Cavia porcellus (domestic guinea pig): 100728089
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Entry
100728089 CDS
T07777
Symbol
Acacb
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc00061
Fatty acid biosynthesis
cpoc00620
Pyruvate metabolism
cpoc00640
Propanoate metabolism
cpoc01100
Metabolic pathways
cpoc04152
AMPK signaling pathway
cpoc04910
Insulin signaling pathway
cpoc04920
Adipocytokine signaling pathway
cpoc04922
Glucagon signaling pathway
cpoc04931
Insulin resistance
cpoc04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100728089 (Acacb)
00640 Propanoate metabolism
100728089 (Acacb)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100728089 (Acacb)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100728089 (Acacb)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100728089 (Acacb)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100728089 (Acacb)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100728089 (Acacb)
04931 Insulin resistance
100728089 (Acacb)
Enzymes [BR:
cpoc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100728089 (Acacb)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100728089 (Acacb)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100728089 (Acacb)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
100728089
NCBI-ProteinID:
XP_003477800
Ensembl:
ENSCPOG00000004635
LinkDB
All DBs
Position
Unknown
AA seq
2457 aa
AA seq
DB search
MVFLLFLSCLIFSCLTWLKVWKKMAESKPETNSTLEISFGMDQETRRASDGLEEPLRMNG
GQSSSLPDAANQAEPASHEDPKCVHRKRNSLSSSHQKPPRNPVSSSDTRPSPEHQTNGTG
AQGPEAPGTNSLPSPARPHSQKAASRSRENARQAHIKRRMMTDFIVGSFDDNSSDEEPGA
GLFRESARKSSRGSLGNLSTEPALIAGDSDIHNPTIRPSMSGLHLVKRGRELKKLDLHRD
FTVASPAEFITRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERTIRFVVMVTP
EDLKANAEYIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLP
ELLCKHGIAFLGPPSEAMWALGDKIASTIVAQTLDIPTLPWSGSGLTVEWAEENLQNGKQ
ISVPEDVYGQGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPMLFRQVQ
SEVPGSPVFLMKLAQHARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAKP
DVFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMIADVNLP
AAQLQIAMGVPLHRLKDIRLLYGESPWGVTPICFETPSNPLLARGHVIAARITSENPDEG
FKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVAL
KELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDHLIAQKVQAEKPDIMLGVVCGALN
VADVVFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGVKYILKVARQSLTMFTLIMN
GSYIEIDVHQLNDGGLLLLYSGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSSS
AGKLIQYTVEDGGHVEAGDSYAEIEVMKMIMTLNVQESGVVKYIKRPGATLEAGCVVARL
ELDDPSKVHSAEPFLGTLPAQQTLPILGEKLHQVFHSVLDNLTNVMKGYCLPEPFFSTKL
KEWVQKLMTTLRDPSLPLLELQEIMTSVAGRIPVPVEKAVRRVMAQYASNITSVLCQFPS
QQIASILDCHAATLQRKDDREVFFMNTQSIVQLVQRYRSGTRGYLKTVVLDLLRSYLQVE
HHFQQAHFDKCVINLREEFKPDMSRVLDCIFSHAQVAKKNQLMIMLIDELCGPDPSLSEE
LTSILNALTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPE
NLKKLILSETTIFDVLPTFFYHANKIVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVV
EFQFMLPYSHPNRMTVPISVSNPDLLRHSTELFMDSAFTPLCQRMGAMVAFRRFEDFTRN
FDEVISCFANVPKDIPVFSKVRTTLYSEDDYKSLREEPIHILNVAIQCADHLEDEALVPI
FRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDKFAEDRIYRHLEPALAFQLE
LSRMRNFDLTAVPCANHKMHLYLGAAKVNEGVEVTDHRFFIRAIIRHSDLITREASFEYL
QNEGERLLLEAMDELEVAFNNTTVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSR
LWKLRVLQAEVKINIRPAATDSAVPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHSFG
DKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPDKYPKD
ILTYTELVLDSQDQLVEMNRLPGSNEVGMVAFKMMFKTPEYPEGREVIVISNDITHHLGS
FGLQEDMVYLRASELARAQGIPKIYLAANSGARIGLAEEIKPMFQVAWVDPENPHKGFKY
LYLKPQDYTRISALNSVHCKHIEEGGESRYVIIDIIGKEDGLGVENIKGAGMIARESSLA
YDEIITISMVTCRSLGIGAYVVRLGQRVIQVENSHIILTGVRALNKLLGREVYTSNNQLG
GVQIMHYNGVTHVTVPDDFEGVYTILEWLSYMPKDVHSPLPIITPTDPIDREVEFSPSRA
PYDPRWMLAGRPHPTLKGTWQSGFFDQGSFKEIMAPWAPTVVVGRARLGGIPVGVITAET
RTVEVMIPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIEDFNREKLPLMIFANWRGFS
GGMKDMYDQVMKFGSYIVDGLRKYKQPILIYLPPYAELRGGSWVVLDTTINPLCIEIYAD
KESRGSVLEPEGTVEIKFRKKELVKAMRRIDPTAKKLVEQLGMSELQDKDRKALEGQLKA
REELLLPVYHQVAVQFADLHDTPGRMLEKGIICDILEWRTARTFLYWRLRRLLLEAEVKQ
EILRASGELSQEHLQSMLRRWFVETEGAVKAYLWDNNQAVVQWLEQQWQGGDSQHSAIWE
NIKYLKRDAVLKTFRSLVQENPEVAMDCTVYLSQLIGPAERAQVLQLLSTMDNPAST
NT seq
7374 nt
NT seq
+upstream
nt +downstream
nt
atggtctttcttctttttctatcttgcctgattttctcctgcctgacctggctaaaagtt
tggaagaaaatggcagagtccaagccagagaccaacagtaccttggaaataagctttggc
atggaccaggagacccgtcgagcctcggatggtttagaagagccattgcgaatgaatggc
ggccagagcagctctcttccagatgctgctaaccaggcagagccagcctcccatgaagac
cccaaatgtgtccacaggaagagaaattccctgtcatcgtcacaccagaagcccccaaga
aaccctgtttcttccagtgacacacggccttccccagaacatcaaaccaatgggacaggt
gcccaaggcccagaggccccaggcaccaacagcctgccctccccagccaggccccacagc
cagaaagccgcatcccggtccagagaaaatgcgaggcaggcacacatcaagaggcggatg
atgaccgacttcatcgtgggctcctttgacgacaactcctctgacgaagagcctggtgct
ggcttgtttcgtgaatctgcccgcaaaagcagccggggcagcttgggcaacctgtccaca
gagccagctctgattgcaggggattctgacatccataacccaaccataagaccaagcatg
tctgggctccacctggtgaagaggggccgggaactcaagaagctggacctgcacagagac
ttcaccgtggcttccccagctgagttcatcacacgctttggtggggatcgggtcatcgag
aaggtgctcattgccaacaacgggatcgccgccgtgaagtgcatgcgctccatccgcagg
tgggcctatgagatgttccgcaatgagcgcaccatccggttcgtagtcatggtgacccct
gaggacctcaaggccaacgcagaatacattaagatggcagatcagtatgtccccgtccca
ggagggcccaacaacaacaactacgccaacgtggagctgattgtggacatcgccaagaga
atccccgtgcaggcagtatgggctggctggggccatgcctccgagaaccccaagcttcca
gagctgctgtgcaagcatgggattgctttcttaggaccccccagtgaggccatgtgggcc
ttgggagataagatcgcctccaccatcgtggctcagaccctcgacattcccaccctgccc
tggagtggaagcggtctgacggtggagtgggccgaggagaatctgcagaacgggaaacaa
atcagtgtcccagaagatgtttatggccagggttgtgtgaaagatgttgatgagggcttg
gaggcagcagaaaaaattggtttcccactgatgatcaaagcttctgagggaggcggaggg
aaaggaatccggaaggctgagagtgccgaagacttccccatgcttttccgacaagtgcag
agcgaggttccaggctcgcctgtttttctcatgaagctggcccagcatgcccggcacctg
gaggtccaggtcctggctgaccagtacggcaatgctgtgtcactgttcgggcgggactgc
tccatccagcggcggcatcagaagatcatcgaggaggcgccagccaccatcgccaaacca
