KEGG   Cytobacillus spongiae: LS684_21425
Entry
LS684_21425       CDS       T09119                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
cspg  Cytobacillus spongiae
Pathway
cspg00270  Cysteine and methionine metabolism
cspg00450  Selenocompound metabolism
cspg00670  One carbon pool by folate
cspg01100  Metabolic pathways
cspg01110  Biosynthesis of secondary metabolites
cspg01230  Biosynthesis of amino acids
cspg04980  Cobalamin transport and metabolism
cspg04981  Folate transport and metabolism
Module
cspg_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:cspg00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    LS684_21425 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    LS684_21425 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    LS684_21425 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    LS684_21425 (metH)
   04980 Cobalamin transport and metabolism
    LS684_21425 (metH)
Enzymes [BR:cspg01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     LS684_21425 (metH)
SSDB
Motif
Pfam: S-methyl_trans Met_synt_B12 Pterin_bind B12-binding B12-binding_2 CdhD CTP_transf_3 DUF5745
Other DBs
NCBI-ProteinID: UII58182
LinkDB
Position
unnamed:187720..191166
AA seq 1148 aa
MAITLFEQQLRKKILVLDGAMGTMLQQAELSPEDFGGEKLDGCNENLVLTAPEVIYRIHL
EYLDAGADVIETNTFGATPVVLDEYDLGYKAYEINKVAAEIAKKVARERSTPDWPRFVAG
SLGPTTKTLSVTGGISFGELVDNYRVQAEGLLDGGVDVLLLETSQDALNVKAANLGIRTA
FDTIGKEVPILLSGTIEPMGTTLAGQNIEAFYLSLEHLNPIVVGLNCATGPEFMRDHIRS
LSSLATTYVSCYPNAGLPDEEGNYNETPDSLSVKMKGFAEKGWLNLVGGCCGTTPDHIRA
LSESVSGLPPRKPNDSHPHAVSGIDPFLYEDEGLRPILVGERTNVIGSRKFKRLIAEGKM
EEASEIARAQVKNGAQIIDICLADPDREEDADMNVFIQEVVKKVKVPLIIDSTDENVMET
ALKHIQGKAIINSINLEDGEERFEKVTKLMKEYGAAVVVGTIDEKGMGVSVERKVEIAHR
SHKLLTEKYGISSEDIIFDPLVFPVGTGDDQYIGSAEATVEGIKKIKEVLPKCPHILGIS
NVSFGLPPVGREVLNAVYLYHCTKAGLDYAIVNTEKLERFASIPDEEVKMAEKLLFKTSD
SSLAEFTAYYRGKKKEVKVPVNTMTLEERLSHYVVEGTKQGLVDDLEIALQKYESPLDII
NGPLMEGMSEVGRLFNDNQLIVAEVLQSAEVMKASVAHLEPHMKQTASSSTKGKVILATV
KGDVHDIGKNLVDIILSNNGYEVIDLGIKVSPQQLIDVIKEEKPDIVGLSGLLVKSAQQM
VITANDLKQSDISVPLVVGGAALTRKFTTNKIGMEYDGLVLYAKDAMDGLSIMNGIQHAE
TRKRMEEESIEKRSKFVSVRESPARKQSATAVISRSSVAKDVKVHIPADLFPHTIKEFSL
DQIQPYINQQMLLGHHLGIKGKISRLLEEGDERTVGLKAVTDELFQKAKQKGMIQGSARY
QFFPAQSDGDDVIIYHPDDPSVEMERFHFPRQGGNQCLCLADYLRSVESGELDYVGFFAV
TAGVKIRQWAKELKEAGRFLESHALQALALETAEGLAERVHEMMRSRWGFPDPVDFTMQD
RFRTHYQGQRFSFGYPACPELEDQKKLFKLIQPETIGIHLTDGCMMEPEASVTAMVFAHP
EARYFNVL
NT seq 3447 nt   +upstreamnt  +downstreamnt
atggccatcacattgtttgaacaacaactcagaaaaaaaatacttgtactcgatggagca
atgggaacgatgcttcaacaagcggaattatctcctgaagactttggaggggaaaagctt
gacggttgtaatgaaaatcttgttttgacagcccctgaagtcatttataggattcatctt
gaatacctggatgcaggagcagatgtgattgaaacgaacacatttggagcaactcccgtg
gtactggatgaatatgatctgggctacaaagcttatgaaataaacaaagtggccgcagaa
atcgccaaaaaagtggcccgtgaaagatcgactccagattggccgagatttgttgcgggt
tctctcgggccaactactaaaaccctatctgtcacagggggaataagcttcggtgagtta
gtagataactaccgtgttcaagctgaaggccttcttgatggaggagtggatgtgctcctg
cttgaaacgagtcaggatgcattgaatgttaaagcggcaaatcttgggatacggacagca
