Dermochelys coriacea (leatherback sea turtle): 119843575
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Entry
119843575 CDS
T09064
Name
(RefSeq) LOW QUALITY PROTEIN: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
dcc
Dermochelys coriacea (leatherback sea turtle)
Pathway
dcc00140
Steroid hormone biosynthesis
dcc01100
Metabolic pathways
Module
dcc_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
dcc_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
dcc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
dcc_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
dcc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
119843575
Enzymes [BR:
dcc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
119843575
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
119843575
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
NmrA
KR
Motif
Other DBs
NCBI-GeneID:
119843575
NCBI-ProteinID:
XP_038229001
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Position
1:209146114..209165915
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AA seq
376 aa
AA seq
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MSLAGVSCLVTGAGGFLGQRIVHLLLGGEKELAEIRTLDIAFSYEARRNFTNFKGQTVVK
ILEGDIRDATFLNSACEGVSLVIHTASIIDTLGLVEKQLLWEVNVTGTQLLLEACVRSNV
QHFIYTSTIEVIGPNCRGDPICNGDEDTAYQSTSGFPYAQSKRLAETSVLKANGQALKHG
GIFLTCSLRSMYIFGEGCQFLQSHLDKSLLNKNVYLRISRKDALVNPVYVGNVAWAHIQV
AKALRNPEKAKHIKGHFYYISDDTPHMSYADLNYELTKELGFGIEPHPPMPLMMLYYFAL
LLEVVSFLLRPFVKYIPSTNRHLVILLNTQFTFSYRKAWRDLAHAPLQWKEAKQRTSQWI
ASVIPQRRAYLKNKAA
NT seq
1131 nt
NT seq
+upstream
nt +downstream
nt
atgtctttggctggagtgagctgtctggtgacaggagcaggtggatttcttggccagaga
attgtgcacttactgctgggaggagagaaggagctggctgagatccgaaccctggacata
gcctttagctacgaggcacgcaggaattttacaaatttcaagggtcagactgtggtgaag
atcttggaaggggacatccgggatgctacattcttgaacagcgcttgcgagggtgtctcc
cttgtcatccatacagcatccatcattgacaccttgggccttgtagagaagcagctgctc
tgggaagtcaatgtaacaggtacccagctgctgctggaggcctgtgtccgcagtaatgtc
cagcacttcatctacactagtaccatagaagtgataggcccaaactgcagaggggacccc
atctgcaacggggatgaagatacagcctaccagagcacatcaggatttccttatgcccag
agtaagagactggcagagacgtctgttctgaaggcaaatggtcaggcactgaagcatggt
ggcatcttcctgacgtgttccttgaggtccatgtatatctttggagaaggatgccagttt
ctccagagtcacctggataaaagcctcttgaacaaaaatgtctacctgcggatttctagg
aaggacgctctggtgaatcctgtgtatgtgggaaacgttgcatgggctcacatccaggtg
gcaaaagccttgaggaacccggaaaaagccaagcacatcaaagggcacttctactacatc
tctgatgacactcctcacatgagctatgccgacctaaattatgagctgaccaaggagctg
gggtttgggattgagccccacccgcccatgccgctgatgatgctgtactactttgcgcta
ctgctagaagttgtgagcttcctacttaggccctttgtcaaatacatcccctccaccaac
cgtcaccttgtgatcttgctgaacacacagttcacattctcctacaggaaggcatggcgg
gatttggctcatgccccgctacaatggaaagaggccaagcagcgcaccagccagtggatt
gcctcagtgattccacaaaggagggcatacctgaaaaacaaggctgcctaa
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