Cavia porcellus (domestic guinea pig): 100135490
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Entry
100135490 CDS
T07777
Symbol
Cacna1c
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc04010
MAPK signaling pathway
cpoc04020
Calcium signaling pathway
cpoc04022
cGMP-PKG signaling pathway
cpoc04024
cAMP signaling pathway
cpoc04260
Cardiac muscle contraction
cpoc04261
Adrenergic signaling in cardiomyocytes
cpoc04270
Vascular smooth muscle contraction
cpoc04713
Circadian entrainment
cpoc04720
Long-term potentiation
cpoc04723
Retrograde endocannabinoid signaling
cpoc04724
Glutamatergic synapse
cpoc04725
Cholinergic synapse
cpoc04726
Serotonergic synapse
cpoc04727
GABAergic synapse
cpoc04728
Dopaminergic synapse
cpoc04742
Taste transduction
cpoc04911
Insulin secretion
cpoc04912
GnRH signaling pathway
cpoc04921
Oxytocin signaling pathway
cpoc04924
Renin secretion
cpoc04925
Aldosterone synthesis and secretion
cpoc04927
Cortisol synthesis and secretion
cpoc04929
GnRH secretion
cpoc04930
Type II diabetes mellitus
cpoc04934
Cushing syndrome
cpoc04935
Growth hormone synthesis, secretion and action
cpoc05010
Alzheimer disease
cpoc05020
Prion disease
cpoc05022
Pathways of neurodegeneration - multiple diseases
cpoc05031
Amphetamine addiction
cpoc05207
Chemical carcinogenesis - receptor activation
cpoc05410
Hypertrophic cardiomyopathy
cpoc05412
Arrhythmogenic right ventricular cardiomyopathy
cpoc05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100135490 (Cacna1c)
04020 Calcium signaling pathway
100135490 (Cacna1c)
04024 cAMP signaling pathway
100135490 (Cacna1c)
04022 cGMP-PKG signaling pathway
100135490 (Cacna1c)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100135490 (Cacna1c)
04929 GnRH secretion
100135490 (Cacna1c)
04912 GnRH signaling pathway
100135490 (Cacna1c)
04921 Oxytocin signaling pathway
100135490 (Cacna1c)
04935 Growth hormone synthesis, secretion and action
100135490 (Cacna1c)
04924 Renin secretion
100135490 (Cacna1c)
04925 Aldosterone synthesis and secretion
100135490 (Cacna1c)
04927 Cortisol synthesis and secretion
100135490 (Cacna1c)
09153 Circulatory system
04260 Cardiac muscle contraction
100135490 (Cacna1c)
04261 Adrenergic signaling in cardiomyocytes
100135490 (Cacna1c)
04270 Vascular smooth muscle contraction
100135490 (Cacna1c)
09156 Nervous system
04724 Glutamatergic synapse
100135490 (Cacna1c)
04727 GABAergic synapse
100135490 (Cacna1c)
04725 Cholinergic synapse
100135490 (Cacna1c)
04728 Dopaminergic synapse
100135490 (Cacna1c)
04726 Serotonergic synapse
100135490 (Cacna1c)
04720 Long-term potentiation
100135490 (Cacna1c)
04723 Retrograde endocannabinoid signaling
100135490 (Cacna1c)
09157 Sensory system
04742 Taste transduction
100135490 (Cacna1c)
09159 Environmental adaptation
04713 Circadian entrainment
100135490 (Cacna1c)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100135490 (Cacna1c)
09164 Neurodegenerative disease
05010 Alzheimer disease
100135490 (Cacna1c)
05020 Prion disease
100135490 (Cacna1c)
05022 Pathways of neurodegeneration - multiple diseases
100135490 (Cacna1c)
09165 Substance dependence
05031 Amphetamine addiction
100135490 (Cacna1c)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100135490 (Cacna1c)
