Cavia porcellus (domestic guinea pig): 100712946
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Entry
100712946 CDS
T07777
Symbol
Erbb3
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc01521
EGFR tyrosine kinase inhibitor resistance
cpoc04010
MAPK signaling pathway
cpoc04012
ErbB signaling pathway
cpoc04020
Calcium signaling pathway
cpoc04151
PI3K-Akt signaling pathway
cpoc05205
Proteoglycans in cancer
cpoc05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100712946 (Erbb3)
04012 ErbB signaling pathway
100712946 (Erbb3)
04020 Calcium signaling pathway
100712946 (Erbb3)
04151 PI3K-Akt signaling pathway
100712946 (Erbb3)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100712946 (Erbb3)
05205 Proteoglycans in cancer
100712946 (Erbb3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100712946 (Erbb3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cpoc01001
]
100712946 (Erbb3)
Enzymes [BR:
cpoc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100712946 (Erbb3)
Protein kinases [BR:
cpoc01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100712946 (Erbb3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
TM_ErbB1
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100712946
NCBI-ProteinID:
XP_003476244
Ensembl:
ENSCPOG00000014852
LinkDB
All DBs
Position
Unknown
AA seq
1336 aa
AA seq
DB search
MRASGALQVLGFLLSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRHPDAEIVVQDNG
RSCPPCHEACKGRCWGPGPEDCQTLTKTICAPQCNGHCFGPDPNQCCHDECAGGCSGPQD
TDCFACRHFNDSGACVPLCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTS
CVRACPPDKMEVNKNGINMCEPCGGLCPKACEGTGAGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNVTSLGLRSLKEISAGRIYISANRQLCYHHSLNWTRLLRGPAED
RLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGQGPGQCLSCRNYSRGGVCVTHCNFLNGEP
REFAYEAECFSCHPECQPMEGMATCNGSGSDACVQCAHFRDGPHCVSSCPHGVLGAKGPI
FKYPDVRNECRPCHENCTQGCKGPQLQDCLGQPLVLISKTHLALTVTVGLTVILLVLGIT
FLYWRGRRIQNKRAMRRYLERGESLEPLDPSEKANKVYARIFKETELRKLKVLGSGVFGT
VHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSS
LQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHSMVHRNLAARNVLL
KSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVW
ELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELA
NEFTRMARDPPRYLVIRRDSGSGIPPGAEPSTLTNKELEEVELEPELDLDSDLEAEEDSL
ATTLGSALSLSAGTLTRPRGSQSLLSPSSGYMPMNQSNLGEAPQESAVCGDSERCPRPVS
LHPVPRARLASESSEDHVTGCDTELQEKVSMCRSRSRSPRPRGDSAYHSQRHSLLTPVTP
LSPPGLEEEDVNGYVMPDTHLKGTSSSQEGTLSSVGLSSVLGTEEEDEDEEYEYMNRRRR
HSLPRPPRPGSLEELGYEYMDVGSDLSASLGSTQSCPLHPVPIIPTAGTTPDEDYEYMNR
QRGSGTGGDYAAMGACPAAEQGYEEMRAFQGPGHNAPHVRYARLKTLRSLEATDSAFDNP
DYWHSRLFPKANAQRT
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
atgagggccagtggggctctgcaggtgctgggcttccttctcagcctggcccggggctcg
gaggtgggcaactcgcaggcagtgtgccctgggactctgaacggactgagtgtgacaggc
gatgctgagaatcaataccaaacactatacaagctctatgaaaggtgtgaggtggtgatg
gggaacctggaaattgttctcactggacacaatgcggacctctctttcttacagtggatt
cgagaagtgacaggctatgtcctcgtggccatgaacgaattctctacactccccttgcct
aacctgcgagtggtgcgggggacccaggtctacgatgggaagtttgccatctttgtcatg
ttgaactataacaccaactccagccatgctctgcgccagctccgttttacccagctcaca
gagatcctgtcagggggtgtttatattgagaagaatgataaactttgtcacatggacaca
attgactggcgggatattgtgaggcacccagacgctgagatagtggtgcaggacaatggc
agaagctgtcccccatgtcacgaggcctgcaagggacgttgctggggccctggaccagag
gactgccaaacattgacaaagactatctgtgcccctcaatgtaacggtcactgctttggg
ccggaccccaaccagtgctgccatgatgagtgtgcaggcggttgctctggccctcaggac
