Cupriavidus oxalaticus: E0W60_07490
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Entry
E0W60_07490 CDS
T06004
Symbol
mdeB
Name
(GenBank) alpha-ketoglutarate dehydrogenase
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
cox
Cupriavidus oxalaticus
Pathway
cox00010
Glycolysis / Gluconeogenesis
cox00020
Citrate cycle (TCA cycle)
cox00620
Pyruvate metabolism
cox00785
Lipoic acid metabolism
cox01100
Metabolic pathways
cox01110
Biosynthesis of secondary metabolites
cox01120
Microbial metabolism in diverse environments
cox01200
Carbon metabolism
cox01210
2-Oxocarboxylic acid metabolism
Module
cox_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cox00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
E0W60_07490 (mdeB)
00020 Citrate cycle (TCA cycle)
E0W60_07490 (mdeB)
00620 Pyruvate metabolism
E0W60_07490 (mdeB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
E0W60_07490 (mdeB)
Enzymes [BR:
cox01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
E0W60_07490 (mdeB)
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
PDH_E1_N
Transketolase_N
Transketolase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
QBY50986
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Position
1:complement(1669355..1672057)
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AA seq
900 aa
AA seq
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MTNLANGVQSMLALPSANEDSDPQETREWLDALEGVLAHAGSARASFLLRRLAAHAAAQG
LPPPGAGPSAYVNTIPVQAQPPYPGDLEIEARLGAALRWNALAMVVRANRAYGELGGHIA
SYASAADLFEVGFNHFFRGDSAEQGGDLVYFQPHSAPGVYARAYLEGFLDETHLQHYRRE
IGGPGLCSYPHPWLMRDFWQFPTGSMGIGPINSIYQARFMRYLQNRGLQPASSRKVWGFF
GDGEMDEPESIGALSLAAREQLDNLVFVINCNLQRLDGPVRGNGRIVDELEALFAGAGWN
VIKVLWGSDWDELFARDRSGALVRAFAQTVDGQFQTFSANDGAYNREHFFQQNPELAALA
AHLSNDDIDRLRRGGHDLRKLHAAYTRAMGHRGQPTVILAKTMKGFGMGTAGQGRMTTHQ
QKKLELEDLKAFRDRFQLPLSDDDVANLRFYKPADDSPEMRYLHARRAALGGYLPRRRQA
ATTALTVPPSGQWAGFALAADGKEMSTTMAVVRMLGSLLKDTALGPRIVPVVADEARTFG
MANLFRQVGIYSPLGQRYEPEDLGSMLYYRESTGGQILEEGISEAGAISSWIAAATAYSV
HDLPMLPFYIYYSMFGFQRIGDLIWAAADQRARGFLIGATSGKTTLGGEGLQHQDGTSHL
AASTIPNCRAWDPAFAYEVAVIVEHGMREMGEQQRDVFYYVTVGNENYAQPSMPQPADAV
RDGILKGMYSLTPERRDASQVDLLGAGAILPEVIAAARLLEDDWGVVAQVWSVTSFTELQ
RDAIAVERSNRLNDQHARSYVETALAGSNGPVIAATDYVRAVPELIRACVPGRYVTLGTD
GFGRSDTRQALRAFFEVDRHSVVVAALRALADDGKLPSDVVRAARERYGKSGDKAASWQA
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccaacctggcaaacggtgtgcaatcgatgctcgcgctgccttcggccaacgaggac
agcgatccccaggaaacgcgcgaatggctggacgcgctcgaaggcgtgctggcgcatgcc
ggcagcgcgcgcgccagcttcctgctgcggcgcctggcggcgcatgccgcagcgcagggc
ctgccgccgcccggcgccggcccgagcgcctatgtgaataccatccccgtgcaggcgcag
