KEGG   Cyclopterus lumpus (lumpfish): 117727228
Entry
117727228         CDS       T09199                                 
Symbol
cad
Name
(RefSeq) CAD protein
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
clum  Cyclopterus lumpus (lumpfish)
Pathway
clum00220  Arginine biosynthesis
clum00240  Pyrimidine metabolism
clum00250  Alanine, aspartate and glutamate metabolism
clum01100  Metabolic pathways
clum01240  Biosynthesis of cofactors
Module
clum_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:clum00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    117727228 (cad)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    117727228 (cad)
   00220 Arginine biosynthesis
    117727228 (cad)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:clum01002]
    117727228 (cad)
Enzymes [BR:clum01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     117727228 (cad)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     117727228 (cad)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     117727228 (cad)
Peptidases and inhibitors [BR:clum01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   117727228 (cad)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   117727228 (cad)
SSDB
Motif
Pfam: CPSase_L_D2 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 MGS Dala_Dala_lig_C ATP-grasp ATPgrasp_Ter Amidohydro_1 ATP-grasp_3 Peptidase_C26
Other DBs
NCBI-GeneID: 117727228
NCBI-ProteinID: XP_034383277
Ensembl: ENSCLMG00005012859
LinkDB
Position
24:16093149..16116995
AA seq 2235 aa
MSKMATLILEDGTTFKGLLFGADVSVSGEVVFQTGMVGYPEALTDPSYRCQLLTLTYPLV
GNYGVPQDEEGEFGLSQWFESSKIHAAALIIGELSDNPSHFSSVKSLDQWLKEQGIPGLQ
GIDTRRLTKKIREKGTMLGKLVVDGTPEDSIPFDNPDKRNLVQEVSMKEPRVFNPNGSVR
ITVVDCGIKYNQIRCLAQRGACVTVVPWDHPLDSTDFDGLFISNGPGDPEFCQTTINNVK
KVICAEHPKPLFGICLGHQLLSLVIGAKTFKMKYGNRGHNQPCIHKGTDRCFITSQNHGF
AVDPSTLPEDWDILFTNANDQTNEGIVHNTKPLFSVQFHPEHMAGPTDLVGLFDVFLDTV
KDHKEGKATTSVKQRLMDHLTYPDSPNPEEVLRPRKVLILGSGGLSIGQAGEFDYSGSQA
IKALKEENIQTVLINPNIATVQTSKGLADKVYFLPITAEYVTQVIKNERPDGVLLTFGGQ
TALNCGVELTKLGVLEKYNVRVLGTPVASIEMTEDRKIFVEKMEEINEHVAPSEAALSVE
QALAAAERLGYPVLVRAAFALGGLGSGFANNREELISLVASAFFHTSQVLVDKSLKGWKE
IEYEVVRDAYDNCITVCNMENIDPLGIHTGESIVVAPSQTLNDHEYNMLRNTAIKVIRHL
GIVGECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLGLGIPLPQLK
NSVTNSTTANFEPSLDYCVVKVPRWDLSKFLRVSTQIGSSMKSVGEVMAIGRSFEEAFQK
ALRMVDENCVGFDHTIKPVSEKELQIPTDKRIFVLASAFRAGYTVDQLYELTKIDRWFLH
KMKNIADYEQLLETYHQDESAMPPEVMRKAKQLGFSDKQIAQAVQSTELVIRKLRHDWSI
LPVVKQIDTVAAEWPAHTNYLYLTYHGTEDDLGFHEQHIMVIGSGVYRIGSSVEFDWCAV
GCITELRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYERENPEGVILSMG
GQLPNNIAMSLHRQQCRILGTSPEFIDCAENRFKFSRMLDTIGISQPQWKELSDTETAMK
FCETVGYPCLVRPSYVLSGAAMNVAYGDSDLEKYLTNAVAVSKEYPVVISKFIQEAKEID
