Cupriavidus sp. Agwp_2: LPA45_28375
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Entry
LPA45_28375 CDS
T11307
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
cupa Cupriavidus sp. Agwp_2
Pathway
cupa00909
Sesquiterpenoid and triterpenoid biosynthesis
cupa01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
cupa00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
LPA45_28375 (shc)
Enzymes [BR:
cupa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
LPA45_28375 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
LPA45_28375 (shc)
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Pec_lyase
Motif
Other DBs
NCBI-ProteinID:
XDA02616
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Position
pCCF_large:complement(2344212..2346257)
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AA seq
681 aa
AA seq
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MSMKETDFATTATPIQFAADPAFGPAAGPAAPQSAAQALDHGIGLAVDALLHQQRPDGHW
VYELEADATIPAEYVLMVHYLGEAPDLALEARIARYLRRIQNPDGGWPLFHEGRPDLSAS
VKAYFALKMAGDDPQAPHMARARQAIHAMGGAEASNVFTRTLLALYGVMSWSAVPMMPVE
IMLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPRARNPRHVGIDELFANQHHGAGLAPR
APHQHAGWYNVFRGLDALLRVAEPVFPRLLRRRAIAAAQTFVRERLNGEDGLGAIFPAMA
NSVMMFDVLGVPADDPARAVARRSVERLLVEHGDEAYCQPCLSPVWDTALAAHALLETGE
ARAAEAVGRGLEWLKPLQVLDVRGDWTVRRPRVRPGGWAFQYANPHYPDVDDTAVVVAAM
DRYMREHAAPGRYDEAAARAAEWIVGMQSGNGGWGAFEPENTHLYLNNIPFADHGALLDP
PTADVSARCLSMLCQIGATPARSEPAARALRYLLAEQMADGSWFGRWGTNYIYGTWSALC
ALNAAGMGSDAPAVRRATEWLAGIQNEDGGWGEDGSSYRLDYRGYETAPSVASQTAWALL
ALMAAGAVQHPAVARGIGYLLRTQRPPQEGGLWQEPRFTAVGFPRVFYLRYHGYARYFPL
WALARYRNLQRGGGGRVTWGL
NT seq
2046 nt
NT seq
+upstream
nt +downstream
nt
atgtcgatgaaggagaccgacttcgccacgacagccacaccaatccagttcgccgctgat
cccgctttcggtccggcggctggtcccgccgcgccacaatcggccgcacaggcactcgac
cacggcatcggtctcgcggtcgatgcgctgctgcaccagcagcgccccgatggccactgg
gtctacgaactggaagccgacgccaccatcccggccgaatacgtgctgatggtgcactac
ctgggcgaggcgcccgacctggcgctggaagcgcgcatcgctcgctacctgcgccgcatc
cagaaccccgacggcggctggccgctgttccatgaaggccggccggatctcagcgccagc
gtgaaggcgtacttcgcgctgaaaatggccggcgacgatccgcaggcgccgcatatggcg
cgcgcgcgccaggccatccatgccatgggcggcgccgaggccagcaacgtgtttacgcgc
acgctgctggcactgtacggcgtgatgtcgtggtcggcggtgccgatgatgccggtggaa
atcatgctgctgccgcgctggttccccttccacctgtccaaggtttcttactgggcgcgc
acggtgatcgtgccgctgctggtgctgaacagcctgcgcccgcgcgcgcgcaacccgcgc
cacgtcggcatcgacgaactcttcgccaaccagcaccacggcgcgggcctggcgccgcgc
gcgccgcaccagcatgccggctggtacaacgtattccgcgggctcgacgcgctgctgcgc
gtggccgagccggtgttcccgcgtctgctgcgccggcgcgccatcgccgcggcgcaaacc
ttcgtgcgcgagcggctgaacggcgaggacggcctcggcgcgatcttcccggcgatggcc
aacagcgtgatgatgttcgacgtgctcggcgtgccggccgatgatcccgcgcgcgcggtg
gcgcggcgctcggtcgagcggctgctggtggagcacggggacgaggcctactgccagccc
tgcctgtcgccggtgtgggacaccgcgctggccgcgcacgcgctgctcgagaccggcgag
gcgcgcgcggctgaagccgtggggcgcggactggaatggctcaagccgctgcaggtgctg
gatgtgcgcggcgactggaccgtgcgccgcccgcgggtgcgcccgggcggctgggctttc
cagtacgccaacccgcattacccggatgtcgacgacaccgccgtggtggtggcggcgatg
gaccgctacatgcgcgaacacgccgcgccgggccgctacgacgaagcggcggcgcgcgcg
gccgaatggatcgtcggcatgcagagcggcaacggcggctggggcgcgttcgagcccgag
aacacgcacctctacctgaacaacatccccttcgccgatcacggcgcgctgctcgacccg
cccaccgcggacgtctcggcgcgctgcctgtcgatgctgtgccagattggcgccacgccg
gcccgcagcgagcccgcagcacgcgccctgcgctacctgctggccgagcagatggcggat
ggcagctggttcggccgctggggcaccaactacatctacggcacctggagcgcactgtgc
gcgctgaacgccgccggcatgggatccgacgcgcccgccgtgcggcgcgccaccgagtgg
ctggccgggatccagaacgaagacggcggctggggcgaagacggcagcagctaccggctc
gactaccgcggctatgaaacggcgcccagcgtggcatcgcagactgcctgggccttgctg
gcgctgatggcggccggcgccgtgcagcatcccgccgtcgcgcgcggcattggctacctg
ctgcgcacgcagcgtccgccgcaggagggcggactctggcaggagccgcgcttcactgcg
gtcggcttcccgcgcgtgttctacctgcgctatcacggctatgcgcgctattttccgctg
tgggcgctggcgcgctaccgcaacctgcagcgcggtggtggcggccgcgtgacatggggc
ctgtga
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