Cynoglossus semilaevis (tongue sole): 103391994
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Entry
103391994 CDS
T04866
Symbol
hsd3b1
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
csem
Cynoglossus semilaevis (tongue sole)
Pathway
csem00140
Steroid hormone biosynthesis
csem01100
Metabolic pathways
Module
csem_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
csem_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
csem_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
csem00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
103391994 (hsd3b1)
Enzymes [BR:
csem01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
103391994 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
103391994 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
KR
RmlD_sub_bind
adh_short
NmrA
Motif
Other DBs
NCBI-GeneID:
103391994
NCBI-ProteinID:
XP_008326727
UniProt:
A0A3P8VJ35
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Position
16:complement(9002158..9005815)
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AA seq
373 aa
AA seq
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MSLEGDVCVVTGACGFLGKRLVKLLLEEENAAEIRMLDKHVQPQVLQELTDCRGKTKLSV
FEGDIRDGEFVRKACRAASVVFHTASIIDVNESVEYSEMYGVNVTGTQVLLEACIQENVV
AFIYTSSIEVMGPNPKGEPIINGNEDTFYNCTLKFSYSKTKKEAERRTLASHGELLRNGG
RLATCALRPMYIYGEGCRFLLGHMGDGIRNKDVLLRMSQPEARVNPVYVGNAALAHLQAA
RCLKDPQRRNLVGGKFYFAADDTPPVSYSDFNHVMMSPLGFSIQEKLMMPLRLFYVVCFF
LEVVCMLLRPFVRIVPPLNRQLLTMLNTHFTFSYQRAQQDLGYNPRYSWEEARKRTMEWL
ASQLPKERERIRG
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atgtctctggaaggtgatgtgtgcgtagtgacgggagcctgtggattcctgggaaagagg
ctggtgaagctgctgctggaggaagagaacgcggccgagattcggatgctggacaaacac
gtgcagccgcaggttctacaggagctgacggattgtagaggcaaaaccaagctgagtgtt
ttcgagggcgacattagagacggtgaatttgtgaggaaggcctgtcgcgccgcttcggtc
gtctttcacaccgcgtccatcatcgatgtgaacgagtcagtggagtacagcgagatgtat
ggagttaatgtcacagggacccaggtcctcctggaggcgtgtatccaggagaacgtggtc
gccttcatttataccagcagcatcgaagtgatggggccaaaccctaagggcgagcctatc
atcaatggcaatgaggacaccttctacaactgcaccctgaagttctcctacagcaagacc
aagaaagaggcagagcggagaaccctggcgtcccacggtgagctgctccgaaacggaggc
cgactggccacctgtgcactcaggcccatgtacatctacggagaaggatgtcgcttcctg
ctcggccacatgggtgacgggatacgaaacaaggacgtcctcctgcggatgtcccaacca
gaagctcgggtgaaccccgtctacgtcggcaacgcagcgttagctcatctccaagccgct
cgctgcctgaaggatccgcagaggaggaacttagtcggaggaaagttctacttcgcggcc
gacgacaccccgcccgtgagctactcggacttcaaccacgtcatgatgtcgcctctgggc
ttcagcatccaggagaaactcatgatgccgctccgcctcttctacgtggtgtgcttcttt
ttggaggtcgtgtgcatgctgctgcgacctttcgtacgcatcgtgccgccacttaaccgg
cagctgctcaccatgctgaatacgcacttcaccttctcctatcagagagctcagcaggat
ctggggtacaacccccggtacagctgggaggaggcgcgcaaacgcacgatggaatggctc
gcatcacaactgccgaaggagagagaacgaataagaggctaa
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