KEGG   Cavia porcellus (domestic guinea pig): 100729225
Entry
100729225         CDS       T07777                                 
Symbol
Dhfr
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc00670  One carbon pool by folate
cpoc00790  Folate biosynthesis
cpoc01100  Metabolic pathways
cpoc01240  Biosynthesis of cofactors
cpoc01523  Antifolate resistance
cpoc04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100729225 (Dhfr)
   00670 One carbon pool by folate
    100729225 (Dhfr)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100729225 (Dhfr)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100729225 (Dhfr)
Enzymes [BR:cpoc01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     100729225 (Dhfr)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 100729225
NCBI-ProteinID: XP_003479566
Ensembl: ENSCPOG00000020993
UniProt: H0VYF1
LinkDB
Position
Unknown
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFGYFQRMTTTPSVEGKQNLVIMGRKTWFS
LPEKSRPLKDRINVVLSRELKEPPQGAHFLAPSLDDALKLIEQPGLANEVDMVWIVGGSS
VYKEAMERPGHIKLFVTRIMQEFESDTFFPEIDLKKYRLLPEYPGVPSEIQEEKGIKYKF
EVYEKND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgccctctgaactgtatcgtcgccgtgtcacagaacatgggcatcggcaagaac
ggggacttgccctggcccccgctcaggaatgaattcgggtatttccagaggatgaccacg
accccctctgtggaaggtaaacagaatctggtgatcatgggtaggaagacctggttctcc
cttcctgagaagagtcgacctttgaaagacagaattaatgtagtactaagtagagaactc
aaggaacctccccaaggagcccattttcttgcccctagtctggacgatgccttgaagctg
attgaacagccaggattagcgaatgaagtggacatggtgtggattgtggggggcagctct
gtttacaaggaagccatggaacggccaggccacatcaaactgtttgtgacaagaatcatg
caggaatttgaaagtgacacatttttcccagaaatcgatttgaagaaatacaggctcctc
ccagagtacccaggtgtgccttctgagatccaggaggagaagggcatcaagtacaaattt
gaagtctatgaaaagaacgattaa

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