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism clud  Canis lupus dingo (dingo) Pathway clud00230   Purine metabolism clud01100   Metabolic pathways clud01522   Endocrine resistance clud04015   Rap1 signaling pathway clud04020   Calcium signaling pathway clud04022   cGMP-PKG signaling pathway clud04024   cAMP signaling pathway clud04062   Chemokine signaling pathway clud04072   Phospholipase D signaling pathway clud04081   Hormone signaling clud04082   Neuroactive ligand signaling clud04114   Oocyte meiosis clud04211   Longevity regulating pathway clud04213   Longevity regulating pathway - multiple species clud04261   Adrenergic signaling in cardiomyocytes clud04270   Vascular smooth muscle contraction clud04371   Apelin signaling pathway clud04540   Gap junction clud04611   Platelet activation clud04713   Circadian entrainment clud04714   Thermogenesis clud04723   Retrograde endocannabinoid signaling clud04724   Glutamatergic synapse clud04725   Cholinergic synapse clud04727   GABAergic synapse clud04750   Inflammatory mediator regulation of TRP channels clud04911   Insulin secretion clud04912   GnRH signaling pathway clud04913   Ovarian steroidogenesis clud04914   Progesterone-mediated oocyte maturation clud04915   Estrogen signaling pathway clud04916   Melanogenesis clud04918   Thyroid hormone synthesis clud04921   Oxytocin signaling pathway clud04922   Glucagon signaling pathway clud04923   Regulation of lipolysis in adipocytes clud04925   Aldosterone synthesis and secretion clud04926   Relaxin signaling pathway clud04927   Cortisol synthesis and secretion clud04928   Parathyroid hormone synthesis, secretion and action clud04934   Cushing syndrome clud04935   Growth hormone synthesis, secretion and action clud04970   Salivary secretion clud04971   Gastric acid secretion clud04972   Pancreatic secretion clud04976   Bile secretion clud05032   Morphine addiction clud05163   Human cytomegalovirus infection clud05166   Human T-cell leukemia virus 1 infection clud05200   Pathways in cancer clud05207   Chemical carcinogenesis - receptor activation clud05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:clud00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     112662652 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     112662652 (ADCY2)    04371 Apelin signaling pathway     112662652 (ADCY2)    04020 Calcium signaling pathway     112662652 (ADCY2)    04072 Phospholipase D signaling pathway     112662652 (ADCY2)    04024 cAMP signaling pathway     112662652 (ADCY2)    04022 cGMP-PKG signaling pathway     112662652 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     112662652 (ADCY2)    04081 Hormone signaling     112662652 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     112662652 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     112662652 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112662652 (ADCY2)    04062 Chemokine signaling pathway     112662652 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     112662652 (ADCY2)    04922 Glucagon signaling pathway     112662652 (ADCY2)    04923 Regulation of lipolysis in adipocytes     112662652 (ADCY2)    04912 GnRH signaling pathway     112662652 (ADCY2)    04913 Ovarian steroidogenesis     112662652 (ADCY2)    04915 Estrogen signaling pathway     112662652 (ADCY2)    04914 Progesterone-mediated oocyte maturation     112662652 (ADCY2)    04921 Oxytocin signaling pathway     112662652 (ADCY2)    04926 Relaxin signaling pathway     112662652 (ADCY2)    04935 Growth hormone synthesis, secretion and action     112662652 (ADCY2)    04918 Thyroid hormone synthesis     112662652 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     112662652 (ADCY2)    04916 Melanogenesis     112662652 (ADCY2)    04925 Aldosterone synthesis and secretion     112662652 (ADCY2)    04927 Cortisol synthesis and secretion     112662652 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     112662652 (ADCY2)    04270 Vascular smooth muscle contraction     112662652 (ADCY2)   09154 Digestive system    04970 Salivary secretion     112662652 (ADCY2)    04971 Gastric acid secretion     112662652 (ADCY2)    04972 Pancreatic secretion     112662652 (ADCY2)    04976 Bile secretion     112662652 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     112662652 (ADCY2)    04727 GABAergic synapse     112662652 (ADCY2)    04725 Cholinergic synapse     112662652 (ADCY2)    04723 Retrograde endocannabinoid signaling     112662652 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     112662652 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     112662652 (ADCY2)    04213 Longevity regulating pathway - multiple species     112662652 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     112662652 (ADCY2)    04714 Thermogenesis     112662652 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112662652 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     112662652 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112662652 (ADCY2)    05163 Human cytomegalovirus infection     112662652 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     112662652 