ccgccctaccctggcgacctggagatcgaagcccggctgggcgccgcgctgcgctggaat
gcgttggccatggtggtgcgcgccaaccgcgcctatggcgaactgggcggccatatcgcc
agctatgcctccgcggccgatctgttcgaagtcggattcaaccacttcttccgcggcgac
agcgccgaacagggcggcgacctggtctacttccagccgcactcggcccccggcgtctac
gcccgcgcctacctggagggtttcctcgacgagacccacctgcagcactaccggcgcgag
atcggcgggccgggcctgtgctcctacccgcatccctggctgatgcgggacttctggcag
ttcccgaccggctcgatgggcatcggccccatcaattcgatctaccaggcgcgcttcatg
cgctacctgcagaaccgcgggctgcagccggcgtcgtcgcgcaaggtctggggcttcttc
ggcgatggcgagatggacgagcccgagtcgatcggcgcattgtcgctggccgcgcgcgag
cagctcgacaacctggtcttcgtcatcaactgcaacctgcagcggctcgacgggcccgtg
cgcggcaacggccgcatcgtcgatgagctcgaagcgctgttcgccggcgccggctggaac
gtgatcaaggtgctgtggggctcggactgggacgagctgttcgcccgcgaccgctccggc
gcgctggtgcgggccttcgcgcagaccgtcgacggccagttccagaccttctccgccaac
gacggcgcctacaaccgcgagcatttcttccagcagaaccccgagctcgccgcactcgcc
gcgcacctgagcaacgacgacatcgaccgcctgcgccgcggcggccacgacctgcgcaag
ctgcacgccgcctacacacgcgccatgggccaccgcggccagcccaccgtgatcctggcc
aagaccatgaagggcttcggcatgggcacggctggccaggggcgcatgaccacgcaccag
cagaagaagctggagctggaagacctgaaggccttccgcgaccgcttccagctgccgctg
tcggacgacgacgtcgccaacctgcgcttctacaaacccgccgacgacagcccggaaatg
cgctacctgcacgcacgccgggccgcgctcggcggctacctgccgcggcgccggcaggcc
gcgaccaccgcgctcacggtgccgccgtccggccagtgggccggcttcgcactggccgcg
gacggcaaggaaatgtcgaccaccatggccgtggtgcgcatgctcggcagcctgctcaag
gacaccgcgctggggccgcgcatcgtgccggtggttgctgacgaggcacgcaccttcggc
atggccaacctgttccggcaggtcggcatctattcgccgctgggccagcgctatgagccg
gaagacctgggttcgatgctgtactaccgcgaatccaccggcgggcagatcctggaagaa
ggcatctccgaagccggcgcgatctcgtcatggatcgccgcggccaccgcctacagcgtg
cacgacctgccgatgctgcccttctacatctactactcgatgttcggcttccagcgcatc
ggcgacctgatctgggccgctgccgaccagcgcgcccgcggcttcctgatcggcgccacc
tcgggcaagaccacgctcggcggcgaggggctgcagcaccaggacggcaccagccacctg
gccgcgtcgaccatccccaactgccgcgcgtgggatcccgcctttgcctatgaagtggca
gtgatcgtggagcatggcatgcgcgagatgggcgagcagcagcgcgacgtcttctactac
gtcaccgtcggcaacgagaactatgcgcagccgtcgatgccgcagccggccgatgccgtg
cgcgacggcatcctgaagggcatgtactcgcttacgcccgaacggcgcgatgccagccag
gtcgacctgctcggcgcgggcgccatcctgcccgaggtgatcgccgccgcgcgcctgctc
gaagacgactggggcgtggtggcgcaggtctggagcgtgaccagtttcaccgagctgcag
cgcgacgcgatcgccgtggaacgcagcaaccgcctgaacgaccagcatgcccgctcgtat
gtcgaaacagcgctggcagggtcgaacggcccggtgatcgccgccaccgattatgtgcgc
gcggtgccggagctgatccgcgcgtgcgtgccggggcgctatgtcacgctgggcaccgac
ggcttcgggcgcagcgacacgcggcaggcgttgcgcgcgttcttcgaggtggaccgccat
tctgtcgtggtcgcggcgctgcgggcgctggccgatgacggcaagctgccttccgatgtc
gtgcgcgcggcgcgggagcgctatggcaagtcgggggacaaggccgcgtcgtggcaggcg
tga
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