Cupriavidus pauculus: EHF44_26225
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Entry
EHF44_26225 CDS
T05738
Symbol
mdeB
Name
(GenBank) alpha-ketoglutarate dehydrogenase
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
cpau
Cupriavidus pauculus
Pathway
cpau00010
Glycolysis / Gluconeogenesis
cpau00020
Citrate cycle (TCA cycle)
cpau00620
Pyruvate metabolism
cpau00785
Lipoic acid metabolism
cpau01100
Metabolic pathways
cpau01110
Biosynthesis of secondary metabolites
cpau01120
Microbial metabolism in diverse environments
cpau01200
Carbon metabolism
cpau01210
2-Oxocarboxylic acid metabolism
Module
cpau_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cpau00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
EHF44_26225 (mdeB)
00020 Citrate cycle (TCA cycle)
EHF44_26225 (mdeB)
00620 Pyruvate metabolism
EHF44_26225 (mdeB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EHF44_26225 (mdeB)
Enzymes [BR:
cpau01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EHF44_26225 (mdeB)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
AZG16858
UniProt:
A0A3G8H942
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All DBs
Position
2:1813109..1815784
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AA seq
891 aa
AA seq
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MQAQPIDPTDLIPSSGHHPDDADRQETGEWLDALAGVARQGGAERVGFLLRRLAEHASHL
GMAPSAHPYQLYQNTIALEEQPAYPGDLAMEERITSILRWNALAMVARANKAYGELGGHI
ASYASAAEIFEIGFNHFFRADSEAGKGDLVYFQPHSAPGVYARAFLEGRLDEAQLGRYRQ
EVNGGGLCSYPHPWLMPEFWQFPTGSMGIGPISAIYQARFLRYLEHRGIAPTAGRRVWGV
FGDGEMDEPESIAALSLAAREKLDNLTFVINCNLQRLDGPVRGNGQIIQELESLFAGAGW
NVIKVVWGSDWDALFARDHHHALLRRFAETVDGQYQTLGANDGAYNRAHFFDLDPELRAL
VSHMTPEEIDGLRRGGHDFRKLYAAFDAARRHAGRPTVILAKTKKGYGMGQAGESRNTSH
QQKKLDVDALRAYRDRFQLPLSDEAVETMQFLKPGDDSPELRYLQARRAALGGYLPRRVT
TAPAVPVPGLESYAQFALQPDGREVSTTTAVVRLFTNLLKDKTLGPRIVPIVADEARTFG
MANLFRQVGIYSPHGQLYEPEDAGSMLYYKESRDGQLLEEGITEAGAVSSWTAAATSYSV
NGVAMLPFYIYYSMFGFQRIGDLIWAAADQRARGFLIGATAGRTTLSGEGLQHQDGTSHL
IASTIPNCRAWDPAFAGEAAVIIDHGARRMLEQQQDEFHYLTVTNENYAQAPIDPAQHAD
ILRGMRLHATTGSGQPQVRLLGSGAILREVIAAAHTLADDWGIAAEVWSVTSFSELARAT
QEAQRLRVFSAGTVTPSHLETCLAGDTPVVAATDYVRAYANLIAPYVRAPYTALGTDGFG
RSDTRAALRSFFEVDQRHIVLAALAAVDAEKHRAALACDGATDPKPAPWHC
NT seq
2676 nt
NT seq
+upstream
nt +downstream
nt
atgcaagcccaacccatcgatccgaccgacttgatcccttcgagcggccaccaccccgac
gacgccgaccgccaggaaaccggcgaatggctcgacgccctggctggcgtggcccgccag
ggcggcgccgaacgcgtgggctttctgctgcgccggcttgccgagcacgccagccatctg
ggcatggcaccatcagcccatccgtaccagctctaccagaacacgattgcgctggaagag
