Delphinus delphis (saddleback dolphin): 132413334
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Entry
132413334 CDS
T11117
Symbol
HSD11B1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
ddp Delphinus delphis (saddleback dolphin)
Pathway
ddp00140
Steroid hormone biosynthesis
ddp00980
Metabolism of xenobiotics by cytochrome P450
ddp01100
Metabolic pathways
ddp05204
Chemical carcinogenesis - DNA adducts
Module
ddp_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
ddp00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
132413334 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
132413334 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
132413334 (HSD11B1)
Enzymes [BR:
ddp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
132413334 (HSD11B1)
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Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
2-Hacid_dh_C
Pyr_redox_2
NAD_binding_2
Pyr_redox_3
Shikimate_DH
Methyltransf_25
Pyr_redox
Motif
Other DBs
NCBI-GeneID:
132413334
NCBI-ProteinID:
XP_059851350
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All DBs
Position
1:complement(146952447..146981969)
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AA seq
294 aa
AA seq
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MAFMKKYLLPILGIFLAYYYYSAKEEFRPEMLRGKRVIVTGASKGIGREMAYHLARMGAH
VVVTARSEEALKKVVSHCLELGASSAHYVAGTMENMTFAEQFVAKAGKLMGGLDMLILNH
ITNTNNPMTVFIDDIDHVRKSMEVNFLSYVVLSGAAMPMLKQSNGSIVVVSSIAGKTANP
LIAAYSASKFALDGFFSSIRVEYAVTNVNVSITLCILGLIDTETAMTGTAGIYNAEASPK
EECALEIIKGGALRQKEVYYDSSVLTPFLLGNPGRKIMEFLSLRNYNMEIFINN
NT seq
885 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaagaaatatctcctccccattctggggatcttcttggcctactactac
tattctgcgaaggaggagttcagaccagagatgcttcgaggaaaaagagtgattgtcaca
ggggccagcaaggggattggaagagagatggcctatcatctggcgagaatgggagcccat
gtggtagtgacagcgaggtcagaagaagctctaaagaaggtggtatcccactgcctggag
ctcggcgcatcctccgcgcactacgttgctggcaccatggagaacatgaccttcgcagag
caatttgtggccaaagctggaaaactcatggggggactagacatgctcattctcaaccac
atcaccaacaccaacaatcctatgactgtatttatcgatgacattgaccacgtgcgcaaa
agcatggaggtcaacttcctgagttatgtggtcctgagcggggccgccatgcccatgctg
aagcagagcaacgggagcattgtggttgtctcctcgatagccgggaaaacagctaatcca
cttattgctgcctattctgcaagcaagtttgctctggatgggttcttctcctctatcagg
gtggaatatgcagtgaccaatgtcaatgtgtcgatcaccctctgtatccttggcctcata
gacacagaaacagccatgacaggaactgctgggatatacaatgcagaagcatctccaaag
gaagaatgtgccctggagattatcaaagggggagctctgcgccaaaaggaagtatattat
gacagttcggtcttgactcctttcctgctgggaaatccagggaggaagatcatggaattt
ctctccttacgaaattataatatggaaatatttataaacaactag
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