KEGG   Congregibacter variabilis: R0135_02980
Entry
R0135_02980       CDS       T10777                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
cvb  Congregibacter variabilis
Pathway
cvb00270  Cysteine and methionine metabolism
cvb00450  Selenocompound metabolism
cvb00670  One carbon pool by folate
cvb01100  Metabolic pathways
cvb01110  Biosynthesis of secondary metabolites
cvb01230  Biosynthesis of amino acids
cvb04980  Cobalamin transport and metabolism
cvb04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:cvb00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    R0135_02980 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    R0135_02980 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    R0135_02980 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    R0135_02980 (metH)
   04980 Cobalamin transport and metabolism
    R0135_02980 (metH)
Enzymes [BR:cvb01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     R0135_02980 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding DUF2779
Other DBs
NCBI-ProteinID: WOJ94142
LinkDB
Position
659213..662878
AA seq 1221 aa
MNSFSPVPGPLADALRDRILVIDGAMGTMIQAEGLQEADYRGERFADHPGDLKGNNDLLS
ITRPEVIEGIHTAYLQAGADIIETNTFNATAVALEDYGLQAIARELNETSARIARRAADA
MSAETPEKPRFVAGVLGPTPRTASISPDVNDPGARNVDFARLSEDYSEAVGGLLDGGVDL
LMIETIFDTLNAKAAIFAIESVFEERGIRLPVMISVTFPDVSGRNLSGQSPTAFWYSVAH
ARPLVVGSNCGRRFLEVRPFLEELSKATEGYFSAHLNAGLPNAFGEYDEAPEVMAGEFRD
FAERGFVNLVGGCCGTTPAHIRAIAHAVEGIAPRVLPENPRACQLSGLEPFTFNADSLFV
NVGERCNVTGSARFKKLVLSGDYETALDVARTQVEDGAQIIDINMDEGMLDAKEAMVTFL
NLIASEPDISRVPIMIDSSRWEVIEAGLRCVQGKAVVNSISLKAGEEEFLEQARLCQRYG
AAVVVMAFDEDGQADTIARRQEICQRSWDLLLERLDFNPDDIIFDPNIFAVATGIELHNT
YAVDFIEATRWIKENLPGAKVSGGVSNVSFSFRGNNPVREAIHSVFLYHAIRAGMDMGIV
NAGQLAVYDELPEELREAVEDVVLNRRDDSTERLLDIASKYHADGPATVRVEDLAWRDEP
VTKRLEYALVKGINSYIEEDAEEARQQATRPIEVIEGPLMDGMNVVGDLFGQGKMFLPQV
VKSARVMKQAVAYLQPYIEEEKAEGSTNGRILMATVKGDVHDIGKNIVGVVLQCNNYEVI
DLGVMVHCEEILRVAKEKNVDIIGLSGLITPSLDEMMHVASEMQRTGFSVPLMIGGATTS
KAHTAVKIEPNYQNDLVVYVPDASRSVSVASLLLGEQKAGFVSERREEYVQVRERIANRK
PKAKRLPYDKALANRAVFDWESYQPPTPSFTGVRVFKNIPLQDLVDTIDWTPFFITWELA
GKYPKILEDDVVGEQARDLFADAQAMLKKIVEEDWLEACAVVGFWPAHSDGEDVLVDTGD
ETAPLRLHHLRQQTEKANDQPNLSLSDYVAPANDYIGGFCVTTGHGVSQRAAAFEANHDD
YNSIMLKALADRLAESLAEHMHLRVRQEFWGYAANEQLSNEDLIRERYRGIRPAPGYPAC
PDHTEKRALFNLLDAEERCGVTLSDNYAMEPASSVSGWYFSHPDARYFAVGKIGEDQLES
IATRKGVKTAALARWLAPNLD
NT seq 3666 nt   +upstreamnt  +downstreamnt
atgaactcctttagcccagtacccggtccccttgcggacgctcttcgcgatcgaattctt
gtgatagacggggccatggggaccatgatccaggcggaaggcctgcaggaagcagactat
cgcggcgagcgctttgccgatcaccctggcgacctcaaaggcaataatgacctgctctcg
ataacccgtccggaggtcattgaaggcattcatacagcctacctgcaggccggcgctgac
attatcgaaaccaacacctttaacgccacagctgtagcgctggaagattacggcttgcag
gccattgcccgagaattgaacgagacatcggcacgtatcgcccgacgcgctgccgatgcc
atgagcgcagagacccccgaaaagccacgctttgtagccggcgtacttgggcccacaccg
cgtaccgcatctatttcaccggacgtaaacgatccgggtgctcgaaatgttgatttcgcc
cgtctgagcgaggattactcagaagccgttgggggcctcctagacggtggcgttgatctt
ttaatgatcgaaaccatcttcgacacactgaatgccaaggcggctatctttgctatcgag
agcgtgttcgaggaacgcggtattcgtcttcctgtgatgatttccgtcactttcccggat