cagccggcctatccgggcgacctggcgatggaggagcgcatcacgtccatcctgcgatgg
aacgcgctggcgatggtcgcgcgcgccaacaaggcgtatggcgaactgggcggacatatc
gccagctacgcgtcggcagccgaaatcttcgagatcggcttcaaccacttcttccgcgcc
gacagcgaagcgggcaagggcgacctcgtctacttccagccgcattccgcgcccggcgtc
tacgcgcgcgccttccttgaggggcgtctggacgaggcgcaactgggccgctatcggcaa
gaggtcaatggcggcggattgtgttcgtacccgcacccgtggctgatgccggagttctgg
cagtttcccaccggttcgatgggcatcggcccgatcagcgcgatctaccaggcgcggttc
ctgcgctacctggaacatcgtggcatcgcgcccacggccgggcgccgcgtgtggggcgtg
ttcggggatggcgagatggacgaacccgagtcgatcgccgcgctgtcgcttgccgcgcgc
gagaagctggacaacctgacgttcgtcatcaactgcaacctgcagcggctggacgggccg
gtgcgaggcaatggccagatcatccaggagctggaatcgctgttcgccggcgcgggctgg
aacgtcatcaaggtggtctggggatcggactgggacgcgctgttcgcgcgcgaccatcac
cacgcgctgctgcgccgctttgccgaaacggtcgacggtcagtaccagacgctgggtgcc
aacgatggcgcctacaaccgcgcgcatttcttcgacctcgatccggaactgcgggcgctg
gtgtcgcacatgacgccagaggagatcgacggcctgcgccgcggcggccatgacttccgc
aagctgtacgcagccttcgatgccgcccggcgccacgccggccggccgaccgtgatcctg
gccaagaccaagaagggctacggcatggggcaggcgggcgagtcgcgcaacacttcgcac
cagcagaagaagctcgacgtggatgcgctgcgcgcgtaccgcgaccgctttcagttgccg
ctgagcgacgaggccgtcgagaccatgcagttcctgaagccgggcgacgacagcccggaa
ctgcgctacctgcaggcgcgccgcgcagcgcttggcggctatctgccacgccgggtaacg
acggcgcccgcggtgccggtgccggggctggagagctacgcgcaattcgcgctgcagccc
gatggccgcgaggtgtccaccaccaccgccgtagtgcgcctgttcaccaacctgctgaag
gacaagacgctgggcccgcgcatcgtgcccatcgttgcggacgaggcgcgcacgttcggc
atggccaacctgttccggcaggtcggcatctattcgccgcatggccagctctacgagccc
gaggacgcgggctcgatgctctactacaaggaatcccgcgacgggcaactgctggaggaa
ggcattaccgaggcgggcgcggtgtcatcgtggacggcggccgccacgtcgtacagcgtc
aacggcgtggcgatgctgccgttctacatctattactcgatgttcggcttccagcgcatc
ggcgacctgatctgggccgcggccgaccagcgtgcgcgcggcttcctgatcggtgccacc
gccgggcgcacgacgctgtcgggtgagggcctgcagcatcaggacggcaccagccacctg
attgcgtcgaccattcctaactgccgcgcctgggaccccgcctttgcaggcgaggccgcc
gtcatcatcgatcacggtgcgcgccgcatgctcgaacagcagcaggacgagtttcactac
ctgaccgtcaccaacgagaactacgcgcaggcgcccatcgatccggcgcagcacgccgac
atcctgcgcggcatgcgcctgcatgcgacaacgggcagcggccagccccaagtgcggctg
ctgggctcgggggcgatcctgcgcgaggtcatcgccgccgcccatacgctggccgacgac
tggggcattgccgccgaagtctggagcgtgacgagcttctccgaactcgcccgcgcgacg
caggaggcgcagcgtctgcgcgtgttctcggccggcaccgtgacacccagccatctggag
acctgcctggcaggcgacacgccggtagtggccgccaccgactacgtacgcgcctacgcc
aacctgatcgcgccctacgtccgggcgccgtacaccgcgctgggtaccgatggattcggc
cgtagcgacacgcgggcggccctgcgcagcttcttcgaggtggaccagcgccatatcgtg
ctggcggcgctggccgccgtcgacgcggagaagcatcgggccgccctggcgtgcgacggt
gccaccgatccgaagcccgcgccgtggcattgctga
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