VDAVASDGVVMAIAVSEHVENAGVHSGDATLVTPPQDLNQKTMERIKMIVHAIGQELQVT
GPFNLQLIAKDDQLKVIECNVRVSRSFPFISKTLGVDLVALATQTIVGQDVEPLGLMRGK
GIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPKKNIL
LSIGSYKNKSELLPTVQALESMGYDLYASLGTADFYTEHGVKVKAVDWPFEEDDSEGPNK
EKQRSIMDYLEENHFDLVINLSMRNSGGRRLSSFVTKGYRTRRMAIDYSVPLIIDIKCTK
LFVQALHQVGPSPPVKTHIDSMTSQTLVRLPGLIDVHVHLREPGATHKEDFSSGTAAALA
GGVTMVCAMPNTSPAITDASTLALVQKLAKAGCRCDYALYLGAASDNAAVLPSIASQAVA
LKMYLNDTYSTLKMDNVSLWMEHFEKWPKQMPIVAHAEKQTVAAILMVAQLYQRPVHICH
VASKEEILIIRAAKQRGIQVTCEVAPHHLFLCEENVTEIGDGRAQVRPMLGTRDDMEALW
ENLDIIDCFATDHAPHSVEEKSGDSPPPGYPGLETMLPLLLTAVSDGRLTLDDIIKRLYD
NPRRIFNLPVQDNTYVEVDLEQEWVIPQAMQFTKSKWTPFQGLKVKGKVRRVVLRGEVAY
IDGQVLVPPGYGEDVKAWPAALIHLPEPVKESPKTPEHSRPTPPREALVRTRAPSPRRLV
GESRYLLPPRIHRSSDPGLTLEMVMLPAAAAAGDGYSHPPPLSRLLSPQSGPGLLPAGQL
SHFQTSPLLHPLVGQHILSVRQFSKEQISHLFNVAHTLRMMVQKERSLDLLKGKVMASMF
YEVSTRTSSSFAAAMQRLGGSVVHFCESTSSTQKGESLADSVQTMSCYADILVLRHPMPG
AVESASRHCRKPVINAGDGVGEHPTQALLDVFTIREELGTVNGMTITMVGDLKHGRTVHS
LAKLLTQYRITLRYVAPKDLHMPAEIISYVASKGIRQEEFESIEEALPETDVLYMTRIQK
ERFASEEEYMNCFGQFILTPHIMTVAKKKMVVMHPLPRVNEISVEVDTDPRAAYFRQAEN
GMYIRMALLATLLGR
NT seq 6708 nt   +upstreamnt  +downstreamnt
atgtcaaagatggcaaccttgattctagaggacggaaccacgttcaaagggctccttttt
ggcgcagatgtatcagtttcgggagaagttgtgtttcagacgggtatggtgggctacccc
gaggctcttactgacccatcctaccgctgccagctgctgaccctcacttaccctctggtg
ggcaactatggtgtcccgcaggacgaagagggagagtttggactcagccagtggtttgag
tcgtcaaagatccacgctgcagctctgattatcggagagctgtcggacaatcccagtcac
tttagttcagtcaagtcactggaccagtggctcaaagagcaagggatccctggattacaa
ggcatcgacacccgccgtctgaccaaaaagatcagagagaaggggaccatgttggggaag
ctggttgtggacgggactcctgaggacagtattccctttgataacccagacaagaggaac
ctggttcaggaagtctccatgaaggagcccagagtattcaaccccaacggtagcgtgcga
atcacagtggtggactgcggcatcaaatacaaccagatccgctgcctggctcagagggga
gcctgtgtcaccgttgtaccctgggaccacccgctggacagcacagattttgatggtttg
ttcatcagtaacggccccggggaccccgaattctgtcagaccaccatcaacaacgtgaag
aaggtgatctgcgcggaacatcccaagccgctttttggcatttgcctcggtcaccagctg
ctctctttagtcattggagcgaagaccttcaagatgaagtatggtaaccgtggccataac
cagccatgcatccataagggaacggatcgatgcttcatcaccagtcaaaaccacggcttc
gccgtcgaccccagcaccctgccggaagactgggacatcctcttcaccaacgccaatgat
cagaccaatgagggcatcgtgcacaacacaaaacccctgttcagtgttcagttccaccca
gagcacatggccggtcccacagacctggtcggcctgttcgatgtcttcctcgacaccgtg
aaagaccacaaggagggcaaggccaccacatctgtgaagcaacgtctcatggaccacctc
acctacccggattccccgaatcctgaggaggtattaagacccaggaaggtcctcatcctg
ggctctggcggactatccatcggccaggccggggagttcgactactccggctcccaggct
attaaagctctcaaggaagagaatatccagactgtgctgatcaacccaaacatcgccact
gtccagacctccaagggcctggctgacaaagtctacttcctgcctatcacggccgagtat
gtcactcaggtgattaagaatgagcgtccagacggcgtgctgctgaccttcggcggtcag
acggctctgaactgcggcgtggagctcaccaagctgggcgtcctggagaagtacaacgtt
