Cavia porcellus (domestic guinea pig): 100724288
Help
Entry
100724288 CDS
T07777
Symbol
Itch
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc04120
Ubiquitin mediated proteolysis
cpoc04144
Endocytosis
cpoc04330
Notch signaling pathway
cpoc04668
TNF signaling pathway
cpoc04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100724288 (Itch)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
100724288 (Itch)
04668 TNF signaling pathway
100724288 (Itch)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100724288 (Itch)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100724288 (Itch)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cpoc04131
]
100724288 (Itch)
04121 Ubiquitin system [BR:
cpoc04121
]
100724288 (Itch)
Enzymes [BR:
cpoc01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
100724288 (Itch)
Membrane trafficking [BR:
cpoc04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
100724288 (Itch)
Ubiquitin system [BR:
cpoc04121
]
Ubiquitin ligases (E3)
HECT type E3
100724288 (Itch)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
100724288
NCBI-ProteinID:
XP_005002784
Ensembl:
ENSCPOG00000013787
UniProt:
H0VPJ7
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGSQPGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLQFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLIGDKEPTETIGDLSICLDGLQLEAEVVTNGETTCAESASQNDDGSRLKDETRVNTNGS
DDPEDAGSGENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNTNTSEGATSGLIIPLTISGGSGPRPLNTVTQAPLPPGWEQRVDQHGR
VYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFAASQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLSMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKQVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIIWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaacctggttcaatgggtagcctgaccatgaaatcacagctg
cagatcactgtcatctcagcaaaacttaaagaaaataaaaagaattggttcggaccaagt
ccttatgtggaagtaacagtagatggacagtcaaagaagaccgaaaaatgcaataatacg
aatagccccaaatggaagcagccacttacagttatcgttacacctgtgagtaaattacag
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatatatgaaacattaaagtcaaacaatatgaaacttgaagaagtggttgtgactttg
cagcttataggtgacaaagagccaacagagacaataggagacttgtcaatctgtcttgat
gggctgcagttagaggcagaagttgttactaatggggaaaccacatgtgcagaaagtgct
tcacagaatgatgatggctctagactcaaagatgaaacaagagtgaacacaaatggatca
gatgaccctgaagatgcaggatctggtgaaaacaggagagtcaatgggaacaattctcct
tcactgtcaaatggtggtttcaagccttctagacctccaagaccctcacgaccacctcca
cccacccctcgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
ggatctagtacaggttctctgccaccaacgaacacaaatacaaatacatctgaaggagca
acttctggattaataatccctcttactatatctggaggctcaggccctaggccattaaat
actgtaactcaagctcccctaccacctgggtgggaacagagagttgaccagcatgggcga
gtttattatgtagatcatgttgaaaaaagaacaacatgggatcgacctgaacctctacct
cctggttgggaacggcgggttgacaatatgggacgtatttattatgttgaccattttaca
agaacaacaacatggcagaggccaactttagaatctgtccggaactacgagcagtggcag
ctacaacgtagtcaactgcaaggagcaatgcagcagtttaaccagagattcatttatggg
aatcaagatttgtttgctgcatcacaaaataaagaatttgatcctcttggtcctttgcca
cctggatgggagaagagaactgatagcaatggcagagtgtattttgtgaatcacaacact
cgaattacacagtgggaagaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtggatggaattccatactttgtggaccacaataga
agaacaactacctatatagatccccgcacaggaaaatctgctctagacaatggaccgcag
atagcctatgttcgggacttcaaggcaaaggttcagtattttcgcttctggtgtcagcaa
ctgtccatgccacagcacataaaaattacagtaacaagaaaaacattatttgaggattcc
tttcagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttacagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggaagatttatcgccatggctcttttccatgggaaattcatagacacaggtttttcttta
cccttctacaaacgtattctgaacaaacaagttggacttaaggatttagaatctattgat
ccagaattttacaattctctcatctgggtgaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgttgataaagaaatactaggtgaaattaaaagtcatgatttaaaa
cccaatggtggcaatattcttgtaacagaagaaaacaaagaggaatacatcagaatggta
gctgagtggagattgtctcgaggtgttgaagaacagacacaagctttctttgaaggtttt
aatgaaattcttccgcagcagtatttgcagtactttgatgcaaaggaattagaggtcctt
ttatgtggcatgcaagaaattgatttgaatgactggcaaagacatgccatctatcgtcat
tatactaggacaagcaaacaaatcatatggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttactggaacctgccgattgccagtaggagga
tttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaag
gaaaattggttacccagaagtcatacctgttttaaccgcctggaccttccaccctacaag
agctatgagcaattgaaggaaaagctgttgtttgccattgaagaaacagaaggatttgga
caagagtaa
DBGET
integrated database retrieval system
