Delphinus delphis (saddleback dolphin): 132413700
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Entry
132413700 CDS
T11117
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
ddp Delphinus delphis (saddleback dolphin)
Pathway
ddp04022
cGMP-PKG signaling pathway
ddp04068
FoxO signaling pathway
ddp04081
Hormone signaling
ddp04140
Autophagy - animal
ddp04152
AMPK signaling pathway
ddp04211
Longevity regulating pathway
ddp04213
Longevity regulating pathway - multiple species
ddp04910
Insulin signaling pathway
ddp04920
Adipocytokine signaling pathway
ddp04923
Regulation of lipolysis in adipocytes
ddp04930
Type II diabetes mellitus
ddp04931
Insulin resistance
ddp04932
Non-alcoholic fatty liver disease
ddp04935
Growth hormone synthesis, secretion and action
ddp05010
Alzheimer disease
ddp05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ddp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
132413700 (IRS2)
04022 cGMP-PKG signaling pathway
132413700 (IRS2)
04152 AMPK signaling pathway
132413700 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
132413700 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
132413700 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
132413700 (IRS2)
04923 Regulation of lipolysis in adipocytes
132413700 (IRS2)
04920 Adipocytokine signaling pathway
132413700 (IRS2)
04935 Growth hormone synthesis, secretion and action
132413700 (IRS2)
09149 Aging
04211 Longevity regulating pathway
132413700 (IRS2)
04213 Longevity regulating pathway - multiple species
132413700 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
132413700 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
132413700 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
132413700 (IRS2)
04932 Non-alcoholic fatty liver disease
132413700 (IRS2)
04931 Insulin resistance
132413700 (IRS2)
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Gene cluster
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Motif
Other DBs
NCBI-GeneID:
132413700
NCBI-ProteinID:
XP_059851817
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All DBs
Position
18:complement(75549447..75577588)
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AA seq
1349 aa
AA seq
DB search
MASPPMNGRPGPAGGDGPNLNLNHNNNNNNSGVRKCGYLRKQKHGHKRFFVLRGPGAGGD
EAAAAATAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIA
LYTKDEYFAVAAENEQEQEGWYRALTDLVSEGRASAGDAPPAANAAAAPSASCSASLPGA
LGGSAGAAVAAAADDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIG
FVKLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETI
LEAMKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSL
AATPPAAKCSSCRVRTASEGDGGVAAGAGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSG
GCGGRASKVTLAPAGGALQHSRSMSMPVAHSPPAAATSPGSLSSSSGHGSGSYPPPPGPH
PHMQHPLHPQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSLRSNTPESIAETPP
ARDGSGGELYGYMTMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQP
SSASLDEYTLMRATFSGSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTD
DGYMPMTPGVALAGGGGSCKSDDYMPMSPTSVSAPKQILQPRAAVAALPPTGAAGPTPAS
AASRAFPGSGGGYKTSSPAESSPEDSGYMRMWCGGSKLSVESAADGRLLPNGDYLNMSPG
DAGASGTPPDFFSAALHAGGGGEMLRGVPGYCYSSLPRSYKAAYTCNGDNDQYVLMSSPV
GRILEEERLESTAGPGSTQPAGSFAAGAGGGGGHPQPPHQAVPSPGRPGGSGSGRLEGFL
GQRCRATRPTRLSLEGLQTLPRMHEYPLPPEPKSPGEYINIDFGEAGARLSPPAPPLLAS
AASSSSLLSAGSPASSLGSGTPGTSGDSRQRSPLSDYMNLDFSSPKSPQPGGQAGDPVGS
LDALLSPEASTYPPLPPRPAAPSSALQTAPPPPPPGELYRLPPAPPSQGPGAASSPSSGA
GDSGDYTEMAFGVAATPPQPIAAPPKPDGARVSSPVSGLKRLSLMDQVSGVEAFLQASQP
PDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSG
EGGGGSVLGGGDEPPTSPRQLPPPQHPQARPWTPSQPGGLVGCPGGSGSPMRRETSAGFQ
NGLNYIAIDVRDEPGLSPSPQQPQQHPQTGDKSAWGRTRSLGGLIGAVGAGSTGGVCVGP
GPGALPSASTYASLDFLTHHLKEATVVKE
NT seq
4050 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgatgaacgggcgccccgggccggcgggtggcgacggccccaacctc
aacctcaaccacaacaacaacaacaacaacagcggcgtgcgcaagtgcggctacctgcgc
aagcagaagcacggccacaagcgcttcttcgtgctgcgcggacccggagcgggcggcgac
gaggcggcggcggcggcgacagcgggcggggggccggcgccgcagccgccgcggctcgag