05412 Arrhythmogenic right ventricular cardiomyopathy
100135490 (Cacna1c)
05414 Dilated cardiomyopathy
100135490 (Cacna1c)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100135490 (Cacna1c)
04934 Cushing syndrome
100135490 (Cacna1c)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
cpoc04040
]
100135490 (Cacna1c)
Ion channels [BR:
cpoc04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100135490 (Cacna1c)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
Motif
Other DBs
NCBI-GeneID:
100135490
NCBI-ProteinID:
NP_001166394
UniProt:
O35505
LinkDB
All DBs
AA seq
2169 aa
AA seq
DB search
MVPLVQPTTPAYRPLPSHLSADTEVRGRGTLVHEAQLNCFYISPGGSNYGSPRPAHANIN
ANAAAGLAPEHIPTPGAALSWQAAIDAGRQAKLMGSAGNTTISTVSSTQRKRQQYGKPKK
QSGTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDD
SNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAI
LEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHT
ALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGITDVPAEEDPSPCALESGHGRQCQNGTV
CKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIF
GSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPEN
EDEGVDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNR
FCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEM
LLKMYSLGLQAYFVSLFNRLDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT
RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMRTRRSTFDN
FPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAI
AVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVVEKPAVEETKEEKIELKSITA
DGESPPTTKINMDDLQPNENEDKSPYPNPDAAGEEDEEEPEMPVGPRPRPLSELHLKEKA
VPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNH
ILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAI
NVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLF
KGKLYTCSDSSKQTEAECKGNYITYKDGEVDQPIIQPRSWENSKFDFDNVLAAMMALFTV
STFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQE
QGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILL
NTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIV
VGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLW
TFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFR
CATGEAWQDIMLACMPGKKCAPESDPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLF
VAVVMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFG
KLCPHRVACKRLVSMNMPLNSDGTAMFNATLFALVRTALRIKTEGNLEQANEELRAIIKK
IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL
QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFGRAGGLFGNHVSYYQ
SDSRSTFPQTFTTQRPLHINKAGNNQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN
NTALGRFPHPAGYPSTVSTVEGHRPPSSPATWAQEATRKLGAMRCHSRESQIAVVCQEEP
SQDKTYDVELNKDAEYCSEPSLLSTEMLSYKDDENRQLTPPEEDKGDTRPSPKKGFLRSA
SLGRRASFHLECLKRQKNHGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPTAIPRP
CATPPATPGSRGWPPKPIPTLRLEGAESCEKLNSSFPSIHCSSWSEEPSPCGGGSSAARR
ARPVSLMVPSQAGAPGRQFHGSASSLAEAVLISEGLGQFAQDPKFIEVTTQELADACDMT
IGEMENAADNILSGGAPQSPNGTLLPFVNCRDPGQDRAGGDEDEGCACALGRGWSEEELA
DSRVHVRSL
NT seq
6510 nt
NT seq
+upstream
nt +downstream
nt
atggtaccccttgttcagcccaccacacctgcataccggccactgcccagtcacctgtct
gcggacacagaggtgaggggtagaggcaccttggtgcacgaagctcagctcaactgcttc
tacatctctcccggaggttccaactatggcagcccacgcccagctcatgccaacataaat
gccaatgcggctgcagggctggcccctgagcacatccccaccccgggggcagccctatcc
