Cavia porcellus (domestic guinea pig): 100722979
Help
Entry
100722979 CDS
T07777
Symbol
Map3k5
Name
(RefSeq) LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc01524
Platinum drug resistance
cpoc04010
MAPK signaling pathway
cpoc04071
Sphingolipid signaling pathway
cpoc04141
Protein processing in endoplasmic reticulum
cpoc04210
Apoptosis
cpoc04530
Tight junction
cpoc04668
TNF signaling pathway
cpoc04714
Thermogenesis
cpoc04722
Neurotrophin signaling pathway
cpoc04932
Non-alcoholic fatty liver disease
cpoc04936
Alcoholic liver disease
cpoc05010
Alzheimer disease
cpoc05012
Parkinson disease
cpoc05014
Amyotrophic lateral sclerosis
cpoc05016
Huntington disease
cpoc05017
Spinocerebellar ataxia
cpoc05022
Pathways of neurodegeneration - multiple diseases
cpoc05208
Chemical carcinogenesis - reactive oxygen species
cpoc05417
Lipid and atherosclerosis
cpoc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100722979 (Map3k5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100722979 (Map3k5)
04668 TNF signaling pathway
100722979 (Map3k5)
04071 Sphingolipid signaling pathway
100722979 (Map3k5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
100722979 (Map3k5)
09144 Cellular community - eukaryotes
04530 Tight junction
100722979 (Map3k5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
100722979 (Map3k5)
09159 Environmental adaptation
04714 Thermogenesis
100722979 (Map3k5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
100722979 (Map3k5)
09164 Neurodegenerative disease
05010 Alzheimer disease
100722979 (Map3k5)
05012 Parkinson disease
100722979 (Map3k5)
05014 Amyotrophic lateral sclerosis
100722979 (Map3k5)
05016 Huntington disease
100722979 (Map3k5)
05017 Spinocerebellar ataxia
100722979 (Map3k5)
05022 Pathways of neurodegeneration - multiple diseases
100722979 (Map3k5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100722979 (Map3k5)
05418 Fluid shear stress and atherosclerosis
100722979 (Map3k5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100722979 (Map3k5)
04932 Non-alcoholic fatty liver disease
100722979 (Map3k5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100722979 (Map3k5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cpoc01001
]
100722979 (Map3k5)
Enzymes [BR:
cpoc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
100722979 (Map3k5)
Protein kinases [BR:
cpoc01001
]
Serine/threonine kinases: STE group
STE11 family
100722979 (Map3k5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Pkinase_fungal
Kinase-like
SAM_2
Motif
Other DBs
NCBI-GeneID:
100722979
NCBI-ProteinID:
XP_003468553
Ensembl:
ENSCPOG00000004244
LinkDB
All DBs
Position
Unknown
AA seq
1336 aa
AA seq
DB search
RASSLPTAAASGAAFWNVDSAAAPAXGCPAAAPGSNAARCRGNSSSGGGRRTTVAYVINE
ASQGQLVVAESEALQSLREACEAVGATLETLHFGKLDFGETAVLDRFYNADIAVVEMSDA
FRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNYTFIPYMVSP
HNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLMDRFIQLLKVAQASSSQYFRESILND
IRKARNLYTGKELAAELTRIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEK
LPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVESKGQVASDMYCLVGRIYKD
MFLDSNFTDTESRDHGASWYKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKL
SSLLGKKGNLEKLQSYWEVGFFLGASVLANDHLRVIQASEKLFKLKTPAWYLKSIVETIL
IYKHFVKLTAEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINN
EVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCT
ELHCKKFFEMVNTITEEKGRSVEEGDCDSDSLEYDYEYDENGDRVVLGKGTYGIVYAGRD
LSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPG
GSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLK
ISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTMIEMATGKP
PFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLTDEFLK
VSSKKKKTQPKLSALSAGSNAEYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKVDPFSF
KTRAKSCGEKDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRIL
TEDQDKIVRNLMECLAQGAEEPKLKWEHITTLIVSLREFVRSTDRKIIASTLSKLKLELD
FDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHF
SLASESDTADPEDLDVEEEHEEPPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAH
RSLSVQLGRMKIETNRLLEELVQKEKELQAFLHQAIEEKEQEIKHLKLKYQPIDIPELLV
CHPNPPHRNTDNSELTDWLRQNGADEDTISRFLDEKYTLVDVLYYVTRDDLKYLRLRGGM
LCTLWKAIIDFRNKHI
