Devosia sp. MC521: H4N61_07980
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Entry
H4N61_07980 CDS
T08408
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
devo
Devosia sp. MC521
Pathway
devo00270
Cysteine and methionine metabolism
devo00450
Selenocompound metabolism
devo00670
One carbon pool by folate
devo01100
Metabolic pathways
devo01110
Biosynthesis of secondary metabolites
devo01230
Biosynthesis of amino acids
devo04980
Cobalamin transport and metabolism
devo04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
devo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
H4N61_07980 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
H4N61_07980 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
H4N61_07980 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
H4N61_07980 (metH)
04980 Cobalamin transport and metabolism
H4N61_07980 (metH)
Enzymes [BR:
devo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
H4N61_07980 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
QMW64226
UniProt:
A0A7G5LQA4
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Position
complement(1663603..1667346)
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AA seq
1247 aa
AA seq
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MSPSELNISSPVSQDWNEVRSALSKAMEERILVLDGAMGTMIQRLGLTEENFRGERFKDW
SHPLKGNNDLLVITEPKMIEDIHYNYYMAGADIVETNTFSGTSVAQADYACESAVYDINY
QGVIVARRAARRAEAEDGRRRYVAGALGPTTKTSSMSTDVNNPGHRSISFDELAIAYEEA
LRGLIDAGADLLLFETITDTLNTKAGLFAARKIFDERGIDVPIMISGTITDRSGRTLSGQ
TPTAFWYSIRHANPITIGLNCALGADLMRDHIAELSKVADTFICAYPNAGLPNEMGAYDE
TPDDMARQLQSFASEGLLNIVGGCCGSTPDHIRAIAQMVAQYEPRKVPEIERLLRLAGLE
PFTLTADIPFVNVGERTNVTGSAKFKKLITAGDYTTALDVARDQVANGAQVIDINMDEGL
IDSKQVMVDYLNLLAAEPDIAKVPLMIDSSKWDVIEAGLKCVQGKALVNSISLKEGEDAF
IHHAKLVRAYGAAVVVMAFDESGQADTKQRKVEICTRAYKILTEQVGFPPEDIIFDPNVF
AVATGIEEHNNYGVDFIEATKEIVETLPHVHISGGISNLSFSFRGNEPVREAMHAVFLYH
AIKVGMDMGIVNAGQLAVYETIDAELRDACEDVILNRTPNATDRMLELAERYRGQGGAAG
KAKDLSWRELPVGQRITHALVNGVTEFIEADTEEARLAYDRPLHVIEGPLMDGMNVVGDL
FGSGKMFLPQVVKSARVMKQAVAYLLPYMEEEKAANGGTGRSSAGKVLMATVKGDVHDIG
KNIVGVVLACNNYEIIDLGVMVPSAKILEVAKAENVDIIGLSGLITPSLDEMVHVAAEME
REGFNIPLLIGGATTSRVHTAVKIHPRYNRGQAVYVNDASRAVGVVSALLSDDQNAAFVE
TTRAEYAKAAAAHERAELDKKRLPLATARANAFKSNFDGYTPPKPTFLGTKTITDLDLGE
IARYIDWTPFFQSWELKGRYPAILEDEKQGEAARALWADAQKMLKQIIGEKWFNLKAVIG
FWPANRVEDDIRLFTGEDRATELNTFFTLRQQLSKRTDSANVALSDFVAPVGTPDYLGGF
VVTAGLEEVAIAERFEKANDDYSSILVKALADRYAEALAEYMHERVRKEHWGFGKDETFA
PDELVGEPYAGIRPAPGYPAQPDHTEKTTLFNLLDAEAQVGVTLTESYAMWPGSSVSGLY
FSHPDAYYFGVAKVERDQVLDYAERKGMAVAEVERWLGPVLNYIPGK
NT seq
3744 nt
NT seq
+upstream
nt +downstream
nt
atgagcccctccgagctgaacatctcaagcccagtttcccaggattggaacgaagtgcgc
tccgcactttcaaaggctatggaggagcgtatcctcgttctcgacggcgctatggggacg
atgatccagcgtctcggcctgacggaggaaaacttccgcggcgagcgcttcaaggattgg
tcgcacccactcaagggcaataacgacctcctcgtcatcaccgaaccgaaaatgatcgag
gacatccactacaactattatatggcgggtgcggatatcgttgaaaccaacacgttttct
ggcacctctgtggcgcaggccgactatgcctgcgaaagcgctgtctacgacatcaactac
caaggcgtgatcgttgcccgccgcgctgcacggcgcgctgaggcagaagatggtcgtcgc
cgttatgttgcgggcgccctcggaccgaccacaaaaacctcctccatgtcgaccgacgtc
aacaatcccggtcaccgctccatcagcttcgacgagctggcaatcgcctatgaagaagcc
ctgcgcggcctgatcgacgctggcgctgaccttctgctctttgaaaccatcaccgacacg
ctcaacaccaaggccggcctgttcgctgctcgcaagatttttgacgagcgcggcatcgat