tggcaggcagccatcgatgcgggccggcaggccaagctgatgggcagtgctggaaatacc
accatctccactgtcagctctacacagcggaagcggcagcagtatgggaaacctaagaag
cagagtggcacaactgccacgcggccgcctcgggccctgctctgcctaactctgaagaac
cctatccggagagcatgcattagcattgttgaatggaaaccatttgaaataattatttta
ctgactatttttgccaattgtgtggccttagcaatctatattccctttccagaagatgat
tccaacgctaccaattccaacctggaacgagtggaatatctctttctcataatttttact
gtggaagcatttttaaaagttatcgcctatggacttctctttcaccccaatgcttacctc
cgcaatggttggaatttactagattttatcattgtggttgtagggctttttagtgcaatt
ttagaacaagcaaccaaagcagatggggcaaatgctctaggagggaaaggcgctggattt
gatgtgaaagcgctgagggctttccgtgtgctgcgcccgctgcgactggtgtctggagtc
ccaagtctccaggttgtcctgaactccattatcaaggccatggtgcccctgctgcacact
gccctgctcgtgctgtttgtcatcatcatctatgcgatcatcggcctggagctcttcatg
gggaagatgcataagacgtgctacaaccaggagggcatcacagatgtcccagcagaagag
gacccctccccctgtgctcttgagagcggccacgggagacaatgccagaatggcacagtg
tgcaagcccgggtgggacgggcctaagcacggcatcaccaacttcgacaactttgccttc
gccatgctcaccgtgttccagtgcatcaccatggagggctggaccgacgtgctgtactgg
atgcaggacgctatgggctatgagttaccctgggtgtattttgtcagtctggtcatcttt
ggatcctttttcgttctaaatctggttctcggtgtgttgagcggagagttttccaaagag
agggagaaggccaaggctcggggagatttccaaaagctccgagagaaacagcagctggaa
gaggatctcaaaggctaccttgactggatcacccaggcagaagacattgaccccgagaat
gaggatgaaggcgtggatgaggagaagccccgaaacatgagcatgcccaccagcgagacc
gagtccgtcaacactgaaaacgtggctggaggtgacatcgagggagagaactgtggggcg
aggctggcccaccgaatctccaaatcaaagttcagccgctactggcgcagatggaaccgg
ttctgcagaaggaagtgccgggctgccgtcaagtccaatgtcttctactggctggtgatc
ttcctggtgttcctcaacacgctcactattgcctccgaacattacaaccagccccactgg
ctcacagaagtgcaagacacagccaataaagctctcctggccctttttactgcggagatg
ctcctgaagatgtacagtctgggcctgcaggcctacttcgtgtccctcttcaaccgcctc
gactgcttcatcgtgtgtgggggcatcctggagaccatcctggtggagaccaagatcatg
tctcccttaggcatctctgtgctgagatgtgtccggctcctgaggatatttaaaatcaca
aggtactggaactccttaagcaacctagtggcatccttgctgaactctgtgcgctccatt
gcctccctgctcctgctcctcttcctctttatcatcatcttctccctgttggggatgcag
ctctttggagggaagttcaactttgatgagatgcgaacccggaggagcacgtttgataac
ttcccccagtcccttctaactgtgtttcagatcctgaccggggaggactggaattcggtg
atgtatgatgggatcatggcttatggcggcccctcttttccagggatgttagtctgtatt
tacttcatcatcctcttcatctgtggaaattatatcctactgaatgtgttcttggccatt
gctgtggacaacctggctgatgctgagagcctcacttctgcccaaaaggaggaagaagaa
gagaaggagagaaaaaagctggccaggactgccagcccagaaaagaaacaggaggtggtg
gagaagccagcagtggaggagactaaagaggagaaaatcgagctgaaatccattaccgct
gatggagagtccccacccaccaccaagatcaacatggatgacctccagcccaatgaaaat
gaggacaagagtccctaccccaaccccgatgctgcaggagaagaggatgaggaggagcct
gagatgcctgtcgggccccgtccgcggccactctctgagctgcaccttaaggaaaaagcc
gtgcccatgccagaagccagcgcattcttcatcttcagccctaacaacaggtttcgcctg
cagtgccaccgcattgtcaatgacacgatcttcaccaacctgatcctcttcttcattctg
ctcagcagcatttctctggccgcagaggaccccgtacaacacacctccttcaggaaccat
attctgttttattttgatattgtttttactaccattttcaccattgaaattgctctgaag
atgacagcttatggggcttttctacacaagggctctttctgccggaattacttcaacatc
ttggacctactggtggtcagcgtgtccctcatctcctttggcatccagtccagtgcaatc
aatgtggtgaagatcttgcgagtgctgcgcgtcctccggcccctgagggccatcaacagg
gctaaagggctaaagcatgtggtccagtgcgtgtttgttgccatccggaccatcgggaat
atcgtcattgtcaccacactgctgcagttcatgttcgcctgcatcggggtccagctcttc
aagggaaaactctacacctgttctgatagttccaagcaaacagaagcagaatgcaagggg
aactacatcacatacaaagatggggaggttgaccagcctattatccagccccgcagctgg
gaaaacagcaagtttgacttcgacaatgtcctggcagccatgatggccctcttcactgtc
