Entry Name ABC transporters - Crocosphaera subtropica
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Other DBs Organism Crocosphaera subtropica [GN:
cyt ]
Gene cce_0302 cmpD; bicarbontate transport system ATP-binding protein [KO:K11953 ] [EC:7.3.2.-]
cce_0303 cmpC; bicarbontate transport system ATP-binding protein [KO:K11952 ] [EC:7.3.2.-]
cce_0304 cmpB; bicarbontate transport system permease protein [KO:K11951 ]
cce_0305 cmpA; bicarbontate transport system substrate-binding protein [KO:K11950 ]
cce_0399 natB; probable ABC transporter periplasmic branched chain amino acid binding protein [KO:K11954 ]
cce_0847 modA; molybdenum ABC transporter, periplasmic binding protein [KO:K02020 ]
cce_0884 pstA1; phosphate ABC transporter, permease protein [KO:K02038 ]
cce_0885 pstC1; phosphate ABC transporter, permease protein [KO:K02037 ]
cce_0886 pstS; phosphate ABC transporter, periplasmic phosphate-binding protein [KO:K02040 ]
cce_1164 pstC2; phosphate ABC transporter, permease protein [KO:K02037 ]
cce_1165 pstA2; phosphate ABC transporter, permease protein [KO:K02038 ]
cce_1242 mntC; Mn2+ ABC transporter, periplasmic binding protein [KO:K11601 ]
cce_1531 cbiQ3; putative cobalt ABC transporter permease protein [KO:K16785 ]
cce_2193 hlyB1; toxin secretion ABC transporter ATP-binding protein [KO:K11004 ]
cce_2558 phnD; phosphonate ABC transporter, phosphate-binding protein [KO:K02044 ]
cce_2559 phnE; phosphonate ABC transporter, permease protein [KO:K02042 ]
cce_2961 znuC; zinc ABC transporter, periplasmic binding protein [KO:K09815 ]
cce_3679 cbiQ2; putative cobalt ABC transporter permease protein [KO:K02008 ]
cce_4415 cbiQ1; putative cobalt ABC transporter permease protein [KO:K16785 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway
