Chlorocebus sabaeus (green monkey): 103217981 Help Entry 103217981         CDS       T04361                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism csab  Chlorocebus sabaeus (green monkey) Pathway csab04022   cGMP-PKG signaling pathway csab04068   FoxO signaling pathway csab04081   Hormone signaling csab04140   Autophagy - animal csab04150   mTOR signaling pathway csab04151   PI3K-Akt signaling pathway csab04152   AMPK signaling pathway csab04211   Longevity regulating pathway csab04213   Longevity regulating pathway - multiple species csab04722   Neurotrophin signaling pathway csab04910   Insulin signaling pathway csab04920   Adipocytokine signaling pathway csab04923   Regulation of lipolysis in adipocytes csab04930   Type II diabetes mellitus csab04931   Insulin resistance csab04932   Non-alcoholic fatty liver disease csab04935   Growth hormone synthesis, secretion and action csab04960   Aldosterone-regulated sodium reabsorption csab05010   Alzheimer disease csab05206   MicroRNAs in cancer csab05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:csab00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     103217981 (IRS1)    04022 cGMP-PKG signaling pathway     103217981 (IRS1)    04151 PI3K-Akt signaling pathway     103217981 (IRS1)    04152 AMPK signaling pathway     103217981 (IRS1)    04150 mTOR signaling pathway     103217981 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     103217981 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103217981 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103217981 (IRS1)    04923 Regulation of lipolysis in adipocytes     103217981 (IRS1)    04920 Adipocytokine signaling pathway     103217981 (IRS1)    04935 Growth hormone synthesis, secretion and action     103217981 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     103217981 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     103217981 (IRS1)   09149 Aging    04211 Longevity regulating pathway     103217981 (IRS1)    04213 Longevity regulating pathway - multiple species     103217981 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     103217981 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     103217981 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     103217981 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103217981 (IRS1)    04932 Non-alcoholic fatty liver disease     103217981 (IRS1)    04931 Insulin resistance     103217981 (IRS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  103217981 NCBI-ProteinID:  XP_007964663 LinkDB All DBs Position 10:complement(112748283..112812368) Genome browser AA seq 1250 aa AA seqDB search MASPPESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPN GHYILSRGGNGHRYTPGTGLGTSPALAGDEASSAADLDNRFRKRTHSAGTSPTITHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTHSYPEEGLEMHPLERRGGHHR PDSSTLHTDDGYMPMSPGVAPVPSSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGGCSPDIGGGPSSSSSSTVPSGSSYGKLWTNGVGGHHSQVLPHPKPPVESSG GKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEE GARHQHLHLSASSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLP RKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQHQQQQQQQQQQQQQPLLHPPEPKS PGEYVNIEFGSDQPGYLSGPVASRSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRA AWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPIAPVSY ADMRTGIAAEEVSLPRATMAAAASSSAASASPTGPQGAAELAAHSSLLGGAQGPGGMSAF TRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAIGGSGGSS SSSEDVKRHSSASFENVWLRPGELGGAPKEPAQLCGAAGGLENGLNYIDLDLVKDFKQRP QECTPQPQPPPPPPPHQPLGSSESSSTRRSSEDLSAYASISFQKQPEDLQ NT seq 3753 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctccggagagcgatggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagcatgcacaaacgcttcttcgtactgcgcgcggccagcgaggctgggggc ccggcgcggctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatcccccttgagagctgcttcaacatcaacaagcgggctgactccaagaac aagcacctggtggctctctacacccgggacgagcactttgccatcgcggcggacagcgag gcggagcaagacagctggtaccaggctctcctacagctgcacaaccgtgccaagggccac cacgacggagctgcggccctcggggcgggaggtggcgggggcagctgcagcggcagctcc ggccttggtgaggctggggaggacttgagctacggtgacgtgcccccaggacccgcgttc aaagaggtctggcaggtgatcctgaagcccaagggcctgggtcagacaaagaacctgatt ggtatctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaactcggag gcagccgccgtggtgctgcagctgatgaacatcaggcgctgcggccactcggagaacttc ttcttcatcgaggtgggccgttctgccgtgacggggcccggggagttctggatgcaggtg gatgactccgtggtggcccagaacatgcatgagaccatcctggaggccatgcgggctatg agcgatgagtttcgccctcgcagcaagagccagtcctcgtccaactgctccaaccccatc agcgtccccctgcgccggcaccatctcaacaaccccccgcccagtcaggtggggctgacc cgccgatctcgcactgagagcatcaccgccacctccccggccagcatggtgggcgggaag ccaggctccttccgcgtccgcgcctccagtgacggcgaaggcaccatgtcccgcccagcc tcggtggatggcagccctgtgagtccgagcaccaacagaacccacgcccaccggcatcgg ggcagcgcccggctgcatcccccgctcaaccacagccgctccatccccatgccagcttcc cgctgctcgccttcggccaccagccccgtcagtctgtcgtccagcagcaccagcggccat ggctccacctcggattgtctcttcccacggcgctctagtgcttcggtgtctggttctccc agcgatggcggtttcatctcctcagatgagtatggctccagtccctgcgatttccggagt tccttccgcagtgtcactccggattccctgggccacaccccaccagcccgcggtgaggag gagctaagcaactatatctgcatgggcggcaaggggccctccaccctgaccgcccccaac ggtcactacattttgtctcggggtggcaatggccaccgctacaccccaggaacaggcttg ggcacgagtccagccttggctggggatgaagcatccagtgctgcggatctggataatcgc ttccgaaagagaactcactctgcaggcacatcccctaccattacccaccagaagaccccg tcccagtcctcagtggcttccattgaggagtacacagagatgatgcctgcctacccacca ggaggtggcagtggaggccgactgccgggacacaggcactctgccttcgtgcccacccac tcctacccagaggagggtctggaaatgcaccccttggagcgtcgggggggccaccaccgc ccagacagctctaccctccacactgatgatggctacatgcccatgtccccaggggtggcc ccagtgcccagcagccgaaagggcagtggagactatatgcccatgagccccaagagcgtg tctgccccacagcagatcatcaatcccatcagacgccatccccagagagtggaccccaat ggctacatgatgatgtcccccagcggtggctgctctcctgacattggaggtggccccagc agcagcagcagcagcaccgtcccttccgggagcagctatggaaagctgtggacaaacggg gtagggggccaccactctcaggtcttgcctcaccccaaacccccagtggagagcagcggt ggcaagctcttaccttgcacaggtgactacatgaacatgtcaccagtgggggactccaac accagcagcccctccgactgctactatggccctgaggacccccagcacaagccagtcctc tcgtactactcattgccaagatcctttaagcacacccagcgccccggggagccggaggag ggtgcccggcatcagcacctccacctttccgctagctctggtcgccttctctatgctgca acagcggatgattcttcctcctccaccagcagcgacagcctgggtgggggatactgtggg gctaggctggagcccagccttccacatccccaccatcaggttctgcagccccatctgcct cgaaaggtggacacagctgctcagaccaatagccgcctggcccggcctacgaggctgtcc ctgggggatcccaaggccagcaccttacctcgggcccgagagcagcagcatcagcagcag cagcagcaacagcagcaacagcaacagcagcccctgctgcaccctccggagcccaagagc ccaggggaatatgtgaatattgaatttgggagtgatcagcctggctacttgtctggccca gtggcttcccgtagctcaccttctgtcaggtgtccatcccagctccagccagctcccaga gaggaggagactggcactgaggagtacatgaagatggacctggggccgggccggagggca gcctggcaggagagcactggggtcgagatgggcagactgggccccgcacctcccggggct gctagcatttgcaggcctacccgggcagtgcccagcagccggggtgactatatgaccatg cagatgagttgtccccgccagagctatgtggacacttcgccaattgcccctgtaagctat gctgacatgcggacaggcattgctgcagaggaggtgagcctgcccagggccaccatggct gctgccgcctcatcctcagcagcctctgcttcccccactgggcctcaaggggcagcagag ctggctgcccactcatccctgctggggggcgcacaaggacctgggggcatgagtgccttc acccgggtgaacctcagtcctaaccgcaaccagagtgccaaagtgatccgtgcagaccca caagggtgccggaggaggcatagctccgagaccttctcctcaacacccagtgccacccgg gtgggcaacacagtgccctttggagccggggcagcaatagggggcagtggcggtagcagc agcagcagcgaggatgtgaaacgccacagctctgcttcctttgagaatgtgtggctgagg cctggggaacttgggggagcccccaaggagccagcccaactgtgtggggctgctgggggt ttggagaatggtcttaactacatagatctggatttggtcaaggacttcaaacagcgccct caggagtgcacccctcagccgcagcctcctccacccccaccccctcatcaacccctgggt agcagtgagagcagctctacccgccgctcaagtgaggatttaagcgcctatgccagcatc agtttccagaagcagccagaggaccttcagtag

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