Cuculus canorus (common cuckoo): 104055667
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Entry
104055667 CDS
T08597
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
cuca
Cuculus canorus (common cuckoo)
Pathway
cuca00140
Steroid hormone biosynthesis
cuca01100
Metabolic pathways
Module
cuca_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
cuca_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
cuca_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
cuca00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
104055667
Enzymes [BR:
cuca01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
104055667
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
104055667
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Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
NmrA
KR
Semialdhyde_dh
Motif
Other DBs
NCBI-GeneID:
104055667
NCBI-ProteinID:
XP_009555122
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Position
1:124747694..124760251
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AA seq
377 aa
AA seq
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MSLAGVSCLVTGAGGFLGQRIVQLLLEEEEPLAEIRLLDKTFSNETLRRFEKLQGKTEVK
ILEGDIRDVMFLHRACQGVSLIIHTASIIDTLGLVEKQLLWEVNVTGTQLLLEVCVRCNV
QHFIYTSTIEVTGPNWKGDPVFSGDEDTVYVSVPKFPYAQTKRLAENSVLKADGQVLKDG
GTLMTCALRSMYIFGEGCPFLQGHLDKCLLNKNVYLRFSRKEALVNPVYVGNIAWAHVQA
AKALRVPQKAENIRGQFYYISDDTPHMSYADLNYELTKDLGFAIEPRLPMPLTVLYYFSL
LLEIVSFLLRPFVRYIPSTNRHLVTLLNTPFTFSYKKAQKDFGYTPRYSWEAAKQSTGQW
LASIVPQRREYLRIETV
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgtccctggctggggtaagctgtctggtgacaggagcaggaggatttcttggccagagg
attgtccagttgctgttggaagaagaagagccgctggcagagatccgactgctggacaaa
acctttagcaatgaaacactcaggagatttgaaaagctccagggtaagactgaggtgaaa
atcctggaaggcgacatccgagatgtgatgttcctgcaccgtgcctgtcagggggtctcc
ctcatcatccacacagcttccatcattgacaccttgggcctcgtagagaagcagttgctc
tgggaagtgaatgtgacaggtactcagctactgctggaggtatgtgtccgctgtaacgtc
cagcacttcatatataccagtaccatagaagtcacaggcccaaactggaaaggtgaccca
gttttcagtggtgatgaagatacagtttatgtgagcgtaccaaaatttccttacgcccag
actaagagactggcagagaattcagtgctgaaagcagatggtcaggtgttaaaggatggt
ggcacactgatgacttgtgccctgagatcaatgtacatttttggagaaggatgcccattt
cttcaaggtcatctcgataagtgtctgttaaacaaaaatgtttacctgcgcttctccaga
aaggaggctttggtgaaccctgtgtatgtggggaacattgcctgggcacatgtgcaggca
gccaaagccctgcgggttccacagaaagccgagaacatcagggggcaattctactacatc
tcagatgacactcctcatatgagctatgcagatctaaattatgagctgaccaaggacctg
gggtttgcaattgagcccaggctccccatgcctttgacagtgttgtattacttctcgctg
ctgctggagatcgtgagcttcttgctcaggccctttgtcaggtacatcccctccaccaac
cgtcacctggtcactctactgaacaccccattcaccttctcttataaaaaggcacagaaa
gattttggctacacaccccgctactcatgggaagcagccaagcaatccactggtcagtgg
cttgcctccattgtcccacagagaagggagtacttgcgaatcgagactgtctaa
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