Chionomys nivalis (European snow vole): 130862700
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Entry
130862700 CDS
T11437
Symbol
Irs2
Name
(RefSeq) insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
cnl Chionomys nivalis (European snow vole)
Pathway
cnl04022
cGMP-PKG signaling pathway
cnl04068
FoxO signaling pathway
cnl04081
Hormone signaling
cnl04140
Autophagy - animal
cnl04152
AMPK signaling pathway
cnl04211
Longevity regulating pathway
cnl04213
Longevity regulating pathway - multiple species
cnl04910
Insulin signaling pathway
cnl04920
Adipocytokine signaling pathway
cnl04923
Regulation of lipolysis in adipocytes
cnl04930
Type II diabetes mellitus
cnl04931
Insulin resistance
cnl04932
Non-alcoholic fatty liver disease
cnl04935
Growth hormone synthesis, secretion and action
cnl05010
Alzheimer disease
cnl05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
cnl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
130862700 (Irs2)
04022 cGMP-PKG signaling pathway
130862700 (Irs2)
04152 AMPK signaling pathway
130862700 (Irs2)
09133 Signaling molecules and interaction
04081 Hormone signaling
130862700 (Irs2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
130862700 (Irs2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
130862700 (Irs2)
04923 Regulation of lipolysis in adipocytes
130862700 (Irs2)
04920 Adipocytokine signaling pathway
130862700 (Irs2)
04935 Growth hormone synthesis, secretion and action
130862700 (Irs2)
09149 Aging
04211 Longevity regulating pathway
130862700 (Irs2)
04213 Longevity regulating pathway - multiple species
130862700 (Irs2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
130862700 (Irs2)
09164 Neurodegenerative disease
05010 Alzheimer disease
130862700 (Irs2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
130862700 (Irs2)
04932 Non-alcoholic fatty liver disease
130862700 (Irs2)
04931 Insulin resistance
130862700 (Irs2)
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Gene cluster
GFIT
Motif
Pfam:
IRS
PH
MEKK4_N
Motif
Other DBs
NCBI-GeneID:
130862700
NCBI-ProteinID:
XP_057608418
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Position
20:57208071..57233705
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AA seq
1332 aa
AA seq
DB search
MASAPLPGAPAPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGDDA
AAAGGSPPLPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE
YFAVAAENEQEQEGWYRALTDLVSEGRSGDGGSGTAATGGSCSASLPGVLGGSAGAAGSD
DNYGLVTPATAVYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQ
LMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFR
PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCTSCRV
RTASEGDGGAAAGAGTAGGRPMSVAGSPLSPGPVRAPLSRSHTLSGGCGGRPSKVTLAPA
GGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPLPPGPHPHLPHPLHHPQGQRP
SSGSASASGSPSDPGFMSLDEYGSSPGDLRAFSSHRSNTPESIAETPPTRDGSGGELYGY
MSMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMR
ATFSGSSGRLCPSFPVSSPKVAYHPYPEDYGDIEIGSHKSSSSNLGADDGYMPMTPGAAL
RSVGPSSCKSDDYMPMSPTSVSAPKQILQPRSAAAAALPPSGAAVPAPPSGPGRTFPVNG
GSYKASSPAESSPDDSGYMRMWCGSKLSMENTDPKLLPNGDYLNMSPSEAGTAGTPPDFF
SAALRGGGEGLKGVPGHCYSSLPRSYKAPYCSGDSDQYVLMSSPVGRILEEERLEPQATS
GTSQLAGTFGAAGGGHTQPHHSAVPSSMRPSGGSGRPEGFLGQRCRAVRPTRLSLEGLQT
LPSMQEYPLPSEPKSPGEYINIDFGEAGTRLSPPAPPLLASAASSSSLLSASSPASSLGS
GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPVAHSGDTVGSMDGLLSPEVSSPYPPLPPR
PSASPSSLQQPLPPAPGELYRLPPTSVATSQGPTAGSSTSSEPGDNGDYTEMAFGVAATP
PQPIAAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQVSQPTDPHRGAKVIRADPQGG
RRRHSSETFSSTTTVTPVSPSFAHNSKRHNSASVENVSLRKSSEGSCILGGSDEPPTSPG
QAQPSPAVPPATQARPWNPGQPGALIGCPGGGSSPMRRETSVGFQNGLNYIAIDVRDEQG
SLSPSQPQHPQPGDKSSWGRTRSLGGLLSTVGSTGTGGVCGGPGPGALPSASTYASIDFL
SHHLKEATVVKE
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atggctagcgcgcccctacccggggcccccgcgccggcgggcggggacggcccgaacctc
aataacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggccacaagcgcttcttcgtgctgcgaggccccggcacgggaggcgacgatgca