gttagcggcaggaatctgtcgggacagagtcccacggcattttggtactccgttgcacac
gcgcggcctttggtcgtgggaagtaactgcggcagacgattccttgaagtgcgcccgttt
cttgaagaactctccaaagccaccgaaggttatttcagcgcccatctcaatgcgggactt
cccaatgcctttggagagtacgacgaagcgccagaagttatggctggggaattcagagac
ttcgcggagcggggatttgtaaatcttgtcggtggctgttgtggcactacgcctgcgcac
atccgcgctattgcccacgcggttgaaggaattgctccgagagtgcttccagaaaacccc
cgggcctgtcagctcagtggactcgagccttttacctttaatgcagacagtctatttgta
aatgtcggtgagcgctgcaatgtcaccggctctgcccgcttcaaaaagctcgtgttgtcc
ggagattacgaaaccgcgctggatgtcgcgcgcacccaggttgaggacggcgctcaaatc
atcgatatcaacatggacgaaggcatgctcgatgccaaagaagccatggtgacttttctc
aatctgattgcatcagagccggacatttcccgcgtaccgatcatgattgactcttcgcgc
tgggaagtgatcgaagcgggtttgcgctgcgtgcagggtaaggctgttgtgaactcgatt
agccttaaagccggtgaagaggagtttctggagcaggcaagactgtgtcagcgctatggc
gcagccgtagtagtcatggccttcgatgaagacggccaggccgacaccatcgcccgccga
caggaaatctgtcagcgaagctgggacttgctgcttgagcgtttggacttcaatcctgat
gatattatttttgacccgaatattttcgcggttgccacgggtatcgagcttcataacacc
tacgccgtagattttatcgaggcaactcgctggattaaggaaaaccttcccggggccaaa
gtatcgggcggtgtatccaacgtgtctttctccttccgggggaacaaccccgtgcgcgag
gctattcactcggtgtttctgtatcacgcgattcgtgccggcatggacatgggaatcgtc
aacgctgggcagctggcggtttatgacgagctccccgaggaattgcgtgaggctgtagaa
gacgttgtactgaaccgccgggacgacagcacggaacgcctactcgatatcgccagcaaa
tatcacgcagacgggcccgctacggtgcgtgtcgaagatcttgcctggcgcgacgagccg
gtgacgaagcgcctcgaatacgccctggtcaagggcatcaatagctatatcgaagaagat
gcggaagaagcccggcaacaggccacacgccccattgaagttatcgaaggtccgctcatg
gacggcatgaatgtcgtcggtgatctttttggtcagggcaaaatgtttcttccccaggta
gttaaaagcgcgcgggtgatgaagcaagctgtggcttacctgcagccgtatatcgaagaa
gaaaaagccgagggcagcaccaacggcagaatcctcatggccacggttaagggcgatgtc
catgacattggcaaaaacattgtcggcgtcgtgcttcagtgcaataactatgaggttatt
gatctgggggtaatggtgcattgcgaggaaatactgcgtgtcgccaaagagaaaaacgtc
gatattattggtctgagcggtctcatcactccgtcccttgacgaaatgatgcatgttgcc
agcgaaatgcagcgcacgggtttctcggtcccgctaatgatcggtggcgccaccacttcc
aaggcgcacaccgcggtcaagatcgagcccaactatcaaaatgacctggtggtgtacgtg
ccggatgcatcccgaagtgtatcggtggcgtccctgttactgggtgagcaaaaggctgga
ttcgtcagcgagcgacgagaagaatacgtgcaggttcgagagcgtatcgctaaccgcaag
ccaaaggccaagcgcctgccctatgacaaagccctggccaaccgcgctgtatttgattgg
gagagctaccaaccacccacgccgagctttaccggtgtccgggtgtttaagaatattccc
ttacaggatctggtcgacactattgactggactcccttcttcatcacctgggagcttgcg
ggcaaataccccaagatactcgaggatgatgtagtcggtgaacaagccagagacctgttt
gcagacgcacaggccatgctcaagaaaattgttgaagaggactggctggaggcttgtgca
gtcgtcggcttctggcctgctcacagcgatggcgaagacgttctggtagataccggggac
gagactgctccgctacgcttgcatcatctgcgacaacaaaccgaaaaagccaacgatcaa
ccgaatctgagtctcagtgactatgtggccccggcaaatgattacatcggtggtttctgt
gttacgacgggtcacggtgtttcccagcgtgctgctgcctttgaagcgaaccatgatgac
tacaattcgatcatgctcaaggccttggccgatcgattggcagagtcactggctgaacat
atgcacctgcgtgttcgccaggaattctggggctatgcagcgaatgaacagctatcaaac
gaggatttgatcagggagcgctatcggggcatacgccctgctcctggttaccctgcctgt
cctgatcacaccgagaagcgagctttgttcaacttgctggacgctgaagagcgctgcggg
gtgacgctgtctgataactacgccatggagccggcatcgtcggtgagcggttggtacttc
tcacacccggatgcacgatactttgccgtagggaaaattggcgaagatcagcttgaatcg
atcgcgacgcgtaagggtgtgaagacggccgcactggctcgctggctggctcccaacctc
gactaa

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