gtgccgatcatgatttcgggcaccatcaccgatcgttcgggccgcacgctctcgggccag
accccgaccgccttctggtactcgatccgccacgccaacccgatcaccatcgggctgaac
tgcgcgctcggcgccgatctgatgcgcgatcacatcgccgaactctccaaggtcgccgat
acctttatctgcgcctatccgaacgctggcctgcccaatgaaatgggtgcttacgacgaa
acgccggacgacatggcgcgtcagttgcaaagctttgcctccgaaggcctcctcaatatc
gtcggcggctgctgcggctcgaccccagaccatatccgcgccatcgcccagatggtcgcg
cagtatgagccacgcaaagttcccgagatcgagcgcctgctgcgtctcgcgggcctagag
ccgttcacgctcaccgcggacattcctttcgtcaacgttggcgagcgcaccaatgtcacc
ggctcggccaagttcaaaaaactgatcaccgctggcgactacaccacagcgctcgacgtt
gcgcgggaccaagtcgcgaatggcgctcaggtcatcgacatcaatatggacgagggcctg
atcgatagtaagcaggtcatggttgactacctcaacctgctcgccgccgaacccgatatc
gccaaggttccgctgatgatcgacagctccaagtgggatgtcatcgaagctggtctgaaa
tgcgttcagggcaaggcgctggtcaactcgatctcgctcaaggaaggcgaagacgccttc
attcatcacgccaagctcgttcgcgcctatggcgctgcggttgtggtgatggcctttgac
gaaagcggtcaggccgataccaagcagcgtaaggtcgaaatctgtacccgtgcgtataag
atcctcaccgagcaggtcggcttcccgccagaagacatcatcttcgacccgaacgtgttc
gcggttgcgaccggtattgaagaacataacaattacggcgtcgacttcatcgaagcgacc
aaggagattgttgagaccctgccccatgttcacatctcgggcggtatttccaacctctcc
ttctcgttccgcggcaatgagccggtgcgtgaagccatgcacgcggtcttcctctaccat
gccatcaaggtcggcatggacatgggcatcgtcaacgccggtcagctggcggtttacgaa
accatcgacgccgaactgcgcgatgcctgcgaggacgtgatcctcaaccgcacgccaaat
gccacggatcgtatgctcgagctggcggaacgctatcgcggtcagggcggcgcagcgggc
aaggccaaggacctctcttggcgcgaactccccgtcggtcagcgcattacccatgcgctg
gtcaatggcgtcaccgaattcatcgaggcagacaccgaagaagcccgcctcgcttatgac
cgcccgctgcacgtcatcgaaggcccgctgatggacggcatgaatgtcgtcggcgacctc
ttcggctcgggcaagatgttcctgccgcaggtggtaaagtccgcccgcgtcatgaagcag
gccgttgcctatctcctgccctatatggaagaggaaaaggctgccaatggcggcactggc
cgctccagcgcgggcaaggttctgatggcaaccgtgaagggcgacgtccacgacatcggc
aaaaacatcgtcggcgtggttctggcttgcaacaactacgaaatcatcgacctcggcgtt
atggtcccgtcggcgaagattttggaagtggccaaggccgagaacgtcgacatcattggc
ctttcgggtctcatcaccccctcgctggacgaaatggtccatgtcgccgccgaaatggag
cgcgaaggatttaacatcccgctgctgattggtggggctacgaccagccgcgttcacacg
gcggtaaagatccacccgcgctacaaccgtggtcaggccgtttacgtcaacgacgccagc
cgcgctgtgggtgttgtctctgcgctcctctcggacgatcagaacgccgcattcgtcgaa
accacacgcgcggaatacgccaaggcggcggctgcgcacgaacgtgctgaactggacaaa
aagcgcctgccgctggccactgcccgcgccaatgcgttcaagtccaactttgatggctac
acgccaccaaagccgactttcctcggcaccaagaccatcaccgatctcgacctgggcgaa
atcgcccgctacatcgattggaccccgttcttccagagctgggaactcaagggccgctac
ccggccatccttgaagacgagaaacagggcgaagccgctcgtgcgctctgggctgacgct
cagaaaatgctcaagcagatcattggcgaaaaatggttcaacctgaaggccgtcatcggc
ttctggcccgcaaaccgcgtcgaggacgacatccgtctctttaccggcgaagatcgcgcc
actgagctgaataccttcttcaccctgcgccagcagctgtccaagcgcaccgatagcgcc
aatgtcgccctgtccgacttcgtcgctcccgtcggcacgcccgactatcttggtggtttt
gttgtcaccgcaggccttgaagaagtcgccattgcagagcgcttcgaaaaggcgaatgac
gattattcgtccattctcgttaaggccctcgcggaccgttatgccgaagccctagccgaa
tatatgcacgagcgcgtccgtaaggagcactggggctttggcaaggacgagacgtttgcg
ccagacgagttggttggcgaaccctatgccggcattcgcccggctccgggctacccagct
cagccagaccacactgaaaagaccactcttttcaatctactagatgcagaagctcaagtc
ggagttacactcactgagagctatgccatgtggccaggctcgtccgtttccggtctctat
ttcagccatcctgacgcctattattttggcgtcgccaaggtcgaacgcgatcaggttctg
gactatgcggaacgcaagggcatggcggttgccgaagtggaacgttggctcggccctgtg
ctgaactacattccgggtaagtaa
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