Congregibacter variabilis: R0135_02980
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Entry
R0135_02980 CDS
T10777
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
cvb Congregibacter variabilis
Pathway
cvb00270
Cysteine and methionine metabolism
cvb00450
Selenocompound metabolism
cvb00670
One carbon pool by folate
cvb01100
Metabolic pathways
cvb01110
Biosynthesis of secondary metabolites
cvb01230
Biosynthesis of amino acids
cvb04980
Cobalamin transport and metabolism
cvb04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
cvb00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
R0135_02980 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
R0135_02980 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
R0135_02980 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
R0135_02980 (metH)
04980 Cobalamin transport and metabolism
R0135_02980 (metH)
Enzymes [BR:
cvb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
R0135_02980 (metH)
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
DUF2779
Motif
Other DBs
NCBI-ProteinID:
WOJ94142
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Position
659213..662878
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AA seq
1221 aa
AA seq
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MNSFSPVPGPLADALRDRILVIDGAMGTMIQAEGLQEADYRGERFADHPGDLKGNNDLLS
ITRPEVIEGIHTAYLQAGADIIETNTFNATAVALEDYGLQAIARELNETSARIARRAADA
MSAETPEKPRFVAGVLGPTPRTASISPDVNDPGARNVDFARLSEDYSEAVGGLLDGGVDL
LMIETIFDTLNAKAAIFAIESVFEERGIRLPVMISVTFPDVSGRNLSGQSPTAFWYSVAH
ARPLVVGSNCGRRFLEVRPFLEELSKATEGYFSAHLNAGLPNAFGEYDEAPEVMAGEFRD
FAERGFVNLVGGCCGTTPAHIRAIAHAVEGIAPRVLPENPRACQLSGLEPFTFNADSLFV
NVGERCNVTGSARFKKLVLSGDYETALDVARTQVEDGAQIIDINMDEGMLDAKEAMVTFL
NLIASEPDISRVPIMIDSSRWEVIEAGLRCVQGKAVVNSISLKAGEEEFLEQARLCQRYG
AAVVVMAFDEDGQADTIARRQEICQRSWDLLLERLDFNPDDIIFDPNIFAVATGIELHNT
YAVDFIEATRWIKENLPGAKVSGGVSNVSFSFRGNNPVREAIHSVFLYHAIRAGMDMGIV
NAGQLAVYDELPEELREAVEDVVLNRRDDSTERLLDIASKYHADGPATVRVEDLAWRDEP
VTKRLEYALVKGINSYIEEDAEEARQQATRPIEVIEGPLMDGMNVVGDLFGQGKMFLPQV
VKSARVMKQAVAYLQPYIEEEKAEGSTNGRILMATVKGDVHDIGKNIVGVVLQCNNYEVI
DLGVMVHCEEILRVAKEKNVDIIGLSGLITPSLDEMMHVASEMQRTGFSVPLMIGGATTS
KAHTAVKIEPNYQNDLVVYVPDASRSVSVASLLLGEQKAGFVSERREEYVQVRERIANRK
PKAKRLPYDKALANRAVFDWESYQPPTPSFTGVRVFKNIPLQDLVDTIDWTPFFITWELA
GKYPKILEDDVVGEQARDLFADAQAMLKKIVEEDWLEACAVVGFWPAHSDGEDVLVDTGD
ETAPLRLHHLRQQTEKANDQPNLSLSDYVAPANDYIGGFCVTTGHGVSQRAAAFEANHDD
YNSIMLKALADRLAESLAEHMHLRVRQEFWGYAANEQLSNEDLIRERYRGIRPAPGYPAC
PDHTEKRALFNLLDAEERCGVTLSDNYAMEPASSVSGWYFSHPDARYFAVGKIGEDQLES
IATRKGVKTAALARWLAPNLD
NT seq
3666 nt
NT seq
+upstream
nt +downstream
nt
atgaactcctttagcccagtacccggtccccttgcggacgctcttcgcgatcgaattctt
gtgatagacggggccatggggaccatgatccaggcggaaggcctgcaggaagcagactat
cgcggcgagcgctttgccgatcaccctggcgacctcaaaggcaataatgacctgctctcg
ataacccgtccggaggtcattgaaggcattcatacagcctacctgcaggccggcgctgac
attatcgaaaccaacacctttaacgccacagctgtagcgctggaagattacggcttgcag
gccattgcccgagaattgaacgagacatcggcacgtatcgcccgacgcgctgccgatgcc
atgagcgcagagacccccgaaaagccacgctttgtagccggcgtacttgggcccacaccg
cgtaccgcatctatttcaccggacgtaaacgatccgggtgctcgaaatgttgatttcgcc
cgtctgagcgaggattactcagaagccgttgggggcctcctagacggtggcgttgatctt
ttaatgatcgaaaccatcttcgacacactgaatgccaaggcggctatctttgctatcgag
