Cupriavidus sp. KK10: KB879_11260
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Entry
KB879_11260 CDS
T08941
Symbol
mdeB
Name
(GenBank) alpha-ketoglutarate dehydrogenase
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
cuk
Cupriavidus sp. KK10
Pathway
cuk00010
Glycolysis / Gluconeogenesis
cuk00020
Citrate cycle (TCA cycle)
cuk00620
Pyruvate metabolism
cuk00785
Lipoic acid metabolism
cuk01100
Metabolic pathways
cuk01110
Biosynthesis of secondary metabolites
cuk01120
Microbial metabolism in diverse environments
cuk01200
Carbon metabolism
cuk01210
2-Oxocarboxylic acid metabolism
Module
cuk_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cuk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
KB879_11260 (mdeB)
00020 Citrate cycle (TCA cycle)
KB879_11260 (mdeB)
00620 Pyruvate metabolism
KB879_11260 (mdeB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KB879_11260 (mdeB)
Enzymes [BR:
cuk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
KB879_11260 (mdeB)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QUN30442
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All DBs
Position
2332764..2335460
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AA seq
898 aa
AA seq
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MTDLGSPHARLLAQAMPEGDNDPQETREWLDALEAVVAQCGQERARFLLSRLLDAAPALG
VSTTAQSNTPYLNTIPVERQPPYPGDLAMEARITGIVRWNALAMVVRANQAYGELGGHIS
SYASAADLFEVGFNHFFQGADAGNGGDLVYFQPHSAPGVYARAFLEGRLSEAQLDNFRRE
AGGQGLCSYPHPWLMPDFWQFPTGSMGLGPIQSVYQARFMRYLEHRGLQATSGRHVWGVF
GDGEMDEPESIAALPLAAREKLDNLTFVINCNLQRLDGPVRGNGQIVQELEALFRGAGWN
VIKVLWGSAWDPIFARDHSGALLRAFASTMDGQFQTYKAKDGHYGREHFFGQNEALKALV
AHMTPEEVAALNRGGHDLRKLHAAFAAARAHKGQPTVILAKTIKGYGMGNAGQAQNTTHQ
QKKLDLEALKVFRSRFGLDLSDEDLESMRFYRPAEDSAELRYLRERRQALGGYLPARRRQ
ADAVPVPPLAKYGQFAVDAGQKEMSTTMAMVRMLTGLLKDKTLGPRVVPIVADEARTFGM
ASLFRQVGIYSSQGQLYEPEDAGSMLYYREDIRGQILEEGITEAGAMSSWIAAGTAYSTH
GTAMLPLYIYYSMFGFQRIGDLIWAAGDQRARGFLVGATAGRTTLSGEGLQHQDGTSHII
AATIPNCRAYDPAYAYELAVIVDAGMRAMMERQEDVFYYLTVMNENYAQPSMPAGVERDI
VRGMYRLAQVAGGGRARVRLLGSGTILREVEAAARMLAEDWQVDSEVFSVTSFSELEREA
RETARQRLHHPQDSIAPSHVEALLAGDAPVVAATDYVRAYPQLIAPYVPAPFTVLGTDGY
GRSDNRPSLRRFFEVDRAYVCVAALRALAAQGTVPASVVAEAIARYGIDTDKPAPSSL
NT seq
2697 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccttggctccccacacgcccggctgctcgcccaagccatgcccgagggcgac
aacgatccgcaggagacgcgcgaatggctggacgcgctcgaggcggtggtggcgcaatgc
gggcaggagcgcgcgcgcttcctgctcagccggctgctcgatgccgcgcccgcgctgggt
gtgtcgaccacggcgcaaagcaacacgccttacctgaacaccatcccggtcgagcgccag
cccccttatccgggcgatctggcgatggaagcgcgcatcaccggcatcgtgcgctggaat
