Cryptococcus neoformans var. grubii H99: CNAG_04351
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Entry
CNAG_04351 CDS
T08175
Name
(RefSeq) methylmalonate-semialdehyde dehydrogenase (acylating)
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
cng
Cryptococcus neoformans var. grubii H99
Pathway
cng00280
Valine, leucine and isoleucine degradation
cng00410
beta-Alanine metabolism
cng00562
Inositol phosphate metabolism
cng00640
Propanoate metabolism
cng01100
Metabolic pathways
cng01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
cng00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
CNAG_04351
00562 Inositol phosphate metabolism
CNAG_04351
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
CNAG_04351
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
CNAG_04351
Enzymes [BR:
cng01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
CNAG_04351
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
CNAG_04351
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Gene cluster
GFIT
Motif
Pfam:
Aldedh
LuxC
Motif
Other DBs
NCBI-GeneID:
23887786
NCBI-ProteinID:
XP_012051751
UniProt:
J9VRJ7
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Position
9:644446..647209
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AA seq
545 aa
AA seq
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MLSLIRRPIQLRAYTSAAFASTSSNSKLSPLALKAAEDVSSKWRGTTANGGKTKIYIGGE
FLDSKTDKWLEVRDPASQTLINTVPETTPDEFRAAVDAASQSFKTWSKTSIMRRQRAMFE
LQHLIRRHAPEIANSIVLEQGKTYTDALGDVGRGLQVVESATAITSTLLGDKLEVANDMD
TYVRRLPLGVAATISPFNFPAMIVLWSAALATVTGNTLIVKPSERDPGATMIIAELCERA
GIPPGVINVIHGTVPTVNRICDDPAIKAISFVGSDKAGEHIYNRAIVQGKRVQANLGAKN
HAIIMPDANKNLALNSVAGAAFGAAGQRCMALSVAIFVGTAREMIPELIERAKGLKVTGG
FEEGADLGPVISPQAKKRIEDYIGSVEEEGGKILLDGRSYNVSEYPDGSFVGPTIVEAVT
TMKVYKNEVFGPVLTIVEADTLDDAIAIINANKYGNGASIFTNSGSTARKFEVEAEPGQI
GINVAVPVPLPMFGWSGNKASAKGDIPFYGKSGLDFYTYKKTTTSLWPAADAVGNRASVH
MPQIH
NT seq
1638 nt
NT seq
+upstream
nt +downstream
nt
atgctttctctgatcagacgtccaatccagcttagggcgtacacctcagctgccttcgcc
tcaacttcatccaacagtaaactatcgcctcttgcactcaaagcagccgaagatgtctcc
tccaaatggagagggaccacagcaaacgggggaaaaactaagatctatatcggaggggag
tttttggacagcaagactgataaatggctggaagtccgagatcctgcttcccaaaccctc
atcaatacagtcccagaaactacaccagatgaatttagagcagctgtagatgccgctagt
caatctttcaaaacctggtccaagactagcatcatgcgtcgccaacgagcaatgttcgag
ctgcagcatctaattcgtcgacatgccccagagattgccaattccatcgtcttagagcaa
ggaaaaacttatactgatgctctcggtgacgttggtcgcggccttcaagtcgtcgaaagt
gctaccgccatcacatcgaccctactcggggataagcttgaagttgccaacgacatggac
acctacgtccgaagacttcctttgggagttgcagctaccatatccccatttaacttccct
gcaatgatcgtcctctggtctgcagcgcttgcaaccgtcactgggaacacccttattgta
aagccttccgagagagaccctggggctaccatgatcattgcggagctgtgtgagagggcg
ggtattcctcctggagtaatcaatgttatccatgggacagtccctacagttaatagaatc
tgtgatgacccagctatcaaggccatctcttttgtagggagcgacaaagctggcgaacat
atctacaatagggctattgtccagggcaagcgagtgcaggcaaacttgggtgctaaaaat
catgctatcattatgcctgatgcgaacaaaaaccttgctcttaactctgtcgctggtgct
gctttcggtgctgccggtcagcgatgtatggccctgtctgttgcgatctttgtgggcacc
gcccgggagatgatccccgaactcattgaaagagcaaagggcttgaaggtaactggagga
ttcgaggaaggtgcagatctgggacctgtcatttcgccccaggcgaaaaagcgtattgag
gactatataggttcagtggaagaagaaggaggaaagatccttttggacggacgtagttac
aacgtgtccgagtatcctgacggcagctttgtcggtcctaccattgttgaagctgtgact
acaatgaaggtttacaagaacgaggtctttggcccggtcttgaccatcgttgaggccgat
acccttgacgatgctatcgccattatcaacgccaacaaatacggtaacggtgcctctatt
ttcaccaattctggatccactgctcgtaaattcgaggttgaagctgaaccaggacagatc
ggtatcaatgttgctgtacctgttccacttcctatgttcggatggtcaggtaacaaggct
tcagccaagggggacatcccgttctatgggaagagtggtttggatttttacacctataag
aagacaaccacaagtctctggcccgctgctgatgctgttggtaacagagcgagtgtccac
atgccccagattcactga
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