Citrobacter sedlakii: JY391_21370
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Entry
JY391_21370 CDS
T07832
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
csed
Citrobacter sedlakii
Pathway
csed00260
Glycine, serine and threonine metabolism
csed00261
Monobactam biosynthesis
csed00270
Cysteine and methionine metabolism
csed00300
Lysine biosynthesis
csed01100
Metabolic pathways
csed01110
Biosynthesis of secondary metabolites
csed01120
Microbial metabolism in diverse environments
csed01230
Biosynthesis of amino acids
Module
csed_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
csed_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
csed_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
csed00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
JY391_21370 (metL)
00270 Cysteine and methionine metabolism
JY391_21370 (metL)
00300 Lysine biosynthesis
JY391_21370 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
JY391_21370 (metL)
Enzymes [BR:
csed01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
JY391_21370 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
JY391_21370 (metL)
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Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
HTH_11
Motif
Other DBs
NCBI-ProteinID:
QUC29996
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All DBs
Position
complement(4520974..4523406)
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AA seq
810 aa
AA seq
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MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDMMVVSAAGSTTNQLISW
LKLSQTDRLSAHQVQQTLRRYQCDLISGLLPADVADSLISLFISDLERLAALLDSGVTDA
VYAEVVGHGEVWSARLMSAVLNQQGMESAWLDAREFLRAERAAQPQVDEGLSYPLLQQLL
VQHPGKRLVVTGFISRSNAGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSDIDLQLRCSYTPDQGSTRIER
VLASGTGARIVTSHDDVCLIEFQVPASQDFKLAYKDIDQILKRAQVRPLAVGVHHDRQLL
QFCYTSEVADSALRILDEAGLPGELRLRQGLALVAMVGAGVTRNPLHCHRFWQQLKGQPV
EFTWQSEEGISLVAVLRTGPTESLIQGLHQSLFRAEKRIGLVLFGKGNIGSRWLELFARE
QSTLSARTGFEFVLAGVVDSRRSLLNYEGLDASRALAFFGDEAVEQDEESLFLWMRAHPY
DDLVVLDVTASEQLADQYLDFASHGFHVISANKLAGASNSDKYRQIHDAFDKTGRHWLYN
ATVGAGLPINHTVRDLIDSGDTILSISGIFSGTLSWLFLQFDGTVPFTELVDQAWQQGLT
EPDPRVDLSGKDVMRKLVILAREAGYDIEPDQVRVESLVPAHCEEGSIDHFFENGDELNE
QMVQRLEAAREMGLVLRYVARFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq
2433 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtgattgcgcaggcaggggcgaagggtcgccaactgcataaatttggtggcagt
agtctggctgacgtgaagtgttatctgcgcgtggcgggcattatggcggaatactcacag
cctgacgatatgatggtggtttccgccgcaggcagcaccaccaaccagttgattagctgg
ctgaaactcagtcagaccgatcgcctctctgcgcatcaggtgcaacaaacccttcgtcgc
tatcagtgcgatctgatcagcggtctgctgcctgccgatgtggcggacagtttgatcagt
ctgttcatcagcgacctggaacgtctggcggcgctgctggacagcggcgtcaccgatgcg
gtctacgcggaagtggtcggccacggcgaagtctggtccgcgcggctgatgtccgcggtg
ctcaatcagcagggaatggaatccgcctggctggatgcgcgcgaatttctccgcgccgag
cgcgccgcgcagccgcaggtcgacgaaggtttatcttatccgttgttgcaacagttgctg
gtgcagcatccgggcaaacgtctggtggtcacgggttttatcagccgcagcaatgcgggt
gaaacggtactgctggggcgcaacggttctgactactcggcgacgcagataggcgcgctg
gcgggcgtttcccgggtcaccatctggagcgacgtcgccggggtttacagcgccgatccg
cgcaaggtgaaagatgcctgcctgctgcccctgttgcgtctggatgaagccagcgagctg
gcgcgtctggccgcgccggtgctgcatgcgcgcacgctgcagcccgtttccggcagcgat
atcgatctgcaattacgctgtagctacacgccggatcaggggtccacgcgcattgaacgt
gtgctggcctccgggacaggcgcgcgtatcgttaccagtcatgatgatgtgtgcctgatt
gagtttcaggtgcccgcgagccaggactttaagctggcgtataaggatatcgaccagatc
ctgaaacgcgcgcaggtgcgtccgctggcggtgggcgtccatcacgatcgtcaactgctt
cagttctgttacacctctgaagtcgccgacagcgcgctgaggatccttgacgaggcgggc
ttaccgggagaactgcgcctgcggcaggggcttgcgctggtggcaatggtcggcgcgggg
gtcacccgcaacccgctgcactgccaccgtttttggcagcaactaaaaggtcagccggtc
gagttcacctggcaatcggaagagggcatcagcctggtcgcggtgttacgtacaggccca
accgaaagcctgattcagggcttacatcagtctcttttccgcgccgaaaagcgtatcggt
ctggtgctgtttggtaagggcaatattggctcccgttggctggaactgtttgcccgcgag
cagagcacgttgtcggcgcgtaccgggtttgaatttgtgctggcgggcgtggtggacagt
cgccgcagcctgctgaactacgaaggactggatgccagccgtgcgctggcgttctttggc
gacgaagccgttgaacaggatgaagagtcgctgtttttatggatgcgcgcgcacccgtac
gatgatctggtggtgctggacgtgacggcgagcgagcaactggcggatcaatatctcgac
tttgccagccacggttttcacgttatcagcgccaataaactggccggggcgagcaacagt
gacaagtaccggcaaattcacgacgcgtttgataaaacgggtcgccactggctgtataac
gccaccgtgggggccggattgccgatcaaccataccgtgcgcgatctcatcgacagtggc
gataccattttgtcgatcagtgggatcttctccggtacgctctcgtggctgttcctgcag
tttgacggcaccgtgccgttcaccgaactggtggatcaggcctggcagcaggggctgacc
gagccggacccgcgtgtggatctgtccggtaaagacgtgatgcgtaagctggtgattctg
gcacgtgaagcaggttacgatatcgagccggatcaggtgcgcgtcgagtcgttggtaccc
gcgcattgcgaagagggctccatcgaccatttctttgaaaacggcgatgagctgaacgag
cagatggttcagcgtctggaggccgcccgcgagatggggctggtgctgcgctacgtggcg
cgttttgacgctaacggtaaagcgcgcgttggcgtcgaagccgtgcgcccggagcatccg
ctggcggcgctgctgccgtgtgataacgtgtttgccatcgaaagccgctggtatcgcgac
aacccgctggtgatccgcgggccgggcgcgggacgcgacgtgaccgccggggcgattcag
tcggacatcaaccgcctggcgcaactgttataa
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