gcccttgccatggtggtgcgcgccaaccaggcctacggtgagctgggtgggcatatctcc
agctatgcctcggcggcggacctgttcgaggtcggcttcaaccacttcttccagggcgcc
gatgccggcaacggcggcgacctggtctacttccagccgcactcggcaccgggcgtgtac
gcacgcgccttcctggaagggcgcctgtccgaagcccagctcgacaacttccgccgcgag
gcgggcgggcagggcctgtgctcgtatccgcacccctggctgatgccggacttctggcaa
ttcccgaccggttcgatggggctgggcccaatccagtcggtctaccaggcgcgcttcatg
cgctacctggagcaccgggggctgcaggccacttcgggccggcacgtgtggggcgtgttc
ggcgacggcgagatggacgagcccgaatcgatcgccgcgctgccgctggcggcgcgcgag
aaactcgacaacctgacctttgtcatcaactgcaacctgcagcgcctggacgggccggtg
cgcggcaacggccagatcgtgcaggagctggaagcgctgttccgcggcgccggctggaac
gtgatcaaggtgctgtggggcagcgcctgggacccgatcttcgcgcgcgatcactccggc
gcgttgctgcgcgccttcgcctcgaccatggacggccagttccagacctacaaggccaag
gacggccactacgggcgcgagcatttcttcggccagaacgaagcgctgaaggcgctggtc
gcccatatgacgccggaagaggtggccgcgctgaaccgcggcgggcacgacctgcgcaag
ctccatgcggcctttgccgcggcacgcgcgcacaaggggcagcccaccgtgatcctggcc
aagaccatcaagggctatggcatgggcaatgccggccaggcgcagaacaccacgcaccag
cagaagaagctggatctcgaggcgctgaaggtgttccgcagccgcttcggcctggacttg
tccgacgaggacctggaatcgatgcgcttctaccgccctgccgaggacagcgccgagctg
cgctacctgcgcgagcgccgccaggccctgggcggctacctgccggcgcgtcggcgccag
gccgacgccgtgccggtgccgccgctggcgaaatacggccagttcgccgtggacgctggc
cagaaggaaatgtcgaccaccatggcgatggtgcgcatgctgactggtctgctcaaggac
aagacactcggcccgcgcgtggtgcccatcgtcgccgacgaggcgcgcacctttggcatg
gccagcctgttccgccaggtcggcatctattcgtcgcagggccagttgtacgagcccgag
gacgccggctcgatgctgtactaccgcgaggacatccgcggccagatcctggaagagggc
atcaccgaggccggtgcgatgtcgtcgtggattgccgcgggcactgcctacagcacccat
ggcacggccatgctgccgctctatatctactactcgatgttcggcttccagcgcatcggc
gacctgatctgggccgccggcgaccagcgtgcgcgcggcttcctggtgggcgccacggcc
ggccgcaccacgctgtcgggcgaagggctgcagcaccaggacggcaccagccacatcatt
gccgccaccatccccaactgccgtgcctatgacccggcctatgcctatgaactcgcggtg
atcgtcgacgcgggcatgcgcgcgatgatggagcgccaggaggacgtgttctattacctg
accgtgatgaacgagaactacgcccagccgtcgatgccggccggcgtggagcgcgacatc
gtgcgcggcatgtaccggcttgcgcaggtggcagggggcgggcgcgccagggtgcggctg
ctcggcagcggcaccatcctgcgcgaggtggaggccgcggcgcggatgctggccgaggac
tggcaggtcgacagcgaggtgttcagcgtcaccagcttctccgagctggagcgcgaggcg
cgcgagaccgcgcgccaacgcctgcatcatccgcaggacagcatcgcccccagccatgtg
gaagcgctgctggccggcgacgccccggtggtggcggccaccgactacgtgcgcgcctat
ccgcagctgattgcgccctatgtgccggcccccttcacggtgctgggcaccgacggctat
ggccgcagcgacaaccggccgtcgctgcgccgcttcttcgaggtcgatcgcgcctatgtc
tgcgtggcggcgctgcgcgcgcttgcggcgcagggcacggtgccggcgtcggtggtggcc
gaggcgatcgcgcgctacggcatcgacacggacaagcctgcgccgtcctcgctctga
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