KEGG   Desulfoluna limicola: DSLASN_09590
Entry
DSLASN_09590      CDS       T07859                                 
Name
(GenBank) trimethoprim-resistant dihydrofolate reductase DfrA1
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
dek  Desulfoluna limicola
Pathway
dek00670  One carbon pool by folate
dek00790  Folate biosynthesis
dek01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:dek00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    DSLASN_09590
   00670 One carbon pool by folate
    DSLASN_09590
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:dek01504]
    DSLASN_09590
Enzymes [BR:dek01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     DSLASN_09590
Antimicrobial resistance genes [BR:dek01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    DSLASN_09590
SSDB
Motif
Pfam: DHFR_1 KGG
Other DBs
NCBI-ProteinID: BCS95327
UniProt: A0ABN6F1J7
LinkDB
Position
1141893..1142366
AA seq 157 aa
MKLSFVVAVAENGVIGDGADIPWVIPGELSLFKAVTYHHSLLMGRKTWEAIGRPLPGREM
IVLTRNASYKAEGCRVCTTLEEALEIGSKGGRRIMVAGGGEIFRLTLPLADTLHISHIHT
DVPGDVIMPETPAEFKPVFSQYYPADIPYTYTIYQKR
NT seq 474 nt   +upstreamnt  +downstreamnt
atgaagctttcgtttgtagtggcagttgcagagaacggggtgattggcgatggggcagat
attccgtgggttattccaggggagctgtccctgttcaaggcggtgacttaccaccacagc
ttgctgatgggccgaaagacctgggaggccattggaaggcccctgccggggcgggaaatg
attgttctcacccgcaacgcctcatacaaagccgagggatgccgggtctgtaccaccctt
gaagaggcccttgagattgggagcaaaggggggcgacggatcatggtggccggaggtggt
gaaattttcaggctgacccttcccctggccgacacccttcatatctcccacattcacacg
gacgttcccggtgacgtcatcatgccggagacccctgccgagtttaagccggtcttttcc
cagtactacccagccgacattccctacacgtacaccatttaccagaaacgttga

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