KEGG   PATHWAY: cvf04136
Entry
cvf04136                    Pathway                                
Name
Autophagy - other - Charadrius vociferus (killdeer)
Description
Autophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either in a housekeeping capacity or during stress and senescence. The process of autophagy could be divided into several stages: induction, vesicle nucleation, elongation and closure, and fusion and digestion. Most essential autophagic machineries are conserved throughout eukaryotes (see map04140 for animals and map04138 for fungi). This map is for other eukaryotes including plants and protists, where autophagy related genes (ATGs) play similar roles in the life cycle. However, autophagy has been relatively less studied in lower eukaryotes.
Class
Cellular Processes; Transport and catabolism
Pathway map
cvf04136  Autophagy - other
cvf04136

Other DBs
GO: 0006914
Organism
Charadrius vociferus (killdeer) [GN:cvf]
Gene
104281571  PIK3R4; phosphoinositide 3-kinase regulatory subunit 4 [KO:K08333] [EC:2.7.11.1]
104283365  ATG2B; autophagy-related protein 2 homolog B [KO:K17906]
104283559  IGBP1; immunoglobulin-binding protein 1 [KO:K17606]
104284375  ULK2; serine/threonine-protein kinase ULK2 [KO:K08269] [EC:2.7.11.1]
104284796  ATG101; autophagy-related protein 101 [KO:K19730]
104285385  ATG9A; LOW QUALITY PROTEIN: autophagy-related protein 9A [KO:K17907]
104285512  ATG4C; cysteine protease ATG4C [KO:K08342] [EC:3.4.22.-]
104287141  PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [KO:K04382] [EC:3.1.3.16]
104287793  ATG16L1; autophagy-related protein 16-1 isoform X1 [KO:K17890]
104288079  RPTOR; regulatory-associated protein of mTOR isoform X1 [KO:K07204]
104288128  ATG10; ubiquitin-like-conjugating enzyme ATG10 [KO:K17888]
104290272  ATG4A; cysteine protease ATG4A [KO:K08342] [EC:3.4.22.-]
104290455  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
104290779  ATG7; ubiquitin-like modifier-activating enzyme ATG7 [KO:K08337]
104290892  WIPI2; WD repeat domain phosphoinositide-interacting protein 2 [KO:K17908]
104291621  PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform [KO:K04382] [EC:3.1.3.16]
104292209  BECN1; beclin-1 [KO:K08334]
104292260  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
104292290  ATG3; ubiquitin-like-conjugating enzyme ATG3 [KO:K08343]
104293581  ATG4B; cysteine protease ATG4B [KO:K08342] [EC:3.4.22.-]
104294260  ATG5; autophagy protein 5 [KO:K08339]
104294473  GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
104294543  GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1 [KO:K08341]
104295094  WIPI1; WD repeat domain phosphoinositide-interacting protein 1 [KO:K17908]
104295296  MLST8; target of rapamycin complex subunit LST8 [KO:K08266]
104295860  ATG13; autophagy-related protein 13 isoform X1 [KO:K08331]
Compound
C00350  Phosphatidylethanolamine
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
Reference
  Authors
Duszenko M, Ginger ML, Brennand A, Gualdron-Lopez M, Colombo MI, Coombs GH, Coppens I, Jayabalasingham B, Langsley G, de Castro SL, Menna-Barreto R, Mottram JC, Navarro M, Rigden DJ, Romano PS, Stoka V, Turk B, Michels PA
  Title
Autophagy in protists.
  Journal
Autophagy 7:127-58 (2011)
DOI:10.4161/auto.7.2.13310
Reference
  Authors
Avin-Wittenberg T, Honig A, Galili G
  Title
Variations on a theme: plant autophagy in comparison to yeast and mammals.
  Journal
Protoplasma 249:285-99 (2012)
DOI:10.1007/s00709-011-0296-z
Reference
  Authors
Liu Y, Bassham DC
  Title
Autophagy: pathways for self-eating in plant cells.
  Journal
Annu Rev Plant Biol 63:215-37 (2012)
DOI:10.1146/annurev-arplant-042811-105441
Reference
  Authors
Yoshimoto K
  Title
Beginning to understand autophagy, an intracellular self-degradation system in plants.
  Journal
Plant Cell Physiol 53:1355-65 (2012)
DOI:10.1093/pcp/pcs099
Reference
  Authors
Li F, Chung T, Vierstra RD
  Title
AUTOPHAGY-RELATED11 plays a critical role in general autophagy- and senescence-induced mitophagy in Arabidopsis.
  Journal
Plant Cell 26:788-807 (2014)
DOI:10.1105/tpc.113.120014
Reference
  Authors
Michaeli S, Galili G, Genschik P, Fernie AR, Avin-Wittenberg T
  Title
Autophagy in Plants--What's New on the Menu?
  Journal
Trends Plant Sci 21:134-44 (2016)
DOI:10.1016/j.tplants.2015.10.008
Reference
  Authors
Yang X, Bassham DC
  Title
New Insight into the Mechanism and Function of Autophagy in Plant Cells.
  Journal
Int Rev Cell Mol Biol 320:1-40 (2015)
DOI:10.1016/bs.ircmb.2015.07.005
KO pathway
ko04136   

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