agcgtgttcgaggaacgcggtattcgtcttcctgtgatgatttccgtcactttcccggat
gttagcggcaggaatctgtcgggacagagtcccacggcattttggtactccgttgcacac
gcgcggcctttggtcgtgggaagtaactgcggcagacgattccttgaagtgcgcccgttt
cttgaagaactctccaaagccaccgaaggttatttcagcgcccatctcaatgcgggactt
cccaatgcctttggagagtacgacgaagcgccagaagttatggctggggaattcagagac
ttcgcggagcggggatttgtaaatcttgtcggtggctgttgtggcactacgcctgcgcac
atccgcgctattgcccacgcggttgaaggaattgctccgagagtgcttccagaaaacccc
cgggcctgtcagctcagtggactcgagccttttacctttaatgcagacagtctatttgta
aatgtcggtgagcgctgcaatgtcaccggctctgcccgcttcaaaaagctcgtgttgtcc
ggagattacgaaaccgcgctggatgtcgcgcgcacccaggttgaggacggcgctcaaatc
atcgatatcaacatggacgaaggcatgctcgatgccaaagaagccatggtgacttttctc
aatctgattgcatcagagccggacatttcccgcgtaccgatcatgattgactcttcgcgc
tgggaagtgatcgaagcgggtttgcgctgcgtgcagggtaaggctgttgtgaactcgatt
agccttaaagccggtgaagaggagtttctggagcaggcaagactgtgtcagcgctatggc
gcagccgtagtagtcatggccttcgatgaagacggccaggccgacaccatcgcccgccga
caggaaatctgtcagcgaagctgggacttgctgcttgagcgtttggacttcaatcctgat
gatattatttttgacccgaatattttcgcggttgccacgggtatcgagcttcataacacc
tacgccgtagattttatcgaggcaactcgctggattaaggaaaaccttcccggggccaaa
gtatcgggcggtgtatccaacgtgtctttctccttccgggggaacaaccccgtgcgcgag
gctattcactcggtgtttctgtatcacgcgattcgtgccggcatggacatgggaatcgtc
aacgctgggcagctggcggtttatgacgagctccccgaggaattgcgtgaggctgtagaa
gacgttgtactgaaccgccgggacgacagcacggaacgcctactcgatatcgccagcaaa
tatcacgcagacgggcccgctacggtgcgtgtcgaagatcttgcctggcgcgacgagccg
gtgacgaagcgcctcgaatacgccctggtcaagggcatcaatagctatatcgaagaagat
gcggaagaagcccggcaacaggccacacgccccattgaagttatcgaaggtccgctcatg
gacggcatgaatgtcgtcggtgatctttttggtcagggcaaaatgtttcttccccaggta
gttaaaagcgcgcgggtgatgaagcaagctgtggcttacctgcagccgtatatcgaagaa
gaaaaagccgagggcagcaccaacggcagaatcctcatggccacggttaagggcgatgtc
catgacattggcaaaaacattgtcggcgtcgtgcttcagtgcaataactatgaggttatt
gatctgggggtaatggtgcattgcgaggaaatactgcgtgtcgccaaagagaaaaacgtc
gatattattggtctgagcggtctcatcactccgtcccttgacgaaatgatgcatgttgcc
agcgaaatgcagcgcacgggtttctcggtcccgctaatgatcggtggcgccaccacttcc
aaggcgcacaccgcggtcaagatcgagcccaactatcaaaatgacctggtggtgtacgtg
ccggatgcatcccgaagtgtatcggtggcgtccctgttactgggtgagcaaaaggctgga
ttcgtcagcgagcgacgagaagaatacgtgcaggttcgagagcgtatcgctaaccgcaag
ccaaaggccaagcgcctgccctatgacaaagccctggccaaccgcgctgtatttgattgg
gagagctaccaaccacccacgccgagctttaccggtgtccgggtgtttaagaatattccc
ttacaggatctggtcgacactattgactggactcccttcttcatcacctgggagcttgcg
ggcaaataccccaagatactcgaggatgatgtagtcggtgaacaagccagagacctgttt
gcagacgcacaggccatgctcaagaaaattgttgaagaggactggctggaggcttgtgca
gtcgtcggcttctggcctgctcacagcgatggcgaagacgttctggtagataccggggac
gagactgctccgctacgcttgcatcatctgcgacaacaaaccgaaaaagccaacgatcaa
ccgaatctgagtctcagtgactatgtggccccggcaaatgattacatcggtggtttctgt
gttacgacgggtcacggtgtttcccagcgtgctgctgcctttgaagcgaaccatgatgac
tacaattcgatcatgctcaaggccttggccgatcgattggcagagtcactggctgaacat
atgcacctgcgtgttcgccaggaattctggggctatgcagcgaatgaacagctatcaaac
gaggatttgatcagggagcgctatcggggcatacgccctgctcctggttaccctgcctgt
cctgatcacaccgagaagcgagctttgttcaacttgctggacgctgaagagcgctgcggg
gtgacgctgtctgataactacgccatggagccggcatcgtcggtgagcggttggtacttc
tcacacccggatgcacgatactttgccgtagggaaaattggcgaagatcagcttgaatcg
atcgcgacgcgtaagggtgtgaagacggccgcactggctcgctggctggctcccaacctc
gactaa
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