Chlorocebus sabaeus (green monkey): 103230154
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Entry
103230154 CDS
T04361
Symbol
HSD11B1
Name
(RefSeq) hydroxysteroid 11-beta dehydrogenase 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
csab
Chlorocebus sabaeus (green monkey)
Pathway
csab00140
Steroid hormone biosynthesis
csab00980
Metabolism of xenobiotics by cytochrome P450
csab01100
Metabolic pathways
csab05204
Chemical carcinogenesis - DNA adducts
Module
csab_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
csab00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
103230154 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
103230154 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
103230154 (HSD11B1)
Enzymes [BR:
csab01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
103230154 (HSD11B1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
2-Hacid_dh_C
Pyr_redox_3
Pyr_redox_2
Shikimate_DH
NAD_binding_2
AdoHcyase_NAD
Motif
Other DBs
NCBI-GeneID:
103230154
NCBI-ProteinID:
XP_007986782
Ensembl:
ENSCSAG00000015252
UniProt:
A0A0D9RRW1
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All DBs
Position
25:complement(19720096..19772806)
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AA seq
292 aa
AA seq
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MAFMKKYLLPILGLFMAYYYYSAYEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMV
AAYSASKFALDGFFSSIRKEYSLAKVNVSITLCVLGLIDTDTAMKAVSGIINMQAAPKEE
CALEIIKGGALRQEEVYYDSSLWTTLLLRNPCRKILEFLYSSTYNMDRFTKN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatatctcctccccattctggggctcttcatggcctactactac
tattctgcatatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaagggatcggaagagagatggcttatcatctggcgaagatgggagcccac
gtggtggtaacagcgaggtcaaaagaaactctacagaaggtggtttcccactgcctggaa
cttggagcagcctcagcacactacattgctggcaccatggaagacatgaccttcgcagag
caatttgttgcccaagcaggaaagctcatgggaggactagacatgctcattctcaaccac
atcaccaacacttctttgaatctttttcatgatgatattcaccatgtgcgcaaaagcatg
gaggtcaacttcctcagttatgtggtcctgactgtagctgccttgcccatgctgaagcag
agcaatggaagcattgttgtcgtctcttctttggctgggaaagtggcttatccaatggtt
gctgcctattctgcaagcaagtttgctttggatgggttcttctcctccatcagaaaggaa
tattcattggccaaggtcaatgtatcaatcactctctgtgttcttggcctcatagacaca
gacacagccatgaaggcagtttctgggataatcaatatgcaagcagctccaaaggaggaa
tgtgcccttgagatcatcaaagggggagctctgcgccaagaagaagtatattatgacagc
tcactctggaccactcttctgttgagaaatccatgcaggaagatcctggaatttctttac
tcatcgacctataatatggacagattcacaaaaaactag
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