Carlito syrichta (Philippine tarsier): 103259285 Help Entry 103259285         CDS       T07836                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism csyr  Carlito syrichta (Philippine tarsier) Pathway csyr04022   cGMP-PKG signaling pathway csyr04068   FoxO signaling pathway csyr04081   Hormone signaling csyr04140   Autophagy - animal csyr04150   mTOR signaling pathway csyr04151   PI3K-Akt signaling pathway csyr04152   AMPK signaling pathway csyr04211   Longevity regulating pathway csyr04213   Longevity regulating pathway - multiple species csyr04722   Neurotrophin signaling pathway csyr04910   Insulin signaling pathway csyr04920   Adipocytokine signaling pathway csyr04923   Regulation of lipolysis in adipocytes csyr04930   Type II diabetes mellitus csyr04931   Insulin resistance csyr04932   Non-alcoholic fatty liver disease csyr04935   Growth hormone synthesis, secretion and action csyr04960   Aldosterone-regulated sodium reabsorption csyr05010   Alzheimer disease csyr05206   MicroRNAs in cancer csyr05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:csyr00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     103259285 (IRS1)    04022 cGMP-PKG signaling pathway     103259285 (IRS1)    04151 PI3K-Akt signaling pathway     103259285 (IRS1)    04152 AMPK signaling pathway     103259285 (IRS1)    04150 mTOR signaling pathway     103259285 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     103259285 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103259285 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103259285 (IRS1)    04923 Regulation of lipolysis in adipocytes     103259285 (IRS1)    04920 Adipocytokine signaling pathway     103259285 (IRS1)    04935 Growth hormone synthesis, secretion and action     103259285 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     103259285 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     103259285 (IRS1)   09149 Aging    04211 Longevity regulating pathway     103259285 (IRS1)    04213 Longevity regulating pathway - multiple species     103259285 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     103259285 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     103259285 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     103259285 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103259285 (IRS1)    04932 Non-alcoholic fatty liver disease     103259285 (IRS1)    04931 Insulin resistance     103259285 (IRS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  103259285 NCBI-ProteinID:  XP_008055159 UniProt:  A0A1U7T528 LinkDB All DBs Position Unknown AA seq 1244 aa AA seqDB search MASPPESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGATAPGVGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPTQGGLT RRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSARLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPN GHYILSRGGNGHRYILGAGLGTSPALAGDEATNAADLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTHSYPEEGLEMHPLERRGGHHR PDSSTLHTDDGYMPMSPGVAPVPGSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDTGGGPSSSSSSAAPSGSGYGKLWTNGVGVHHSHALPHPKPPVESSG GKLLPCAGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGELEE GARHQHLRLSASSGRLLYATTAEDSSSSTSSDSLGGGYCGARPEPGLPHPHHQILQSHLP RKVDTAAQTNSRLVRPTRLSLGDPKASTLPRAREQQQPPPPPQPPLPHPSEPKSPGEYVN IEFGSDQPAYLSGPVASHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRATWQESA GVEIGRVGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPVAPVSYADMRTG IASEEVSLPRATAAASASSSAAATSSTAPQGTAELATRSSLLGGPQGPGGMSAFTRVNLS PNCNQSAKVIRADPQGCRRRHSSETFSSTPSSTRASNTVPFGAGAAIGGGGGGGSSSEDV KRHSSASFENVWLRPGEHGGALKEPTQVCGAAGGLENGLNYIDLDLVKDFKQRPQERPPQ PQPSPPTPPHQPLGSGESSSTRRSSEDLSAYASISFQKQPEDRQ NT seq 3735 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctccggagagcgacggcttctcggacgtgcgcaaggtgggctacctccgc