gccgcggctggggggtcgccgccgctgccaccgaggctggagtactatgagagcgagaag
aagtggaggagcaaggcgggcgcgccgaagcgagtgatcgcgctcgactgctgcctgaac
atcaacaagcgcgcggacgctaagcacaagtacctgatcgccctctacaccaaggacgag
tacttcgccgtggcggcggagaacgagcaggagcaagagggctggtaccgcgcgctcacc
gacttggtcagcgagggtcgctctggcgatgggggctcgggcaccgcggccaccggcggg
tcctgcagcgcctctctcccgggcgtcctgggcggctcggcgggtgccgctggctccgat
gacaactacgggctcgtgacgcctgccacggcagtctaccgcgaggtgtggcaggtgaac
ctgaagcccaagggcctgggtcagagcaaaaacctgactggtgtataccgtctatgtctg
tctgctcgcaccatcggcttcgtgaagctcaattgcgaacagccgtcggtgacgctgcag
cttatgaacattcgccgctgcggccactcagacagcttcttcttcatcgaagtgggccgc
tcggccgtcaccggccccggcgagttgtggatgcaagccgacgactcggtggtggcgcag
aacatccacgagaccatcctggaggccatgaaggcgctcaaggagctctttgagttccgg
cctcgcagcaagagtcaatcgtccgggtcgtcggccacgcaccccatcagtgtgccgggc
gcgcgccgccaccaccacctggtcaacctgccccctagccagaccggcctggtgcgccgc
tcacgcaccgacagcctggcggccaccccgccagcagccaagtgcacctcgtgtcgggtc
cgtacggccagcgagggcgacggcggcgcggcagccggggccgggacagcgggaggcagg
ccgatgtcggtggccgggagccccctgagtcctgggccggtgcgcgcgcccctgagtcgc
tcgcacaccctgagcggcggctgcggaggccgcccgagcaaagtgacgctggcgccggca
gggggcgccctacaacacagccgttccatgtccatgcccgtggcgcactcacctccagct
gccaccagccccggcagcctatcctccagcagtgggcacggctcgggctcctacccgctg
cctccaggcccccacccgcacctgcctcatccgctgcaccacccccaaggccagcgtccg
tccagcggcagtgcctctgcctccggctcccccagtgaccctggtttcatgtcccttgat
gagtatggctccagccctggcgacctgagagctttcagtagccacaggagcaacacaccc
gagtcaatcgcggagaccccgccaaccagggacggcagtgggggcgagctctatgggtac
atgagcatggatagacccctgagccactgtggccgcccttaccgtagggtctctggggat
ggggcccaggacctggacagagggctgaggaagaggacttattccttgaccacacctgcc
cgacagcggccagtaccccagccttcctctgcctcccttgatgagtatactctcatgcgg
gcaaccttctctggcagttcaggtcgcctctgcccatccttccccgtgtcttctcccaaa
gtggcctatcacccttacccagaggactatggagacattgagattggctcccacaagagt
tccagcagtaacctgggggcagatgatggttacatgcccatgacccctggggctgccctc
aggagtgttggccccagtagctgcaagagtgatgactacatgcccatgagccccaccagc
gtgtctgcccccaagcagatcctgcagcccaggtcagcggcagcggcagccttgccaccc
tcgggagctgcagtgccagcacccccttcagggccaggcaggaccttccccgtgaacgga
ggcagctacaaagccagctccccagccgagagctctccggatgatagcgggtacatgcga
atgtggtgtggctccaagctgtccatggagaacacagacccaaagctgctccccaacggg
gactacctcaacatgtcccccagcgaggctggcaccgcgggcacgccacccgacttcttc
tcagcagctttgcgtggagggggagagggcctcaagggtgtccctggacactgctacagc
tctctgccccgctcttacaaggccccctattgtagtggggacagtgaccaatatgtgctc
atgagctcccctgtggggcgaatcttggaagaggagaggctggaaccccaggccacctct
ggaacctcccagttggctggcacctttggggcagctgggggtggccatacccagcctcac
cactcagcagtgccttcttccatgaggccgagtggcggcagtggccgccctgagggcttc
ctgggccagcgctgtcgggcagtacgacccacgcgcttgtcactggagggactgcagacc
cttcccagcatgcaagagtaccctttaccctcagagcccaagagccctggagagtatatc
aacattgactttggtgaggcgggtacccgtctgtccccgcctgcccccccactgctggca
tcagcagcttcatcctcttcgttgctttcagccagtagtcctgcttcatccctgggttca
ggtaccccaggcaccagcagtgacagccggcagcgctccccgctctctgactatatgaac
ttggacttcagttctcccaagtcccctaaacctgtcgcccatagtggagacacagtaggc
tccatggatggccttctctccccagaggtctcatctccatacccacctctgcccccacgt
ccttctgcctccccctcttccctgcaacagcctctgccacctgccccaggagagctctac
cgcctgcctccaacatcagttgccacttcccagggccccactgctggctcctcaacatcc
tcagagcctggggataatggtgactataccgagatggcctttggtgtggctgctaccccg
ccacaacctatcgcagcacccccaaagccagaaggtgcccgagtgaccagtcccacatct
ggcttgaagcgcctaagtctcatggatcaggtgtctggggtggaggcgtttcttcaagtc
agccagcccactgatccccaccggggtgccaaggtcatccgtgcagacccacaggggggg
cgacgtcgccacagctcagagaccttctcctccaccaccacagtcaccccagtgtccccc
tccttcgcccacaactctaagcgccacaattcagcctctgtggaaaacgtctctctcagg
aaaagcagtgaaggtagttgcatcctgggaggaagtgatgagccgcccacatccccagga
caggcacagccatcgccggctgtgccaccagccacgcaggctaggccatggaacccaggt
caacctggggctttgattggctgtcctggaggtggcagttctcccatgcgcagagagacc
tctgtgggtttccagaacggcctcaactacatcgccattgacgtgagggatgagcagggg
tccctgtcgccatctcagccgcagcacccacagcctggagacaagagttcctggggccgg
acccgtagccttgggggacttctcagcaccgtgggaagcactggcaccggcggggtgtgt
gggggcccaggccccggagccttgccctctgccagcacctacgcaagcattgacttcttg
tcccaccacttgaaagaagccacagttgtgaaagagtga
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