Cryptococcus neoformans var. grubii H99: CNAG_00117
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Entry
CNAG_00117 CDS
T08175
Name
(RefSeq) delta14-sterol reductase
KO
K00222
Delta14-sterol reductase [EC:
1.3.1.70
]
Organism
cng
Cryptococcus neoformans var. grubii H99
Pathway
cng00100
Steroid biosynthesis
cng01100
Metabolic pathways
cng01110
Biosynthesis of secondary metabolites
Module
cng_M00102
Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Brite
KEGG Orthology (KO) [BR:
cng00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
CNAG_00117
Enzymes [BR:
cng01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.70 Delta14-sterol reductase
CNAG_00117
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Gene cluster
GFIT
Motif
Pfam:
ERG4_ERG24
DUF1295
ICMT
PEMT
Motif
Other DBs
NCBI-GeneID:
23883980
NCBI-ProteinID:
XP_012046180
UniProt:
J9VDZ1
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Position
1:complement(316447..318942)
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AA seq
459 aa
AA seq
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MDAQEESTTTVITATAHLDLPAHPHIKTYQELNPRSKPTEFFGPCGTGAITLFAPLFAYI
FFFACNDAVGCTPTSVQGWKDAFALVGNYPSSAGKLWDWKAAGVYLGWYAFCMICEVVLP
GQKVQGNLLRDGRRKTYRMNGLYTFLLALGLLTGVLVQPRGIQAFTWLHDHFVPLMSASL
AMATFQAVWVYVWSFFSGELLALGGNSGNVVYDFFIGRPLNPTIPGFSSFDIKTFNEVRP
GMILWLLLNISCACEQYVRVGKLTDSMWIVLVFEGWYVLDCLLQEHTILNQMDITTDGFG
FMLAFGDLTWVPFTYGLQARFLASNPVELGPVATALIVGVEIAGMYIFRVANNEKADFRA
GKNPKNLEYMQTERGTKLLTSGWWGRSQHPNYFGDWLIALGWCLPTGFNTPLTYFYLVYF
VILLLHRQKRDEEACKLKYGKDWDRYCEKVPYKIIPYVY
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atggacgcccaggaagaatccacgacgacagtcataacagcaacggcccacctcgacctc
cccgcacacccgcacatcaagacctaccaggagctcaacccacgctcaaagcccacagag
ttcttcggcccatgcggcacaggcgcaatcaccctcttcgcgcctcttttcgcctacatt
ttcttcttcgcctgtaacgatgccgttggatgcacaccaactagtgtccaggggtggaaa
gatgcctttgcactggtaggcaactacccgagctccgcgggtaagttgtgggactggaaa
gctgcgggcgtgtatctcggctggtatgcgttctgtatgatctgtgaagttgtcctgccc
gggcagaaagtccaaggtaacctgctgagagatggtcgacgaaagacctacagaatgaac
ggtctttacacttttctcctcgcccttggtcttcttaccggtgtcttggtccagcccagg
ggtatccaagctttcacttggcttcatgaccactttgtacccctcatgtccgccagtttg
gccatggccactttccaagccgtctgggtctatgtatggagctttttctctggtgagctc
ttggctctcggcgggaactctggtaatgtcgtttacgacttctttatcggccgacctctc
aaccctaccatccccggattttcctctttcgacatcaagacattcaatgaagttcgaccc
ggcatgatcctctggctgttactcaacatttcttgcgcctgcgagcaatacgtcagggtc
ggaaagctgactgatagtatgtggatcgtcctcgtctttgagggctggtacgtcctcgac
tgtctgttgcaagagcacacaatcctcaaccagatggacattacgaccgacggcttcggc
tttatgctcgcctttggcgacctcacctgggtcccttttacctatggccttcaagcgcga
ttcttggcttccaaccccgtggagctgggtcccgtggcgacagcgttgattgtcggtgtc
gagatcgcggggatgtacatctttagagtagctaataatgaaaaggccgatttcagggct
ggaaagaatcccaagaatctggaatacatgcagacggagagaggtaccaagcttttgact
tctggctggtggggccgatctcagcaccccaattactttggcgactggctcattgctctc
ggatggtgtctccccaccggcttcaacacccctctcacatacttttacctcgtctacttt
gttattcttcttttgcacaggcaaaagagggatgaagaggcctgtaaactcaagtatggc
aaagactgggaccgttattgcgaaaaagtgccctacaagattatcccttacgtctattaa
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