gatgtgtttgagttcatggaacagtgtgctgtccgcttggccaagacggtgggctatgtg
agcgcagggacagttgagtatctctacagccaggatggcagcttctacttcctggagctg
aatccccgcctgcaggtggagcacccctgcacagaaatgatcgctgacgtcaacctgcca
gctgcccagctccagattgccatgggtgtgccactacaccggctgaaggacatccggctt
ctgtacggagagtctccatggggagtgacacccatttgttttgaaaccccttcaaacccc
ctcctcgcccgtggccacgtcattgcagccagaatcactagtgaaaatccagatgagggg
tttaagccaagctccgggaccgtccaggaactgaatttccgcagtagcaagaacgtgtgg
ggttacttcagcgtggccgccacaggcggcttacacgagttcgcggattcccagtttgga
cactgcttctcctggggcgagaaccgggaggaggccatttcgaacatggtggtggctttg
aaggaattgtccatccggggcgatttccggaccactgtggaatatcttattaacctcctg
gagaccgagagcttccagaacaatgacattgacactggctggttggaccatctcattgcc
cagaaagtgcaggcagagaagccggacatcatgctcggggtggtgtgcggggccctgaac
gtggcagatgtggtgttcagaacgtgcatgacggatttcttgcactctctggaaaggggc
caggtcctcccagcggattctctgctgaacattgtggatgtggaattgatttatggaggt
gtcaagtacattctcaaggtggcccggcagtctctgaccatgttcaccctcatcatgaac
ggcagctacattgagatcgacgtccaccagctgaacgatggggggttgctgctgttgtac
agtggcagcagctacaccacgtacatgaaggaagaggtggacagttatcgaatcaccatt
ggcaacaagacgtgcgtgtttgagaaggagaatgatcctacggtcctgaggtcctcgtcg
gctggcaagctgattcagtacacagtggaggatgggggccatgttgaagcaggagacagc
tacgctgagatagaggtgatgaagatgatcatgaccctgaacgtgcaggagagtggcgtg
gtgaagtacatcaagcgcccgggagccacgctggaagccggctgcgtggtggctcggctg
gagctcgatgacccttctaaagtgcactcggccgagcccttcttgggcacactccctgct
cagcagaccctacccatccttggagagaagctgcaccaggtcttccacagtgtcctggac
aacctgaccaatgtcatgaagggctactgcctgccggagcctttctttagcacaaagctg
aaagagtgggtacagaagctcatgacgacgctccgagacccatcactgccactgctggag
ctgcaggagatcatgaccagcgtggcaggacgcatccctgtccctgtggagaaggcagtc
cgcagggtcatggcccagtatgccagcaacatcacctcggtcctctgccagttccccagc
cagcagatagccagtatcctggactgtcatgcagccactctgcagcgcaaggatgaccgc
gaggtcttcttcatgaatacccagagcattgttcagttggttcagaggtaccgcagcgga
actcgaggctatttgaaaaccgtggtgctggatctcctgcgaagttatttgcaggttgaa
caccatttccaacaagcgcactttgacaaatgtgtgataaacctcagggaggagttcaag
cccgacatgtcccgcgtcctggactgcatcttctcgcatgcacaggtggccaagaagaac
cagctcatgatcatgctgattgatgagctctgtggcccggatccttccctatcagaggag
ctgacctccatcctcaatgcactcactcagctgagcaagagcgaacactgcaaagtggct
ctcagagccagacaggtgctgatcgcctcccacctcccttcctatgagctgaggcacaac
caggtggagtccatcttcctgtctgccattgacatgtacggccaccagttctgtccagaa
aacctcaagaaattaatactttcggaaaccaccatatttgatgtgcttcccactttcttc
taccatgcaaacaagatcgtctgcatggcatcactggaggtttatgtgcggaggggctac
atcgcctatgagctaaacagcctgcagcaccgagagctcccagatggcacctgtgtagtg
gaattccagttcatgctgccctattcccatccaaatcggatgacagtgcccatcagtgtc
tccaaccctgacctgctgcggcacagtacggaactcttcatggacagcgccttcacccca
ctgtgccagcggatgggggccatggtggccttcaggagatttgaggatttcaccagaaac
tttgatgaagtcatctcctgcttcgccaacgtgcccaaagacatcccagtcttcagcaag
gtccggacgacgctatactctgaggacgactacaagagcctccgagaagagcccatccac
atcctgaatgtggccatccagtgtgcagaccacctggaggacgaggcactagtgccaatt
ttccggacgtttgtacaatccaagaaaaacatccttgtggattatggactccgaagaatc
acattcttgattgcccaagagaaagagtttcccaagtttttcacattcagagcaagagat
aagtttgcagaggatcgcatttaccgtcacttggagcccgccctggccttccagctggag
ctcagccggatgcgcaactttgacctgactgctgtgccctgtgccaaccacaagatgcac
