Cavia porcellus (domestic guinea pig): 100732797
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Entry
100732797 CDS
T07777
Symbol
Ptpn11
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 11
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc04014
Ras signaling pathway
cpoc04072
Phospholipase D signaling pathway
cpoc04148
Efferocytosis
cpoc04360
Axon guidance
cpoc04625
C-type lectin receptor signaling pathway
cpoc04630
JAK-STAT signaling pathway
cpoc04650
Natural killer cell mediated cytotoxicity
cpoc04660
T cell receptor signaling pathway
cpoc04670
Leukocyte transendothelial migration
cpoc04722
Neurotrophin signaling pathway
cpoc04920
Adipocytokine signaling pathway
cpoc04931
Insulin resistance
cpoc05168
Herpes simplex virus 1 infection
cpoc05205
Proteoglycans in cancer
cpoc05208
Chemical carcinogenesis - reactive oxygen species
cpoc05211
Renal cell carcinoma
cpoc05220
Chronic myeloid leukemia
cpoc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100732797 (Ptpn11)
04630 JAK-STAT signaling pathway
100732797 (Ptpn11)
04072 Phospholipase D signaling pathway
100732797 (Ptpn11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100732797 (Ptpn11)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100732797 (Ptpn11)
04660 T cell receptor signaling pathway
100732797 (Ptpn11)
04670 Leukocyte transendothelial migration
100732797 (Ptpn11)
09156 Nervous system
04722 Neurotrophin signaling pathway
100732797 (Ptpn11)
09158 Development and regeneration
04360 Axon guidance
100732797 (Ptpn11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100732797 (Ptpn11)
05208 Chemical carcinogenesis - reactive oxygen species
100732797 (Ptpn11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100732797 (Ptpn11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100732797 (Ptpn11)
05211 Renal cell carcinoma
100732797 (Ptpn11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100732797 (Ptpn11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
cpoc01009
]
100732797 (Ptpn11)
Enzymes [BR:
cpoc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
100732797 (Ptpn11)
Protein phosphatases and associated proteins [BR:
cpoc01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
100732797 (Ptpn11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
100732797
NCBI-ProteinID:
XP_013000285
Ensembl:
ENSCPOG00000013527
LinkDB
All DBs
Position
Unknown
AA seq
593 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPSDPXGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLADQTGGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaacatcaccggcgtggaggcagaaaatctactg
ttgaccagaggagtcgatggcagttttttggcgaggcccagtaaaagtaaccctggagac
ttcaccctttcagttaggagaaatggagctgtcacccacatcaagattcagaacacaggt
gactactatgacctgtatggaggagagaagtttgccactttggctgagctggtccagtat
tacatggaacatcatgggcagctgaaagagaagaatggagacgttatcgagctcaaatat
ccactgaactgtgcagatcctacctctgaaaggtggtttcatggtcatctttctgggaaa
gaagcagagaaattactaactgagaagggaaaacatggtagctttcttgtccgagagagc
cagagccaccctggagattttgttctctctgtccgcactggtgatgacaaaggggagagc
aatgacggcaaatcgaaggtgacacacgtcatgatccgctgccaggaactgaagtatgat
gttggtggaggagaacggtttgattccttgacagatctggtggagcattacaagaagaat
cccatggtagagacattgggcacagtgctccaactgaagcagcccctcaacaccacccgt
atcaacgcggccgagattgaaagccgggttcgagagttgagcaaactggccgagaccacg
gataaggtcaagcaaggcttctgggaagaattcgagacgctacagcaacaggagtgcaaa
cttctgtacagccgaaaagagggccagaggcaagaaaataaaaacaaaaataggtacaaa
aacatcctgccctttgatcacaccagggtcgtcctccacgatggtgaccccaatgagcct
gtgtctgactacatcaacgccaacatcatcatgcctgaatttgaaaccaagtgcaacaat
tcaaagcccaaaaagagctacattgccacacaaggctgcctgcagaacacggtgaacgac
ttttggcgaatggtgttccaggagaactctcgagtgattgtcatgacgacgaaagaagtg
gagcgagggaagagcaaatgtgtcaagtactggccggacgagtatgccctcaaagagtat
ggggtcatgcgtgtcaggaatgtcaaagagagtgctgctcatgactacacactaagagaa
cttaaactctccaaggttggacaagggaatacggagagaacggtctggcaataccacttt
cggacctggccggaccacggtgtgcccagtgaccccnggggtgtgctggacttcctggag
gaggtccaccacaagcaggagagcatcgtggatgcaggccccgtcgtggtgcactgcagt
gctggaattggccggacagggacattcatcgtgatcgatatccttattgacatcatcaga
gagaaaggtgttgactgtgacatcgacgttcccaaaaccattcagatggtgcggtctcag
aggtcagggatggtccagaccgaagcccagtaccggtttatctacatggctgtccagcat
tacatcgaaacactacagcgcaggatcgaggaagagcagaaaagcaagaggaaagggcac
gaatacaccaacattaagtattccctagcggaccagacaggtggcgatcagagtcctctc
ccgccgtgcacacccacgccaccctgtgcggaaatgagagaagacagtgccagagtctac
gagaacgtgggcttgatgcagcagcagaagagcttcagatga
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