accgactgctttgcctgccgacacttcaacgacagcggagcctgtgtgcccctgtgccca
cagcctcttgtgtacaacaagctcactttccagctcgaacccaatccccacaccaaatac
cagtatggtggagtttgtgtagccagctgtccccataacttcgtggtggatcagacatcc
tgtgtccgggcatgtcctcctgacaagatggaagtaaataaaaatggcatcaacatgtgt
gaaccttgtggagggttgtgtcctaaagcctgtgaagggacaggtgctgggagtcgcttc
cagactgtggactcgagcaacatcgatgggtttgtgaactgcaccaagatcctgggcaac
ctagactttctgatcactggactcaatggagacccttggcacaagatccctgccttagac
cctgagaagctcaatgtgttccggacagtacgggagatcacaggttacttgaacatccag
tcctggcctccacacatgcacaacttcagtgttttttccaatctgacaaccattgggggc
agaagtctctacaaccggggtttctcactattgataatgaagaatttgaatgttacatcc
ctgggcctccgatccctaaaagagataagcgctggtcgtatctacatcagtgccaatcgg
cagctctgctaccatcactctctgaactggaccaggctgcttcgggggcctgcagaagac
aggctggacatcaagcataatcggccccgcagggactgtgtggcagagggcaaagtgtgt
gacccgctgtgctcctccgggggatgctggggccaaggccctgggcagtgcttgtcctgt
cgaaactacagccgagggggtgtctgtgtgacccactgcaactttctgaatggggagcct
cgtgagtttgcctatgaagctgaatgcttttcctgccacccagaatgccagcccatggag
ggcatggccacgtgcaatggctcgggctctgatgcttgtgttcagtgtgcccattttcga
gacgggccccactgtgtgagcagttgcccccatggagtcctaggtgccaaaggtcctatc
ttcaagtacccagatgttcggaatgaatgtcggccctgccatgagaactgcacccagggg
tgtaagggaccacagctacaagactgtttgggtcaaccactggtactaatcagcaaaacc
catttggcattgactgtgacagttggattgacagtgattttactggtcctgggcatcact
tttctctattggcgtgggcgcaggattcagaataaaagggctatgaggcgctacttggaa
cggggtgagagcttagaacctctggatcctagtgagaaggctaacaaagtctatgccaga
atcttcaaagagacagaactgaggaagcttaaagtgcttggttcaggggtctttggaaca
gtgcacaaaggagtgtggatccctgaaggtgaatccatcaagattccagtctgcattaaa
gtcattgaggacaagagtggacggcagagttttcaagctgtgacagatcatatgctcgcc
attggcagcttagaccatgcccatattgtacggctgctaggactttgcccaggatcatct
ctgcagcttgtcactcaatacttgcctctgggttccctattggatcatgtgagacaacac
cgcggggcactggggcctcagctgctgctcaactggggagtacaaattgccaagggtatg
tactacctagaggagcacagtatggtgcataggaatctggctgcccgaaatgtgctgctt
aagtcacccagtcaggttcaagtcgcagattttggtgtggctgacctgctgccacctgat
gacaagcagctgctacacagtgaggccaagactccaattaagtggatggcccttgagagt
attcacttcgggaaatacacacaccagagtgacgtctggagctatggcgtgacagtttgg
gagctgatgacctttggggcagagccctatgctgggctgcgactggctgaagtaccagac
ctgctggagaagggggagcggctggcacagcctcagatctgcaccattgatgtctacatg
gtcatggtcaagtgttggatgattgatgagaatattcgtccgacctttaaagaactagcc
aatgagttcaccaggatggcccgtgatccaccacggtatctagtcataaggagagacagt
gggtctggaatacctcctggggcagagccctctactctgacaaacaaggaactagaagaa
gtagagctagagccagaactggaccttgactcagacttggaggcagaggaagacagcctg
gcaaccacgctaggttctgccctcagcttatcagctggaacacttacccggccacgaggg
agccagagccttttaagcccatcatctggatacatgcccatgaaccaaagtaacctcggg
gaagccccccaggagtctgcagtttgtggggatagtgaacggtgcccccgtcctgtctct
ttacacccagtgccacgggcacgcctggcatcagaatcatcagaggaccatgtgacaggc
tgtgacactgagctccaagagaaggtgtcaatgtgtagaagccggagccggagcccacgg
ccacgcggagacagtgcctaccattcccagcgccatagcctgcttactcctgtcacccca
ctctcccctccgggcttagaagaagaggatgtcaacggttatgtcatgccagacacacat
cttaaaggcacttcttcctcccaggaaggtaccctttcttcagtgggtctcagttctgtc
ctgggtactgaagaagaagatgaagatgaagagtatgaatacatgaaccggaggagaagg
catagtctacctcgtccccctaggcctggttccctcgaggagctgggttatgagtacatg
gatgtaggatcagacctcagtgcctctctgggtagcacacagagttgcccactccatcct
gttcccatcatacccactgctggcaccactcctgatgaggactatgaatatatgaatcgg
cagcgtggaagtggtacagggggggattatgcagccatgggggcctgcccagcagctgaa
caaggctatgaagagatgagagctttccaggggcctggacacaatgccccccatgttcgc
tatgcccgcctcaaaactctacgaagcttagaagccactgactcggcctttgataatcct
gactactggcatagcaggcttttccctaaggctaatgcccagagaacataa
DBGET
integrated database retrieval system
