Columba livia (rock pigeon): 102087460
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Entry
102087460 CDS
T02912
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
clv
Columba livia (rock pigeon)
Pathway
clv00140
Steroid hormone biosynthesis
clv01100
Metabolic pathways
Module
clv_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
clv_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
clv_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
clv00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
102087460
Enzymes [BR:
clv01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
102087460
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
102087460
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Ortholog
Paralog
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
NmrA
KR
Motif
Other DBs
NCBI-GeneID:
102087460
NCBI-ProteinID:
XP_021148359
LinkDB
All DBs
Position
Unknown
AA seq
377 aa
AA seq
DB search
MSLAGVSCLVTGAGGFLGQRIVRLLLEEEEALAEIRLLDKAFSNEALERFGKFQGKTEVK
ILEGDIRDVMFLHRACQGVSLVIHTASIIDTLGLIEKQLLWEVNVTGTRLLLEACVRCNV
QHFIYTSTIEVTGPNSRGDPIFNGDEDTAYESESKFPYAQSKRLAEDSVLKADGQVLKDG
GTLMTCALRSMYIFGEGCPFLLGHLDKCLLNKNVYLRFSRKEALVNPVYVGNIAWAHVQA
AKALQVPQKAKHIRGQFYYVSDDTPHMSYADLNYELTKDLGFGIEPQLPMPLTMLYYFSL
LLELVSFLLRPFVRYIPSTNRHLVTLLNTPFTFSYRKAQKDFGYTPRYTWEEASQCTGQW
IASMVPQRRQYLKIKAA
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgtccttggctggggtaagctgtctggtgacaggagcaggaggatttcttggccagagg
attgtccgcttgctgttggaagaagaggaggcgctggctgagatccgactgctggacaaa
gcctttagcaatgaagcactcgagaggtttggaaagttccagggtaagactgaggtgaaa
atcctggaaggggacatccgagatgtgatgttcctgcaccgtgcctgtcagggggtctcc
cttgtcatccacacggcttccatcattgacaccttgggcctcatagagaaacagctgctc
tgggaagtcaatgtaacaggtactcggctgctgctggaggcgtgtgtccgctgtaacgtc
cagcacttcatatacacgagtactatagaagtgacaggcccaaacagtagaggtgaccca
attttcaatggtgatgaagatacagcttacgagagtgaatcaaaatttccttatgctcag
agtaagcggctggcagaggattctgtgctgaaagcagatggccaagtgttaaaggatggt
ggcacactgatgacctgtgccctgagatccatgtacatttttggagaaggatgcccattt
ctcctaggccatctggataagtgtctgttgaacaaaaatgtctacctgcgcttctccagg
aaagaggctctggtgaaccccgtgtatgtggggaacattgcctgggcacatgtgcaggca
gccaaagctctgcaggtcccacagaaagccaagcacatcagggggcagttctactacgtc
tcagatgacactcctcatatgagctatgcagatttaaattatgagctgaccaaggacctg
gggtttggaattgagccccagctccccatgcctctgacaatgttgtattacttctcgctc
ctgctggagttggtgagcttcttgctcaggccctttgtcagatacatcccctccaccaac
cgccacctggtcactctactgaacaccccattcaccttctcttatagaaaggcacagaag
gattttggctacacgcctcgctacacctgggaagaggccagtcagtgcactggtcaatgg
attgcctccatggtcccacagagaaggcagtacctgaaaatcaaggctgcctga
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