tttgataccatagggaaagaagtacctattcttttatccgggacgatcgagcccatggga
accacactggcaggtcagaatatcgaagcattttatttatcattggaacatttgaatcca
atagtcgtaggattgaactgtgcgactggtcctgaatttatgagagaccatatccgttcc
ttatcaagtctcgcaactacgtatgtcagttgttaccccaatgccggtttaccggatgag
gaggggaattacaacgagacccctgactcactaagtgtgaagatgaaaggcttcgctgag
aagggctggcttaatctcgtaggaggctgctgtggaaccacccctgaccatatccgtgcc
ctttcagaatccgtgagtgggctgccgccccggaagcctaacgattcacatcctcatgcg
gtttcaggtattgacccttttctatatgaagatgagggtctaagaccaatcctggtcgga
gaaaggacaaatgtcatcggctccaggaaattcaagagattgatagctgaaggtaaaatg
gaagaagcttcagagattgcaagggcacaagtgaagaatggtgcccagatcatcgatatt
tgccttgcagacccagaccgtgaagaagatgcggatatgaatgtatttatacaggaggtg
gtcaagaaagttaaagtcccccttatcattgattctactgatgagaatgtgatggagacc
gccttgaaacacattcagggaaaagccatcatcaattccataaaccttgaggatggagaa
gagcggtttgaaaaggtgacaaaactgatgaaagaatacggagcggcagtggtagttggg
acaatcgatgaaaaagggatgggggtttctgttgaaaggaaggtagaaattgctcaccgt
tcccacaaattattaactgagaaatatgggatctcatcagaagacattatctttgatccc
ctcgtctttccggttggcactggagatgatcagtatatcggatctgctgaagccacggtg
gaagggataaagaaaataaaggaagtcttaccgaaatgcccgcacatcttagggatcagt
aacgtttcgtttggcctgcctcctgttggcagagaggtgctgaacgctgtctatctttat
cattgtacaaaagcgggattggattatgcgattgtcaatacagaaaaactagaacgattc
gcctcgataccggatgaagaagtgaagatggcagaaaaattattatttaaaacttctgat
tcaagccttgctgaattcactgcctattatagggggaaaaagaaggaagtaaaggttccc
gtaaacacgatgaccctggaagaaagactgtcccattatgtagttgaagggacgaagcaa
gggcttgtcgacgaccttgagattgctcttcagaagtatgaatccccacttgatatcatt
aacggcccactgatggaagggatgagtgaagtagggagactatttaatgataaccagctg
attgtagcagaagtgttgcagagtgcggaggtcatgaaagcatctgttgcccatctggaa
ccacatatgaaacaaacggcaagttcatctacgaagggaaaggtcattttagccactgtc
aaaggggatgttcatgatattggaaagaatctcgttgatataatcctcagtaataatggt
tatgaggtgattgatttaggaataaaagtgtcaccacaacaactgatcgatgtcatcaag
gaagaaaagccagatattgttggattatccggcctccttgtgaaatcggcccagcaaatg
gtcatcacggcgaatgatttaaaacaatctgatatttccgtcccccttgtagtgggaggt
gctgccctcaccaggaaatttacaacgaataagatcgggatggaatatgatggtctggtg
ctttatgcaaaggatgccatggatggccttagtattatgaatggaattcagcatgcagaa
acaaggaaacgaatggaagaagaaagcattgaaaagcgaagcaagtttgtttcggttaga
gaatcaccggctcgaaaacaatctgcaacggcagtgatatcaagatcttcagttgcaaaa
gatgtaaaagttcatatcccggccgacttgttcccacatacgataaaagaattctcactg
gatcagattcaaccctatattaatcagcaaatgctgcttggtcatcatcttgggatcaaa
gggaaaatttcaagactattagaagaaggagacgagcgaacggtgggactgaaagctgtg
acggatgagctctttcagaaagctaaacaaaaagggatgattcaaggttcagcgaggtat
caattttttcctgcccaatctgatggggacgatgttatcatctatcatcctgatgatcca
tccgtggaaatggaacggtttcactttcctaggcagggaggtaatcaatgtttatgtctg
gcagattacttaagatctgtagagagtggtgaattggattatgtcggcttctttgccgta
acggctggtgtgaagatcagacagtgggcgaaagaattgaaagaagcggggcgattcctt
gaaagccatgctttgcaagcactagcattagaaacagcagaaggtctggctgagagggtg
catgaaatgatgaggagcaggtgggggtttcctgatcccgttgattttaccatgcaggac
cggttcaggactcattatcaagggcagagattttcatttggttatccagcctgcccggag
cttgaagatcaaaagaagttgttcaagcttattcaaccggaaaccattggaatccattta
accgatggctgcatgatggagcccgaagcgtccgtcacggcgatggttttcgctcatccg
gaagccagatattttaatgtattataa

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