KEGG   Cavia porcellus (domestic guinea pig): 100715453
Entry
100715453         CDS       T07777                                 
Symbol
Grb2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc01521  EGFR tyrosine kinase inhibitor resistance
cpoc01522  Endocrine resistance
cpoc04010  MAPK signaling pathway
cpoc04012  ErbB signaling pathway
cpoc04014  Ras signaling pathway
cpoc04062  Chemokine signaling pathway
cpoc04068  FoxO signaling pathway
cpoc04072  Phospholipase D signaling pathway
cpoc04150  mTOR signaling pathway
cpoc04151  PI3K-Akt signaling pathway
cpoc04380  Osteoclast differentiation
cpoc04510  Focal adhesion
cpoc04540  Gap junction
cpoc04550  Signaling pathways regulating pluripotency of stem cells
cpoc04630  JAK-STAT signaling pathway
cpoc04650  Natural killer cell mediated cytotoxicity
cpoc04660  T cell receptor signaling pathway
cpoc04662  B cell receptor signaling pathway
cpoc04664  Fc epsilon RI signaling pathway
cpoc04714  Thermogenesis
cpoc04722  Neurotrophin signaling pathway
cpoc04910  Insulin signaling pathway
cpoc04912  GnRH signaling pathway
cpoc04915  Estrogen signaling pathway
cpoc04917  Prolactin signaling pathway
cpoc04926  Relaxin signaling pathway
cpoc04935  Growth hormone synthesis, secretion and action
cpoc05034  Alcoholism
cpoc05160  Hepatitis C
cpoc05161  Hepatitis B
cpoc05163  Human cytomegalovirus infection
cpoc05165  Human papillomavirus infection
cpoc05200  Pathways in cancer
cpoc05203  Viral carcinogenesis
cpoc05205  Proteoglycans in cancer
cpoc05206  MicroRNAs in cancer
cpoc05207  Chemical carcinogenesis - receptor activation
cpoc05208  Chemical carcinogenesis - reactive oxygen species
cpoc05210  Colorectal cancer
cpoc05211  Renal cell carcinoma
cpoc05213  Endometrial cancer
cpoc05214  Glioma
cpoc05215  Prostate cancer
cpoc05220  Chronic myeloid leukemia
cpoc05221  Acute myeloid leukemia
cpoc05223  Non-small cell lung cancer
cpoc05224  Breast cancer
cpoc05225  Hepatocellular carcinoma
cpoc05226  Gastric cancer
cpoc05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100715453 (Grb2)
   04012 ErbB signaling pathway
    100715453 (Grb2)
   04014 Ras signaling pathway
    100715453 (Grb2)
   04630 JAK-STAT signaling pathway
    100715453 (Grb2)
   04068 FoxO signaling pathway
    100715453 (Grb2)
   04072 Phospholipase D signaling pathway
    100715453 (Grb2)
   04151 PI3K-Akt signaling pathway
    100715453 (Grb2)
   04150 mTOR signaling pathway
    100715453 (Grb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100715453 (Grb2)
   04540 Gap junction
    100715453 (Grb2)
   04550 Signaling pathways regulating pluripotency of stem cells
    100715453 (Grb2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100715453 (Grb2)
   04660 T cell receptor signaling pathway
    100715453 (Grb2)
   04662 B cell receptor signaling pathway
    100715453 (Grb2)
   04664 Fc epsilon RI signaling pathway
    100715453 (Grb2)
   04062 Chemokine signaling pathway
    100715453 (Grb2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100715453 (Grb2)
   04912 GnRH signaling pathway
    100715453 (Grb2)
   04915 Estrogen signaling pathway
    100715453 (Grb2)
   04917 Prolactin signaling pathway
    100715453 (Grb2)
   04926 Relaxin signaling pathway
    100715453 (Grb2)
   04935 Growth hormone synthesis, secretion and action
    100715453 (Grb2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100715453 (Grb2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100715453 (Grb2)
  09159 Environmental adaptation
   04714 Thermogenesis
    100715453 (Grb2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100715453 (Grb2)
   05206 MicroRNAs in cancer
    100715453 (Grb2)
   05205 Proteoglycans in cancer
    100715453 (Grb2)
   05207 Chemical carcinogenesis - receptor activation
    100715453 (Grb2)
   05208 Chemical carcinogenesis - reactive oxygen species
    100715453 (Grb2)
   05203 Viral carcinogenesis
    100715453 (Grb2)
   05231 Choline metabolism in cancer
    100715453 (Grb2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100715453 (Grb2)
   05225 Hepatocellular carcinoma
    100715453 (Grb2)
   05226 Gastric cancer
    100715453 (Grb2)
   05214 Glioma
    100715453 (Grb2)
   05221 Acute myeloid leukemia
    100715453 (Grb2)
   05220 Chronic myeloid leukemia
    100715453 (Grb2)
   05211 Renal cell carcinoma
    100715453 (Grb2)
   05215 Prostate cancer
    100715453 (Grb2)
   05213 Endometrial cancer
    100715453 (Grb2)
   05224 Breast cancer
    100715453 (Grb2)
   05223 Non-small cell lung cancer
    100715453 (Grb2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    100715453 (Grb2)
   05160 Hepatitis C
    100715453 (Grb2)
   05163 Human cytomegalovirus infection
    100715453 (Grb2)
   05165 Human papillomavirus infection
    100715453 (Grb2)
  09165 Substance dependence
   05034 Alcoholism
    100715453 (Grb2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100715453 (Grb2)
   01522 Endocrine resistance
    100715453 (Grb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cpoc04131]
    100715453 (Grb2)
Membrane trafficking [BR:cpoc04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    100715453 (Grb2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 DUF7145 SH2_2 DUF5093 hSH3 SH3_4 DUF7063
Other DBs
NCBI-GeneID: 100715453
NCBI-ProteinID: XP_004999347
Ensembl: ENSCPOG00000038564
UniProt: A0A286Y265
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgcagatgatgagctgagcttcaaa
aggggggacatcctcaaggttttgaatgaagaatgtgatcagaattggtataaggcagag
ctcaacgggaaggatggcttcatccccaagaactacatagagatgaaaccacacccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcatgat
ggggcctttctaatccgggaaagtgagagtgctcctggggatttctccctctccgtgaag
tttggaaatgatgtgcagcacttcaaggtgctccgtgatggagcgggaaagtatttcctc
tgggtggtgaagttcaattctctgaatgagctggtagattaccacagatcgacatccgtg
tccagaaaccagcagatattcctccgggacatagaacaggtgccacagcagcccacatac
gtccaggccctctttgactttgacccccaggaggacggcgagctgggcttccgccgggga
gacttcatccacgtcatggataactcagaccccaactggtggaagggtgcttgccacggg
cagaccggcatgtttccccgcaactatgttacccctgtgaaccggaatgtctag

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