tccacgtttgaggggtggccagagctgctgtaccgctccatcgactcccacacggaagac
aagggtcccatctataactaccgcgtggagatctccatcttcttcatcatctacatcatc
atcattgccttcttcatgatgaacatcttcgtgggtttcgtcatcgtcaccttccaggag
cagggagagcaggagtacaagaactgcgagctggacaagaaccagcgacagtgtgtggag
tacgccctcaaggcccggcccctgcggcggtacattcccaagaaccagcaccagtacaag
gtgtggtatgtggtcaactccacctactttgagtacctgatgtttgtcctcatcctgctc
aacaccatctgcttggccatgcagcactatggccagagctgcctgttcaaaatcgccatg
aacatcctgaacatgctcttcaccggcctcttcactgtggagatgatcctgaaactcatt
gccttcaaacccaagcactatttctgtgatgcatggaatacatttgacgccttgattgtt
gtgggtagcattgttgatatagcaatcaccgaggtaaacccagctgaacatacccaatgc
tctccctctatgaacgcagaagaaaactcccgcatctccatcaccttcttccgcctcttc
cgggtcatgcgtctggtcaagctgctgagccgcggggagggcatccggacactgctgtgg
accttcatcaagtcctttcaggccttgccctacgtggcccttctgatagtaatgctgttc
ttcatctatgccgtgattggtatgcaggtgtttggaaagattgccttgaacgacaccacg
gagatcaaccggaacaacaactttcagactttcccccaagccgtgctgctgctgttcagg
tgtgccacaggggaggcctggcaggacatcatgctggcctgcatgccgggcaagaagtgt
gctccggagtccgaccccagcaacagcacagaaggggagacaccctgtggcagcagcttt
gctgtcttctacttcatcagcttctacatgctttgtgccttcctgatcatcaacctcttt
gtagctgtcgtcatggacaactttgactacctgacaagagactggtcaatcctcggtccc
caccatctggatgaatttaaaagaatctgggcagaatatgacccagaagccaagggtcgt
atcaaacacctggatgtggtcacccttctccgacggattcagcctcctctgggttttggg
aagctgtgtcctcatcgagtggcctgcaagcgccttgtctccatgaacatgcctctgaac
agcgatgggaccgccatgttcaatgccaccctgtttgccctggtcaggacagccctgagg
atcaaaacggaagggaacctagaacaagccaatgaggagctgcgcgccatcatcaagaag
atctggaaacggaccagcatgaagcttctggaccaagtggtgccccctgctggtgatgac
gaggtcacagttggcaagttctacgctactttcctgatccaagagtacttccggaagttc
aagaagcgcaaagagcaagggcttgtgggcaagccctcccagaggaatgctctgtctcta
caggctggcttgcgcaccctacatgacattggacctgagatccgccgagccatctctgga
gacttgactgccgaggaagagctagacaaggccatgaaggaggctgtgtctgctgcctcc
gaagatgacatcttcgggagggcgggtggcctgttcggcaaccatgtcagctactaccaa
agcgacagccggagcaccttcccccagaccttcaccacccagcgcccactgcacatcaac
aaggcgggtaacaaccaaggcgacactgagtcaccctcccacgagaagttggtagactcc
accttcacccccagcagctactcgtccactggctccaacgccaacatcaacaacgccaac
aacactgccctgggccgcttcccccaccccgccggctaccccagcacggtcagcaccgtg
gagggccacaggcccccctcatctcctgccacctgggcgcaggaggccacgaggaagctc
ggcgccatgaggtgccactcccgggagagccagatagccgtagtgtgtcaggaggagccc
tctcaggacaagacctatgacgtggagctgaataaagatgctgagtactgcagcgagccc
agcctgctctccacagagatgctgtcctataaggatgatgaaaatcgacaactgacaccg
cctgaggaagacaagggggacacccggccctctccaaagaagggtttcctccgctccgcc
tccctaggtcgaagagcctccttccacctggagtgtttaaagcgccagaagaatcatggg
ggtgacatttctcagaagacagtcctacccttgcatctggttcatcatcaggcactggcc
gtggcgggcctgagccctctcctccagagaagccattccccgaccgccatccccaggccg
tgtgccacaccccctgccacgccgggcagccgaggctggcccccgaaacccatccccacc
ctgcggctagagggcgccgagtcctgcgagaaactcaacagcagcttcccgtccatccac
tgcagctcgtggtcagaggagcccagcccctgcggcgggggcagcagcgcggcgcggaga
gcccggcccgtgtccctcatggtgcccagccaggccggggccccggggagacagttccac
ggcagtgccagcagcctggcggaggcggttttgatttcagaaggactgggacagtttgct
caagatcccaagttcatcgaggtcacaacccaggagctggctgacgcctgcgatatgacc
ataggggagatggagaacgcggcagacaacatcctcagcgggggggccccgcagagtccc
aacggcacccttttacctttcgtgaactgcagggacccagggcaggaccgggcaggcggt
gacgaggacgagggctgtgcatgcgccctggggcgcggctggagcgaggaggagctcgcg
gacagcagggtccacgtccgcagcctgtag
DBGET
integrated database retrieval system
