KEGG   Clostridium scindens: HDCHBGLK_01250
Entry
HDCHBGLK_01250    CDS       T06591                                 
Symbol
folA
Name
(GenBank) Dihydrofolate reductase
  KO
K18590  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
csci  Clostridium scindens
Pathway
csci00670  One carbon pool by folate
csci00790  Folate biosynthesis
csci01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:csci00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    HDCHBGLK_01250 (folA)
   00670 One carbon pool by folate
    HDCHBGLK_01250 (folA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:csci01504]
    HDCHBGLK_01250 (folA)
Enzymes [BR:csci01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     HDCHBGLK_01250 (folA)
Antimicrobial resistance genes [BR:csci01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    HDCHBGLK_01250 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: QBF73861
UniProt: A0A494WNX2
LinkDB
Position
1216581..1217099
AA seq 172 aa
MIGLIVARSKNNVIGKNGKIPWKIKGEQKQFRELTTNKTVIMGRKSYNEIGHPLANRLNI
IVSNTANYTGENLITVHSLNEAIQVAGNKDIFVIGGYSLYKEALPIVDKMYITEIDIEVS
NGDVFFPQFNIDNFELSIGETFGNDIKYTRTLYTRKRWIPNCVAKNMLESSG
NT seq 519 nt   +upstreamnt  +downstreamnt
atgataggattgatagtagcacgctccaaaaataatgtcatagggaaaaatgggaaaata
ccatggaaaatcaagggagagcagaaacaattcagagagttgacaacaaataaaactgtt
attatgggacgaaaatcttacaatgaaattggacatccacttgcaaacagattaaatatt
atagtatctaatacagcaaattatacaggagaaaacttgataacagttcattctctcaat
gaagcaattcaagtcgctggaaataaagatatctttgtgatcggcggatatagtttatat
aaagaagcgttgccaattgtagataaaatgtatattacagaaattgatatagaggtgtca
aatggggatgtctttttcccacaattcaatatagataattttgaattgtctattggagaa
acatttggaaatgatattaaatatactcgcacgctttatactagaaaaagatggattcca
aattgcgtggcaaagaatatgcttgaatcatctggataa

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