cgtgttttgggaacacccgtggcatctatcgagatgaccgaagaccggaagatctttgtg
gagaagatggaagagatcaatgaacatgttgcacccagtgaagccgcgctgtctgttgag
caggcactggcagctgcagaacgcctcggctaccctgtcctggtgcgagccgcttttgct
cttggtggtctgggctcgggctttgccaacaatagagaggagctcatctctctggtggca
tcagccttcttccacacttcccaggtgctcgtggacaaatccctgaaaggctggaaggag
atcgagtacgaggtggtccgggatgcctatgacaactgtataactgtgtgtaatatggag
aatattgacccgctcggcattcatactggagaatccatcgtggtggcgcccagtcagacg
cttaacgaccacgaatacaacatgctgaggaacacggccatcaaagtcatcaggcacctc
ggcatcgtaggagagtgcaacatccagtacgctcttaacccagagtctgaacagtactac
atcatcgaggtgaatgcccgtctgtcacgaagctcggccctggccagtaaggcgacgggt
taccctcttgcatatgtcgcagctaaacttggcctggggatcccactgccacagctcaag
aactctgttaccaactcgacaacagcaaactttgagcctagtttggattactgcgtggtg
aaggtgcctcgctgggatctcagcaagttcctcagagtttccacacagattggcagctcc
atgaagagtgttggtgaggtgatggctatcggccgcagctttgaggaggccttccagaaa
gctctgaggatggtggacgagaactgtgttggctttgaccacaccatcaagcctgtttct
gagaaggagttgcagattcctacagacaagcgcatctttgttttggcgtcggcattcaga
gccggctacacggtggaccagctgtatgagctcaccaagatcgaccgctggttcctacac
aagatgaagaacatcgctgactacgagcagctgctggagacgtaccaccaggatgagagc
gccatgcctccagaggtgatgcgaaaggccaagcagctgggcttctcagacaaacagatc
gcacaagctgtacagagcacggagcttgtcataagaaagctgcgtcacgattggtccatt
ctccctgtagtgaagcagatcgatacagtggcggccgaatggcccgcccacacaaactac
ctgtacctgacctaccacggcacagaggacgatctgggcttccacgaacagcacatcatg
gtgatcggctccggcgtgtaccgcatcggcagcagcgtggagtttgactggtgtgcggtc
gggtgcatcacagagctcaggaagatgggctataagaccatcatggtgaactacaaccca
gagacggtcagtacagactatgacatgtgtgaccgtctctactttgatgagatctccttt
gaggtggtgatggacatctatgagcgggagaacccagagggagtgatcctctccatggga
ggccagctgcccaacaacatcgccatgtcgctgcaccgtcagcagtgccgcatcttggga
acctcccccgagttcatcgactgtgcagagaacaggttcaagttctcccgaatgctggac
accatcggaatcagccagccgcagtggaaggagctctccgacactgagactgctatgaag
ttttgtgaaactgtgggttatccctgcctggtccgtccttcctacgttctcagcggagcg
gccatgaacgtcgcctacggtgacagcgacctcgagaaatacctgaccaacgctgtagct
gtgtccaaggagtaccctgttgtgatctccaaattcatacaggaggccaaggagatagac
gtagacgcggttgccagtgacggggtcgtgatggccatcgcggtgtctgaacacgtggag
aacgccggcgttcactccggtgacgccacactggtgactccaccgcaggatctcaatcag
aagacgatggagaggatcaagatgatcgtccatgccattggccaggagctgcaggtcact
ggacctttcaacttgcagctgatcgccaaggatgaccaactgaaggtgatcgagtgcaat
gtccgagtctcccgctccttccccttcatatcaaagacactgggcgtggatcttgtggcc
ctggcaacacagactattgtggggcaggacgtggagcctttgggcctcatgagagggaaa
gggattgtaggagtgaaggttccccagttttcattctctcgcctggccggagccgacgtg
gtgctcggggtggagatgaccagcaccggcgaggtggcctgttttggggagaaccggtac
gaggcttacctcaaagccatgctctccacgggcttcaagatccctaaaaagaacatcctg
ctctccatcggcagctataagaacaagagtgagctgctgcccaccgtgcaggctctggag
tctatgggttatgacctctacgccagtctgggtactgcagacttctacacagaacatgga
gtcaaggtgaaagcagtggactggccttttgaggaggacgacagcgaggggcccaacaaa