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
agggcgagctcgctgcccaccgccgccgccagcggggcagctttctggaacgtggacagc
gctgcagccccggccnctgggtgtcctgccgccgcccctgggagcaacgccgcccggtgc
cggggcaactcctcgagcggtggcgggcgccggaccaccgtggcatacgtgatcaacgag
gcgagccaggggcagttggtggtggccgagagcgaggctttgcagagcctgcgagaggct
tgtgaggctgtgggcgctactctggagaccttgcattttggcaaactagacttcggggaa
accgcggtgctggaccgtttttacaacgcagatattgctgtggtggagatgagtgatgcc
ttccgccaaccctccctgttttaccatcttggcgtgagggaaagcttcagcatggccaac
aacatcatcctctactgtgataccaactccgactctctgcagtccctgaaggaaatcatc
tgccagaagaatactatgtgcactgggaactatacctttatcccttacatggtgagcccg
cataataaggtctactgctgtgacagcagcttcatgaagggcttgacggagctcatgcag
cccaacttcgagctgcttctggggcccatctgcttaccactcatggaccggttcatccag
cttttgaaggtggcgcaagcaagttccagccagtacttccgggaatctatactgaatgat
atcaggaaagctcgaaatttatacactggtaaagaattggcagctgaattgacaagaatt
cggcagcgagtagataacattgaagtcttgacagcagacattgtcatcaatctattgctt
tcctacagagatatacaggactatgattccattgtgaagctggtagagactttagaaaaa
ctgccaacctttgatttggcctcccatcaccatgtgaagtttcattatgcatttgcgctg
aataggagaaatctccctggagacagagcaaaagcacttgatattatgattcctatggtg
gaaagcaaaggacaagttgcttcagatatgtattgcctcgttggtcgaatctacaaagac
atgtttttagactctaatttcactgacactgaaagtagagaccatggagcttcttggtac
aaaaaggcatttgaatctgaaccaacactacagtcaggaattaattatgcagtccttctc
ctggcagctggacaccagtttgaatcttcctttgagcttcggaaagttggggtgaagcta
agtagccttcttggtaaaaagggaaacttggaaaaactccagagctactgggaagttgga
ttttttcttggggccagtgtgctggccaatgaccatctgagagtcattcaagcatctgaa
aagcttttcaaactaaagacaccagcatggtacctcaagtcaattgtagagacaattttg
atatacaagcattttgtgaagctgactgcagagcagcctgtggccaagcaagaacttgtg
gacttttggatggatttccttgttgaagccacaaaaacagatgttactgtagttagattt
ccagtgttaatcctggaaccaaccaaaatatatcagccttcttacttgtctatcaacaat
gaagtcgaggaaaagacaatctctatttggcatgtgcttcctgatgacaagaaaggtata
catgagtggaattttagtgcttcctctgtcagaggagtgagtatttctaaatttgaagag
cgatgctgctttctttatgtgcttcacaattctgatgacttccaaatctatttctgtaca
gaacttcactgtaaaaagtttttcgaaatggtgaacacaattaccgaggagaaggggaga
agtgtagaggaaggagactgtgacagtgactccctggagtatgactatgaatatgatgaa
aatggtgacagagtcgttttaggaaaaggcacttacggaattgtctacgcgggtcgggac
ttaagcaaccaagtcagaattgctattaaagaaatcccagagagagatagcagatactct
cagcccctgcatgaagaaatagccttgcataagcatctgaagcacaaaaatattgtccag
tatctgggctctttcagtgagaatggcttcattaaaatcttcatggagcaggtcccagga
ggaagtctttctgctctccttcgttccaaatggggtccattaaaagacaatgagcaaaca
attggcttttacacaaagcaaatactggaaggattaaaatacctccacgacaatcagata
gttcaccgggatataaagggcgacaatgtattgattaatacctacagtggtgttctcaag
atctctgatttcgggacatcaaagaggcttgctggcataaacccatgcaccgaaaccttt
actggtacccttcagtacatggcaccagaaataatcgataaaggaccacgaggctacggc
aaagcagcagatatttggtctttgggctgcacaatgattgaaatggccacaggaaaacca
ccattttatgaactaggagaaccacaagcagccatgttcaaggtggggatgtttaaagtt
caccctgagattccagagtccatgtctgcagaagccaaggcattcatattgaagtgtttt
gaaccagaccctgacaagagagcctgtgctaatgacttacttacagatgagttcttaaaa
gtttccagcaaaaagaaaaagacacaacctaagctttcagctctatcagctggatcgaat
gctgagtacctccgcagcatttccttgccagtgcccgtcctagtggaagacaccagcagc
agcagcgagtacggctctgtttcccctgacacggagttaaaggtggatcccttctctttc
aaaaccagagccaaatcctgtggagaaaaagatgtgaaaggaatacggacactgttttta
ggcattccagatgaaaactttgaagatcacagcgctccaccttcccctgaagaaaaagac
tctggattctttatgctgcggaaggacagtgagaggagagccacgttgcacagaatcctg
acagaagaccaagacaagattgtgcggaatttaatggagtgtttagctcagggtgctgaa
gaacctaaactaaaatgggagcacattacaaccctcattgtgagcctcagagagtttgtg
agatctacagaccggaagatcatagcctctacactgtcaaagctgaaattagagctggac
ttcgacagccatggtatcagccaagtgcaggtggtcctctttggtttccaagatgcggtc
aataaagttcttcggaatcataacatcaagccgcactggatgttcgccttagacagcatc
atacgaaaggctgtacaaacagccattaccattctggttccagagctgaggccgcatttt
agccttgcatcagagagtgacaccgctgatccggaagacttggatgtagaggaagagcac
gaggaaccaccttccaatcaaacagtccgaagaccccaggctgtcattgaagatgctgtt
gccacctcaggggtgagcacactgagctccactgtgtctcatgattctcagagtgctcac
cgatcactgagtgtgcagcttggaaggatgaaaatagaaactaatagactactggaagaa
ttggttcagaaagaaaaagaattacaagccttccttcatcaagccattgaagaaaaagag
caagaaattaagcacctgaagctgaagtaccagccaatagatatccctgagttgctagta
tgtcacccgaatcctccacaccgaaacactgataattctgagctcacagactggctgaga
caaaatggagctgatgaagacactataagtcggtttttggatgagaagtatacactagtg
gacgttctctactacgttacacgtgatgatctaaaatacctgagactaaggggagggatg
ctctgcacactgtggaaggccatcattgactttcgaaacaaacacatttga
DBGET
integrated database retrieval system
