Cryptococcus neoformans var. grubii H99: CNAG_07529
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Entry
CNAG_07529 CDS
T08175
Name
(RefSeq) threonine ammonia-lyase, biosynthetic
KO
K01754
threonine dehydratase [EC:
4.3.1.19
]
Organism
cng
Cryptococcus neoformans var. grubii H99
Pathway
cng00260
Glycine, serine and threonine metabolism
cng00290
Valine, leucine and isoleucine biosynthesis
cng01100
Metabolic pathways
cng01110
Biosynthesis of secondary metabolites
cng01200
Carbon metabolism
cng01230
Biosynthesis of amino acids
Module
cng_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
cng00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
CNAG_07529
00290 Valine, leucine and isoleucine biosynthesis
CNAG_07529
Enzymes [BR:
cng01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.1 Ammonia-lyases
4.3.1.19 threonine ammonia-lyase
CNAG_07529
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Gene cluster
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Motif
Pfam:
PALP
Thr_dehydrat_C
Motif
Other DBs
NCBI-GeneID:
23890367
NCBI-ProteinID:
XP_012048387
UniProt:
J9VIL5
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Position
3:complement(1119292..1121430)
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AA seq
517 aa
AA seq
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MILMSKVYSAPLNLKETPLTYAVNLSARLGNEIWIKREDLQPVFSFKIRGAYNMMASLSD
EEKKKGVITCSAGNHAQGVALSGHALNIPAIVVMPVSTPSIKWRNVQRLGATVVLHGRDF
DEAKAECLRLEKEKGLTFVPPYDNPYVVAGQGTVAMEICRQVTDADQIDGIFASVGGGGL
AAGIAAYMKRVAKPSVRIYGVETVDGDAMDRSLKAGKRVLLDEVGPFADGTAVRLVGEEP
FRVCKNFLDGIVLVNNDEICAAIKDVFEETRSVPEPSGALSLAGLKAHIIRNNLQGAGKR
FVAVISGGNMNFGRLRFVAERADVGERREVLMSVRVPEKPGSFLKFHSLLGSRAVTEFSY
RHSNDSTGYIICSFLLSSSSSSSSGPSPEARAKEIHEMVESFKKHGIEAVDLSEDEFAKS
HVRHLVGGRSAVEHERIFRFEFPERPGALGNFLKGMKVEWNISMFHYRNHGADVGKVLIG
VQVPSQDNPAFDEFLETLGYPYVEETQNEVYTMFLRS
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atgatcttgatgtccaaggtctactcggcccccctcaacctcaaggaaacgcccctcaca
tacgccgtcaacctctccgcccgtctcggcaacgagatctggatcaagcgcgaagacctc
caacccgtattctcattcaagatccgcggcgcttacaacatgatggcgagtctctcggac
gaagaaaagaagaagggtgtcatcacatgctctgccggcaaccacgcacagggcgtcgcc
ctctccggccacgcactcaacatccccgccatcgtcgtcatgcccgtctccaccccctcc
atcaaatggcgcaacgtccagcgtctcggcgccaccgtcgtcctccacggccgcgacttt
gacgaagccaaggccgaatgtctccgcctcgaaaaggaaaaaggcctcaccttcgtcccc
ccttacgacaacccctacgtcgtcgccggccagggaacagtcgccatggaaatctgccgc
caagtcacagatgccgatcaaatcgacggcatattcgcttccgtcggcggaggcggtctt
gcagccggtatcgcagcgtacatgaaacgtgtcgccaaacccagcgtcagaatatacggt
gtcgagaccgtcgacggcgatgccatggaccgttcactcaaggccggaaagagggtcctc
ctcgatgaagttggaccgtttgcagacggcaccgctgtaaggctcgtcggcgaagaacct
tttcgagtttgcaaaaactttttggacggcatcgtgctcgtcaacaatgacgagatttgc
gccgccatcaaggatgtctttgaagaaacccggtccgtccccgaaccgtccggcgccctc
tccctcgcaggtctgaaggcccacattatccgaaacaacctccaaggcgccggtaaacgc
tttgtcgccgtcatctctggcggtaacatgaactttggccgactccgattcgtcgctgag
cgtgccgatgtcggtgagcgacgggaagtgctcatgagtgtccgcgtgcccgaaaagcct
ggcagctttttgaaattccactccctcctcggttcacgggcagtcaccgaattctcctac
cgccactccaacgactctaccggctacatcatctgctccttcctcctctcctcctcatcc
tcttcttcctctggcccctcgcccgaagcgcgcgcaaaggagattcacgagatggtcgag
tcgtttaagaaacatggtatcgaagcggtagatttgagtgaggatgagtttgcaaagagt
catgtgaggcatttggtcggtggacggagtgcggtagagcacgagaggatctttcggttt
gagttcccggaaagaccaggggcacttggaaactttctcaaaggtatgaaggtcgaatgg
aacatttccatgttccactacagaaaccacggcgccgacgtcggcaaagtcctcatcggt
gtccaggtgccatcccaagacaaccccgcatttgacgagtttttggaaacgctcgggtat
ccgtatgtcgaagaaacccagaatgaggtttacaccatgttcctcaggtcgtaa
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