aaacccaagagcatgcacaagcgctttttcgtgctgcgggcggccagcgaggctgggggc ccggcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgattcccctcgagagctgcttcaacatcaacaagcgggctgactccaagaac aagcacctggtggctctctacactcgggacgagcactttgccatcgctgcggacagcgag gcggagcaagacagctggtaccaggctctcctgcagctgcacaaccgcgccaagggccac cacgacggggccacggcacccggggtgggaggcggcgggggcagctgcagcggcagctcc ggcctcggcgaggctggggaggacttgagctacggggatgtgcctccaggaccggcgttc aaagaggtctggcaggtgatcctgaagcccaagggcctgggtcagacaaagaacctgatc ggcatctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaactcggag gcagcggctgtggtgctgcagctgatgaacatcaggcgctgcggccactcggagaacttc ttcttcattgaggtgggccgttctgctgtgacggggcctggcgagttctggatgcaggtg gatgactcggtggtggcccagaacatgcacgagaccatcctggaggccatgcgggccatg agcgacgagttccgtcctcgcagcaagagccagtcgtcgtccaactgctccaaccctatc agcgtccccctgcgcaggcaccatctcaacaaccccccccccacccagggggggctcacc cgccgatcacgcaccgagagcatcaccgccacctccccagccagcatggtgggtgggaag ccaggctccttccgcgtccgcgcctccagcgacggggaaggcaccatgtcccgcccggcc tcagtggacggcagccctgtgagtcccagcaccaataggacccacgcccaccggcatcgc ggcagtgcccggctacacccgccactcaaccatagccgctccatccccatgccatcttct cgctgctcgccttcggccaccagcccggtcagtctgtcgtccagcagtaccagtggccac ggctccacctcggactgcctcttcccacggcggtctagtgcttctgtgtccggttccccc agcgatggcgggttcatctcctcggatgagtatggctccagtccctgcgatttccgaagt tccttccgcagtgtcactccggactccctgggccacaccccgccggcccgcggtgaagag gagctgagcaactatatctgcatgggtggcaagggagcctctaccctgaccgcccccaac ggtcactacattttgtctcgcggtggcaatggccaccgctacatcctaggagctggcttg ggcacaagtccagccttggctggggatgaagcaaccaatgctgcagatctggataatcgg ttccgaaagaggactcactcggcaggcacatcccctaccatttcccaccagaagacccca tcccagtcctcagtggcttccattgaggagtatacagagatgatgcctgcctacccacca ggaggtggcagtggaggccgactgccgggccaccggcactctgccttcgtgcccacccac tcctaccccgaggagggtctggaaatgcaccccttggagcgtcgggggggccaccatcgt ccggacagctccaccctccacactgatgatggctacatgcccatgtccccaggggtggcc ccagtgccgggcagccgaaagggcagtggggactatatgcccatgagccccaagagcgtg tctgccccacagcagatcatcaaccccatcagacgccatccccagagagtggaccccaat ggctacatgatgatgtcccccagtggcagttgctcccctgacactggaggtggacccagc agcagcagcagcagtgctgctccttcggggagcggctatgggaagctgtggacaaatggg gtaggggtccaccactctcatgccctgcctcatcccaaacccccagtggagagcagtggt ggcaagctcttgccttgcgcaggtgactacatgaacatgtcaccagtgggggactcgaac accagcagcccctctgactgctactatgggcctgaggacccccagcacaagccagtcctc tcctactactcattgccaaggtccttcaagcacacccagcgccctggggagctggaggag ggtgcccggcaccagcacctccgcctttccgctagctctggtcgccttctctatgctaca acagcagaagattcttcctcatccaccagcagtgacagcctgggtgggggatactgtggt gctaggccggagcctggcctcccacatccccaccatcagatcctgcagtcccatctgcct cgaaaggtggacacggctgcccagaccaacagccgcctggttcggcccacaaggctgtcc ctgggggatcccaaggccagcaccttacctcgggcccgtgagcagcagcagccgccgccg ccgcctcagcctcctctgccgcacccttcagagcccaagagcccaggggaatatgtgaat attgaatttgggagtgatcagcctgcctacttatctggccctgtggcttcacacagctca ccttctgtcaggtgcccatcccagctccagccagctcccagagaagaagagactggcact gaggagtacatgaaaatggatctcgggccaggccggagggctacctggcaggagagtgcc ggggtcgagataggcagagtgggtcctgcacctcctggggctgctagcatttgcaggcct acccgggcggtgcccagcagccggggtgactacatgaccatgcagatgagttgtccccgt cagagctacgtggacacgtcaccagtcgcccctgtcagttatgctgacatgcggacaggc attgcttcagaggaggtgagcctgcccagggccactgcagctgcatctgcctcatcctcc gcagctgctacttcctccactgcgcctcaagggacagctgagctggctacccgctcatcc ctgctggggggcccacagggacccgggggcatgagcgccttcactcgggtgaacctcagt cccaactgcaaccagagtgccaaagtgatccgtgcagacccgcaagggtgccggaggagg catagctccgagaccttctcctccacacctagttccactcgggcaagcaacacggtgccc ttcggagcaggggctgccatagggggcggtggcggtggcggcagcagcagtgaggatgta aaacgccacagctctgcttcctttgagaacgtctggctgaggcctggggagcatggggga gcccttaaggagccaacccaagtatgtggggctgctgggggtttggagaatggtcttaac tacatagacctggatttggtcaaggacttcaaacagcgccctcaggagcgtccccctcag ccgcagccttccccgcctacaccccctcatcagcccctgggcagtggtgagagcagctcc acccgccgctccagtgaggatttaagcgcctatgccagcatcagtttccagaagcagcca gaggaccgccagtag

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