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     112662652 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     112662652 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     112662652 (ADCY2) Enzymes [BR:clud01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      112662652 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  112662652 NCBI-ProteinID:  XP_025307021 Ensembl:  ENSCAFG00020022544 LinkDB All DBs Position 34:complement(6117353..6505320) Genome browser AA seq 1098 aa AA seqDB search MWREAMRRRRYLRDRAEAAAAAAGGGGGGGGGGLQRSRDWLYESYYCMSQQHPLIVFLLL IVMGACLALLAVFFALRLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLV IWICLVAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSASHTIV LSVCLSATPGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIK LEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSIL YADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLP NHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTL ANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRS PHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQH NFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEKEYR ATALPAFKYYVTCACLIFFCIFIVQILVLPKTSILGISFGAAFLLLAFILFICFAGQLLQ CSKKASASLLWLLKSSGIIADRPWPRVSLTVLTTAIILTMAVFNMFFLSDPEETIPPTAN TSNMSLSALSNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVAY NTILLHTHAHVLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFL WKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYDCVCVMFASI PDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSA VPSQEHAQEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGVIGA QKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSVILQTLGYACTCRGIINVKGKGELKT YFVNTEMSRSLSQSNLAS NT seq 3297 nt NT seq  +upstreamnt  +downstreamnt atgtggcgggaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggcggcggcg gcggcggcgggcggcggcggcggcggcggcggcggcgggctgcagcggtcccgggactgg ctgtacgagtcctactactgcatgagccagcagcacccgctcatcgtcttcctgctgctc atcgtcatgggcgcctgcctcgccctgctcgccgtcttcttcgcgctccggctggaagtt gaagaccacgtggcgtttttaataacggtcccgacggccctggcgattttctttgcaata ttcatccttgtctgcatcgagtctgtgttcaaaaagctgctccgccttttctccttggtg atatggatatgtctcgtggccatggggtacctgttcatgtgctttggaggcaccgtctct ccctgggaccaggtgtcgttcttcctcttcatcatcttcgtggtgtacaccatgctgccc ttcaacatgcgagatgccatcatcgccagcgtgctcacctccgcctcccacaccatcgtg ctgagcgtctgcctgtccgcgacgccgggggccaaggagcacctggtctggcagatcctg gccaatgtgatcattttcatctgtgggaacctggcaggggcataccacaagcacctcatg gaacttgccctgcagcagacatatcaggacacatgcaattgcatcaagtcccggatcaag ctggaatttgaaaagcgtcagcaggaacggcttttgctctctctgctgcctgctcacata gccatggaaatgaaagctgagatcatccagaggcttcagggccccaaagccggccaaatg gaaaacacaaacaactttcacaacctgtatgtcaagcgacacaccaacgtgagtatcctg tatgctgacattgttggcttcacccggctggccagtgactgctccccaggagagctggtc cacatgctgaacgagctgtttggaaagtttgatcaaattgcaaaggagaatgaatgcatg agaataaaaattttgggagactgctactattgtgtatccggactccctatatctctccca aaccatgccaagaactgtgtgaaaatggggctggacatgtgtgaagccataaagaaggtg agggatgcaactggcgtggatattaacatgcgcgtgggagtgcattccgggaacgtcctt tgcggggtcatcggcctgcagaagtggcagtacgacgtgtggtcacatgacgtgaccctg gccaatcacatggaggctggaggggtccctggacgtgttcacatttcttctgtcaccctg gaacacttgaacggcgcttataaagtggaggaaggagacggtgacatcagagacccatat ttaaagcagcacctggtgaagacctactttgtaatcaaccccaagggagaacgaaggagt cctcacctcttcagacctcgccacaccctcgatggagccaagatgagggcttctgttcgc atgacccggtacctggagtcctggggagcggccaagccctttgcacacctgcatcatcga gacagcatgaccacagagaatggcaagatcagcacgacggatgtgccaatgggtcagcat aatttccaaaatcgtaccttgagaaccaagtcccaaaagaaaagatttgaagaagaatta aatgaaaggatgattcaagcaattgatggaattaatgcacaaaagcagtggctcaagtct gaagacattcagagaatctcactcctgttctacaataaaatactagaaaaagaataccga gccactgcactgccagcgtttaagtactacgtcacctgcgcctgtctcatattcttctgc atctttattgtacagattctggtattaccaaaaacatcgattctggggatctcctttgga gctgcatttctcctgctcgcctttatccttttcatctgctttgctggacagcttttgcaa tgcagcaagaaggcatccgcctctctcctgtggctgttgaagtcgtcgggcatcatcgcc gaccggccctggccgcgggtctccctcaccgtcctcaccacggccatcattctgaccatg gccgtgttcaacatgtttttcctgagtgatccagaggaaacaattcctccaactgccaat acatcaaacatgagtctgtctgccttaagtaatcaggcagcgattctgcgtgcacaaaat ctgtttttcctcccgtactttatctacagctgcattctgggtttgatttcctgctcggtg ttcctgcgggtgaattacgagttgaaaatgttgatcatgatggtggcattggtggcctac aacaccatcctcctgcacactcatgcccacgtcctggacgactacagccaggtcttattt gagagaccaggcatttggaaagacctgaagaccatgggctcagtgtctctctttatattc ttcatcacactgcttgttctgggtagacagaatgaatattactgtaggttagacttctta tggaagaacaaattcaaaaaagaacgggaggagatagagaccatggagaacctgaaccgt gtgctgctggagaacgtgctgcccgcacatgtggccgagcatttcctggcccggagcctg aagaacgaggacttataccaccaatcctatgactgtgtctgcgtcatgtttgcctccatt ccggatttcaaagaattctacacagaatcagatgtgaacaaggagggtttggaatgcctt cggctcctgaatgagatcatcgccgactttgatgatctgctgtccaagccaaaattcagt ggagttgaaaagatcaagaccattggcagcacatacatggcagcgaccggtctgagcgcc gtgccgagccaggagcatgcccaggagcccgagaggcagtacatgcacattggcaccatg gtggagtttgcctttgccctggtggcgaaactggatgctatcaacaagcactccttcaat gacttcaagttgcgagtgggtattaaccatgggcctgtaatagctggtgtgattggagcc cagaagccacagtatgatatctggggtaacacggtgaacgtggccagtaggatggacagc accggcgtgctggacaaaatacaggtcaccgaggagaccagcgtcatccttcagaccctg gggtacgcatgcacgtgtcgagggataatcaacgtgaaaggcaagggggagctgaagacg tactttgtaaacacggaaatgtcaaggtccctttcccagagcaacttggcatcctga

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