ctttacctgggtgctgccaaggtgaacgaaggggtggaagtgacggaccacaggttcttc
atccgagccatcatcaggcactcagacctgattacgagggaagcctccttcgagtacctg
cagaacgagggtgagcggctgctcctggaggccatggacgagctggaggtggcattcaac
aacacaaccgtgcgcacagactgcaaccacatcttcctcaacttcgtgcccaccgtcatc
atggacccctccaagatcgaggagtctgtgcgctccatggtcatgcgctacggtagccgg
ttgtggaaactccgcgtgctgcaggccgaggtcaagatcaatatacggccggccgccacc
gacagtgctgtacccatccgcctgtttatcacgaatgaatcgggctactacctggatatc
agcctctacaaagaagtgactgaccccagatctggaaacatcatgtttcactcctttggt
gacaagcaaggaagcctgcacgggatgctgatcaacacaccctatgtcaccaaggatctg
cttcaggctaagcgatttcaggcgcagtccctgggcaccacctacgtgtacgacttcccg
gaaatgttccggcaggctctctttaaactgtggggctccccggacaagtacccgaaagac
atcctgacgtacactgagttggtgctggactcccaggaccagctggtggagatgaaccgg
cttcctggcagcaatgaggtgggcatggtggccttcaaaatgatgttcaagaccccagag
tatccagaagggcgggaagtgatcgtcatcagcaacgacatcacccaccacttgggatcc
tttggcctacaggaggacatggtgtacctgcgggcgtcagagctggcccgggcacagggc
atccccaaaatctacctggcagccaacagtggggcccggattggcctagcagaggaaatc
aaacccatgttccaggtggcctgggtggacccagagaacccacacaaaggatttaaatac
ctgtatctgaagccccaagactacaccagaatcagcgccctgaactctgtccactgcaaa
cacattgaagaaggaggagaatccaggtacgtcatcatagacatcatcgggaaagaagac
ggcctgggtgtggagaacatcaagggcgcaggcatgattgcccgggagtcctcgctggct
tacgatgagataatcaccatcagcatggtgacctgccgctcccttgggattggggcctac
gtggtgaggctgggccagcgggtgatccaggtggaaaactcgcacatcatcctcaccgga
gtacgtgctctgaacaagctcctgggaagagaggtctacacgtccaacaaccagctgggc
ggcgtacagatcatgcactacaatggcgtcacccatgtcactgttccggacgacttcgag
ggagtgtacaccatcctggagtggctgtcctatatgccgaaggatgttcacagcccgctc
cctatcatcacacccactgatcccattgacagagaagttgagttttccccatccagagct
ccctatgaccctcggtggatgcttgctggaagacctcacccaactctgaaggggacctgg
cagagtggattcttcgaccagggcagtttcaaggaaatcatggcgccctgggccccgacc
gtggtggtaggacgagccaggctggggggtatccccgtgggtgtgattaccgcagaaact
cggaccgtggaggtaatgatccctgctgatcctgccaacctggattctgaagccaagata
atccagcaggcaggccaagtgtggttccctgactcggcttacaagacagcccaggccatc
gaggacttcaaccgggagaagctgcccctgatgatctttgccaactggaggggtttctct
gggggcatgaaagacatgtatgaccaggtgatgaaatttggatcctacattgtggacggc
ctccggaagtacaaacagcccatcctgatctacctcccaccctacgctgagctccgaggg
ggctcttgggtggtcctggacaccaccatcaacccgctgtgcatagagatatatgcagac
aaagagagtaggggcagcgtgctggagccggagggaactgtggagattaagttccgaaag
aaggagctggtaaaggccatgagaaggatcgacccgaccgccaagaagctggtggagcag
ctcgggatgtcggagctgcaggacaaagatcgcaaggccctggagggccagctgaaggct
cgcgaggagctgctcctccccgtctaccaccaggtggcggtgcagtttgcggacctgcac
gacacgccaggccggatgctggagaagggcatcatctgcgacatactggagtggaggacg
gcgcgcaccttcctatactggcgtctgcgccgcctcctcctggaggctgaggtcaagcag
gagatcctccgggccagcggtgaactgagccaggagcacctgcagtccatgctgcgccgc
tggttcgtggagaccgagggagccgtcaaggcctacctgtgggacaataaccaggcggtg
gtgcagtggctggagcagcaatggcaggggggcgatagccagcactcggccatttgggag
aacatcaagtacttgaagcgtgatgctgtcctcaagaccttccgcagtctggtccaggaa
aacccagaggtggccatggactgcacggtatacctgagccagctcatcggcccagctgag
cgggcccaggtgctccaactgttgtccacgatggacaacccggcctccacctga
DBGET
integrated database retrieval system
