Canis lupus dingo (dingo): 112666443 Help Entry 112666443         CDS       T08371                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism clud  Canis lupus dingo (dingo) Pathway clud04010   MAPK signaling pathway clud04014   Ras signaling pathway clud04015   Rap1 signaling pathway clud04022   cGMP-PKG signaling pathway clud04066   HIF-1 signaling pathway clud04068   FoxO signaling pathway clud04072   Phospholipase D signaling pathway clud04081   Hormone signaling clud04150   mTOR signaling pathway clud04151   PI3K-Akt signaling pathway clud04152   AMPK signaling pathway clud04211   Longevity regulating pathway clud04213   Longevity regulating pathway - multiple species clud04520   Adherens junction clud04910   Insulin signaling pathway clud04913   Ovarian steroidogenesis clud04923   Regulation of lipolysis in adipocytes clud04930   Type II diabetes mellitus clud04931   Insulin resistance clud04932   Non-alcoholic fatty liver disease clud04960   Aldosterone-regulated sodium reabsorption clud05010   Alzheimer disease clud05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:clud00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112666443 (INSR)    04014 Ras signaling pathway     112666443 (INSR)    04015 Rap1 signaling pathway     112666443 (INSR)    04066 HIF-1 signaling pathway     112666443 (INSR)    04068 FoxO signaling pathway     112666443 (INSR)    04072 Phospholipase D signaling pathway     112666443 (INSR)    04022 cGMP-PKG signaling pathway     112666443 (INSR)    04151 PI3K-Akt signaling pathway     112666443 (INSR)    04152 AMPK signaling pathway     112666443 (INSR)    04150 mTOR signaling pathway     112666443 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     112666443 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     112666443 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     112666443 (INSR)    04923 Regulation of lipolysis in adipocytes     112666443 (INSR)    04913 Ovarian steroidogenesis     112666443 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     112666443 (INSR)   09149 Aging    04211 Longevity regulating pathway     112666443 (INSR)    04213 Longevity regulating pathway - multiple species     112666443 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     112666443 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     112666443 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     112666443 (INSR)    04932 Non-alcoholic fatty liver disease     112666443 (INSR)    04931 Insulin resistance     112666443 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:clud01001]     112666443 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:clud04090]     112666443 (INSR) Enzymes [BR:clud01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      112666443 (INSR) Protein kinases [BR:clud01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    112666443 (INSR) CD molecules [BR:clud04090]  Proteins   112666443 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  112666443 NCBI-ProteinID:  XP_025313168 Ensembl:  ENSCAFG00020023010 LinkDB All DBs Position 20:complement(52314423..52449522) Genome browser AA seq 1344 aa AA seqDB search MDIRNNLTRLHELANCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLE SLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLAT IDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQK VCPTICKSHGCTAEGLCCHSECLGNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQD WRCVNFSFCQDLHNKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPK VCHILEGEKTIDSVTSAQELRGCTVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKI RRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHY NPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWE PYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPG WLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQ IILKWKPPSDPNGNITHYLVFWERQAEDSELYELDYCLKGLKLPSRTWSPPFEAEGSQKH NQSEYEESAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKSSSSPGAEDTRP SRKRRALSDAGNVTAAIPTVPGFPNTSTSTPTSPEEHKPFEKVVNKESLVISGLRHFTGY RIELQACNQDSPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPN GLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTE ATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPE YLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDIVKGEPETRVAVKT VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSL RPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDF GMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQ GLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSF PEVSFFHSEENKAPESEELEMEFEDMESVPLDRASHSQREEAGGRDAGSSLGLKRSYEEH IPYTHMNGGKKNGRILTLPRSNPS NT seq 4035 nt NT seq  +upstreamnt  +downstreamnt atggatatccggaacaacctaacgaggctgcatgagctggccaactgctcggtcattgaa ggacatttgcagatactgttaatgttcaaaacgaggcccgaggatttccgagacctcagt ttccccaaactcatcatgatcactgattacttgctgctcttccgggtctatgggctggag agcctgaaggacctgttccccaacctcacggtcatccgaggctcgcgcctcttcttcaac tacgcgctggtcatcttcgagatggtccacctgaaggagcttggcctctacagcttgatg aacatcacccggggctccgtccgcatcgagaagaacaatgagctctgctacctggccacc atcgactggtcccgcatcctggattctgtggaggataattatattgtgctgaacaaagac gacaacgaggagtgtggggacatctgtccaggcactgccaagggcaagaccaactgccct gccactgtcatcaatgggcagtttgtcgagcggtgttggacacacagccactgccagaaa gtttgtccgaccatctgcaagtcacatggctgcaccgccgagggcctctgctgccacagc gagtgtttaggcaactgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaat ttctacctggatggcaggtgcgtggagacctgcccacccccatactaccacttccaagac tggcgctgcgtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactcccgg agacagggctgccaccagtacgtcatccacaataacaagtgcatccccgagtgcccctct ggctacacgatgaattccagcaacctgatgtgcactccgtgcctgggcccctgtcccaag gtctgccacattctggaaggcgagaagaccatcgactcagtgacgtctgcccaggagctt cgaggctgcactgttgtcaacggaagtctaatcatcaacattcgagggggcaacaacctg gcggccgagctggaggccaacctcggactcattgaagagatttccgggtacctgaaaatc cggagatcctatgctcttgtgtctctttcctttttccggaagttgcggctgattcgaggg gagaccttggagatcgggaactactctttctatgccttggacaaccagaacctaaggcag ctatgggactggagcaaacacaacctcaccatcactcaggggaaactcttcttccactat aatcccaaactctgcttgtctgagatccacaagatggaggaagtctcaggaaccaagggg cgccaggagaggaacgacattgccctgaagaccaacggggaccaggcgtcttgtgaaaac gaactacttaaattttcttacattcggacgtcttatgacaagatcttgctgaaatgggag ccctactggccccctgacttccgagacctcctggggttcatgctcttctacaaagaggcc ccttatcagaatgtgaccgagtttgatgggcaggacgcgtgtggctccaacagctggacg gtggtggacattgacccacctctgcggtccaacgaccccaaatcgcagaaccacccgggg tggctgatgcggggtctcaagccctggacccaatatgccatctttgtcaagaccttggtc accttttctgatgaacgccgcacgtatggagccaagagtgacatcatctatgtgcagaca gatgccactaatccttccgtccccctggatccaatctcggtttcgaattcctcgtcccag attattctgaagtggaagcctccctctgaccccaatggcaatatcacgcactacctggtt ttctgggagaggcaggccgaagacagtgagctctatgagttggattattgcctcaaaggg ttgaagctgccctcccggacctggtctccgccgttcgaggccgagggctcccagaagcac aaccagagtgaatacgaggagtctgccggcgaatgctgctcctgccccaaaacggactct cagatcctcaaggagctagaggagtcctcttttaggaagacgtttgaggattacctgcac aacgtggtgtttgtccccagaaaatcctcttcgagccctggtgctgaggacactaggcca tcgaggaaacgcagggcgctcagtgatgctggcaacgtgacagcagctatacccacagtt cccggtttccccaacacctcgaccagcacgcccacgagcccggaggagcacaagcccttc gagaaagtggtgaacaaagaatctctggtcatctccggtctgcgccacttcactggctac cgcatcgagctgcaggcttgcaaccaagactcccccgaggagaggtgcagcgtggcggcc tatgtcagcgccaggaccatgcccgaagccaaggcagacgacatcgttggccccgtgacc cacgaaatcttcgagaacaatgtcgttcacttgatgtggcaggagccaaaggaacccaat ggtctgatcgtgctttatgaagtgagttaccgacggtatggcgatgaggagctgcacctg tgtgtctcccggaggcattttgctctggagcgtggctgcaggctacgcgggctgcctccg gggaattacagcgtgcgagtccgggccacctccctggcgggtaatggctcctggacagaa gccacctatttctacgtgacagactatttagatgtcccatcgaatattgcaaaaattatc atcggccccctcatctttgtctttctcttcagtgttgtgattggaagtatttacctgttc ctgagaaagaggcagccggatgggccactgggaccgctgtatgcttcttcaaaccctgag tacctcagtgccagtgatgtgtttccatgttctgtgtatgtgccggacgagtgggaggtg ccgcgggagaagatcaccctcctgcgcgagctggggcaaggctccttcggcatggtgtac gagggcaacgccagggacatcgtcaagggtgagcccgagacccgcgtggccgtcaagacc gtcaacgagtccgccagcctgcgagagaggatcgagtttctcaatgaggcatcagtcatg aagggcttcacctgtcaccacgtggtccgcctcctgggggtggtgtccaaaggccaaccg acgctggtggtgatggagctgatggctcatggagacctgaagagctacctccgctccctg cggccggaggctgagaataaccccggccgccctccgcctaccctgcaagagatgattcag atggcggcggagatcgccgacgggatggcctacctgaacgccaagaagtttgtgcaccgg gatctagcagcccgaaactgcatggttgcccacgatttcactgtcaaaattggagacttt gggatgaccagagacatctatgagacggattactatcggaaaggaggcaagggtctgctc cccgtgcggtggatggcaccggagtccctgaaggacggggtctttaccacttcttctgac atgtggtcctttggcgtggtcctttgggaaatcaccagcttggcagagcagccttaccaa ggcctgtctaatgaacaggtgttgaaatttgtcatggacggagggtatctggatcaaccc gacaattgtccagagagagtcactgacctgatgcgcatgtgctggcagttcaatcccaag atgcggcccaccttcctggagattgtcgacctgctcaaggatgatctgcaccccagcttt ccagaagtttccttcttccacagcgaggagaacaaggcacccgagagcgaggagttggag atggagtttgaggacatggagagtgtccccctggatcgggcctcacactctcagagggag gaggccgggggccgggatgcagggtcctcgctgggcctaaagcggagctacgaggagcac atcccctacactcacatgaacgggggcaagaaaaatggacggattctgactctgccaagg tcgaatccttcctaa

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