gagaagcagcgcagcatcatggactacttggaggagaaccacttcgatctggtcatcaat
ctctccatgaggaacagtggaggtcgcagactctcctcctttgtcaccaagggttaccgg
acgagacgcatggccatcgactactctgtcccgctcatcatcgacatcaagtgcaccaag
ctctttgtccaggctcttcatcaggtcggtccgtctccaccagtgaaaacgcacattgac
agcatgacatcccagacgctggtccgtctgcctggtctgatcgacgtgcacgttcacctg
cgggagcctggtgccacacacaaggaggacttctcctctgggacagcagctgctctggca
ggaggagtcaccatggtgtgtgcgatgcccaatacttcccccgccatcactgacgccagc
accctggcgctggtacagaagctggccaaagcaggctgcaggtgtgactacgccctgtat
ttgggcgccgcttcagacaacgccgccgtcctgccgtccatcgctagtcaggctgtcgcc
ctgaagatgtacctgaacgacacgtactccaccctcaagatggacaacgtatctctctgg
atggagcactttgaaaagtggcccaagcagatgcccatcgtggctcacgctgagaagcag
acggtggccgcaatcctcatggtggcgcagctctaccagcggccagtgcacatctgccac
gtggcctccaaggaagagatcctgatcatcagagcagcgaagcagaggggcatccaggtc
acatgcgaggtggcccctcatcacctcttcctttgcgaggaaaacgtgacggagatcgga
gacggacgagcgcaggtccggcccatgctgggaacacgcgacgacatggaggctctctgg
gaaaacctggacatcatcgactgctttgccacggaccacgcgccccactctgttgaggag
aagagcggggatagtcctcctccgggttaccccggcctggagacgatgctgccgctgctg
ctgaccgccgtcagtgatggccgtcttactctggatgacatcatcaagcgtctttatgac
aatccacgcaggatcttcaacctccctgtacaggacaacacctatgtggaggtggacttg
gagcaggagtgggtcattcctcaggccatgcagttcactaagtcgaagtggacacctttc
cagggtctgaaggtgaagggtaaagtccgccgcgtggttcttcgaggagaggtggcctac
atcgacggccaggtgttggtgcctccgggttatggtgaagacgtaaaggcgtggcccgct
gctttgattcatctccctgaacctgtcaaagaaagtccgaagactccagagcactcgcgt
ccaactcctccccgggaagccctggtccgaacccgagcacccagcccccgtcgattggta
ggagagagccgctacctgctgcctcctcgcatccaccgctcctcggatcctggactaacc
ctagagatggttatgctaccagcagcagcagccgctggtgacggttacagccaccctcct
cctctgtccaggctgctgtcccctcagtcaggaccaggactgctacctgctggacagttg
tcccacttccagacctctcctctgctgcacccgctagtgggtcagcacatcctgtctgtc
agacagttcagcaaagagcagatctcgcacctttttaatgttgcccacactttgcgtatg
atggttcagaaggaacgcagcctggatctcctgaagggtaaagtgatggcgtccatgttc
tacgaggtcagcactcgcaccagtagctccttcgcggcggccatgcagcggctcggcggc
tcggtcgtccacttctgcgaatccacctcatcgacgcaaaagggagaatctctggccgac
tctgtccagaccatgagctgctacgccgacatcttggtgctccgacacccaatgcctgga
gccgtggagagtgcatctcgtcattgccgtaagcctgtgatcaacgccggagacggcgtc
ggggagcatccaacccaggcactgctggacgtcttcaccatcagagaggagctggggacc
gtcaacggcatgacgataactatggtcggggatctgaaacacggccgcacggttcattcc
ctcgccaagctgctgacccagtaccgcatcaccctgcgctacgtggctcccaaggacctc
cacatgccggcagagatcatcagctacgtggcctcaaagggcatcagacaggaggagttt
gaaagtatcgaggaagctctgccagagaccgacgtcctctacatgacgaggatccagaag
gagaggttcgcatctgaggaggagtacatgaattgttttggccagttcatcctcacgcct
cacatcatgacggtagccaagaagaagatggtggtgatgcatccgctgccaagagtcaat
gaaatcagtgtggaggtggacacagacccaagggcagcgtatttccgccaagcagagaac
ggcatgtacatccgaatggctctgctggccacgttactgggcagataa

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