tactacgagagcgagaagaagtggcggagcaaagcgggcgccccgaagcgggtcatcgcg
ctcgactgctgcctgaacatcaacaagcgcgccgacgccaagcacaagtacctgatcgcc
ctctacaccaaggacgagtacttcgcagtggcggccgagaacgagcaggagcaggagggc
tggtaccgcgcgctcaccgacctggtcagcgagggccgagcgagcgccggcgacgcgccc
cccgccgccaacgccgccgccgccccctccgcgtcctgcagcgcctccctgcccggcgcc
ctgggcggctcggccggcgccgccgtcgccgccgcggccgatgacagctacgggctggtg
gcgcccgccacggccgcctaccgtgaggtgtggcaggtgaacctgaagcccaaaggcctg
ggccagagcaagaacctgacgggcgtgtaccgcctgtgcctgtcggcgcgcaccatcggc
ttcgtgaagctcaactgcgagcagccgtcggtgacgctgcagctgatgaacatccgccgc
tgcggccactcggacagcttcttcttcatcgaggtgggccgctcggccgtgacgggcccc
ggtgagctgtggatgcaggcagacgactcggtggtggcgcagaacatccacgagaccatc
ctggaggccatgaaggcgctcaaggagctcttcgagttccggccgcgcagcaagagccag
tcgtccggctcgtcggccacgcaccccatcagcgtccccggcgcgcgtcgccaccaccac
ctggtcaacctgccccccagccagacgggcctggtgcgccgctcgcgcaccgacagcttg
gccgccacaccgccggccgccaagtgcagctcgtgccgggtgcgcacggccagcgagggc
gacggcggcgtggcggcgggggccggggcggcgggcggcaggccggtgtcggtggcgggg
agccccctgagcccggggccggtgcgcgcgcccctgagccgctcgcacaccctgagcggc
ggctgcggcggccgcgcgagcaaggtgacgctggcgccggcagggggcgccctgcagcac
agccgctccatgtccatgcccgtggcgcactcgcccccggcggccgccaccagccccggc
agcctgtcgtccagcagcgggcacggctcgggctcctacccgccgcccccgggcccgcac
ccgcacatgcagcaccccctgcacccccagcgaccctccagcggcagcgcctcggcctcg
ggctcccccagcgatcctggcttcatgtccctggacgagtacggctcgagccctggggac
ctgagagccttctgcagtctcaggagcaacacgcccgagtccatcgccgagacgcccccg
gccagggacggcagcgggggcgagctgtacgggtacatgaccatggaccggcccctgagc
cactgcggccgaccctaccgcagagtctccggggacggggcccaggacttggacaggggg
ctgaggaagaggacctactccctgaccacgcctgcccggcagcggccagtgccccagccc
tcctccgcgtccctggatgaatacaccctgatgcgggccaccttctccggcagctcaggc
cgcctctgcccgtcgtgccccgcgtcctcccccaaagtggcctaccacccctaccccgag
gactacggcgacatcgagatcgggtcgcacaggagctccagcagtaacctgggcacggac
gacggctacatgcccatgacccccggcgtggccctcgcgggcggcggcgggagctgcaag
agcgacgactacatgcccatgagccccaccagcgtgtccgccccgaagcagatcctgcag
ccgcgcgccgccgtcgcggccttgccccccacgggagccgcggggcccacgcccgcgtct
gccgccagcagggccttcccggggagcgggggcggctacaagaccagctccccggccgag
agctccccggaggacagcgggtacatgcgcatgtggtgcggaggctccaagctgtccgtg
gagagcgccgccgacggcaggctgcttccaaacggggactacctcaacatgtcccccggc
gacgcgggagcctcgggcaccccgcccgacttcttctcggccgccctgcacgccggcggc
ggcggggagatgctccggggcgtccccggctactgctacagctccctgccgcgctcttac
aaggccgcctacacctgcaacggggacaacgaccagtacgtgctcatgagctcccccgtg
gggcgcatcctggaggaggagcggctggagtcgacggccggcccggggtccacgcagcca
gccggctccttcgcggccggggcagggggcggcggcggccacccgcagccaccccaccag
gcggtgccttcgcccgggaggcccggtggcagcggcagcggccgcctggagggcttcctg
ggccagcgctgccgggccacgcggcccacgcgcctgtccctggaggggctgcagaccctg
ccccgcatgcacgagtatcccctgccgcccgagcccaagagcccgggcgagtacatcaac
atcgacttcggcgaggcgggcgcgcgcctgtcgccgcccgctcccccgctgctggcctcg
gccgcctcgtcgtcgtcgctgctgtccgccggcagcccggcctcatcgctgggttcgggc
accccgggcacgagcggcgacagccggcagcgctccccgctctccgactacatgaacctc
gacttcagctcgcccaagtcaccccagccgggcggccaggccggggaccccgtgggctct
ctggacgccctcctgtcccccgaggcctccacgtacccgccgctgcccccgcgccccgcc
gccccctcctcggccctgcagacggcgcccccgccgcccccgcccggagagctgtaccgc
ctgcctccggcaccaccctcccagggccctggcgcggcctcctctccatcctcgggggcg
ggcgacagcggcgactacaccgagatggccttcggcgtggctgccacgccgccgcaaccg
atcgccgcgcccccgaagcccgacggggcccgcgtgagcagccccgtgtccggcctgaag
aggctaagcctcatggaccaggtgtcgggggtcgaggccttcctgcaagccagccagccc
ccagacccgcaccgcggggccaaggtcatccgtgcggacccgcaagggggccgccgccgc
cacagctcggagaccttctcctcgaccaccactgtgacccccgtgtccccgtccttcgcc
cacaaccccaagcgccacaactcggcctcggtggagaacgtgtctctcaggaaaagcggc
gaagggggcggcggcagcgttctgggtggcggtgacgagccccccacgtccccccgccag
ttgccaccgccgcaacacccgcaggcgcggccctggacgccgagccagcccgggggcttg
gtcggctgccccgggggcagtggctcgccgatgcgccgggagacttccgctggcttccag
aacggcctcaactacatcgccatcgacgtgagggacgagccggggctgtcgccgtccccg
cagcagcctcagcagcatcctcagacgggagacaagagcgcctggggccggacccggagc
ctcgggggcctcatcggcgcggtaggggccggcagcaccggcggggtgtgtgtggggccc
ggccctggcgccctgccctccgccagcacctacgccagcctcgacttcttgacgcatcac
ctgaaagaggccacggtcgtgaaagagtga
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