Delphinapterus leucas (beluga whale): 111169081 Help Entry 111169081         CDS       T05885                                  Symbol HK2 Name (RefSeq) hexokinase-2   KO K00844   hexokinase [EC:2.7.1.1] Organism dle  Delphinapterus leucas (beluga whale) Pathway dle00010   Glycolysis / Gluconeogenesis dle00051   Fructose and mannose metabolism dle00052   Galactose metabolism dle00500   Starch and sucrose metabolism dle00520   Amino sugar and nucleotide sugar metabolism dle00524   Neomycin, kanamycin and gentamicin biosynthesis dle01100   Metabolic pathways dle01200   Carbon metabolism dle01250   Biosynthesis of nucleotide sugars dle04066   HIF-1 signaling pathway dle04910   Insulin signaling pathway dle04930   Type II diabetes mellitus dle04973   Carbohydrate digestion and absorption dle05230   Central carbon metabolism in cancer Module dle_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate dle_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc dle_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:dle00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     111169081 (HK2)    00051 Fructose and mannose metabolism     111169081 (HK2)    00052 Galactose metabolism     111169081 (HK2)    00500 Starch and sucrose metabolism     111169081 (HK2)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     111169081 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     111169081 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     111169081 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     111169081 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     111169081 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     111169081 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     111169081 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:dle04131]     111169081 (HK2) Enzymes [BR:dle01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      111169081 (HK2) Membrane trafficking [BR:dle04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     111169081 (HK2) SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  111169081 NCBI-ProteinID:  XP_022418736 UniProt:  A0A2Y9MCK5 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEIAKRFRKEMEKGLGAATHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMESQIYAIPEDIMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCLQTKLDESFLVSWTKGFKSSGV EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGVLDDIRTEFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFGGKLSPELLATGHFETKDVSDIEGEKDGIRKAREILVRLG LDPTQEDCVATHRVCQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKH PHFAKRLHKTVRRLVPDCDIRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLS REQLLEVKRRMKVEMERGLSKETHTIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPREVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGYKASGCEGEDVVTLLKEAIHRREEFDLEVVAVVNDTVG TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD FRTEFDAAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKHGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgcctcgcatctgctcgcctacttctttacggagctcaaccatgaccaagtgcag aaggttgaccagtatctctaccacatgcgtctttctgatgagaccctcctggagattgct aagcggttccgcaaggagatggagaaagggcttggagctgccacccaccccactgcttca gtaaaaatgctgcctacctttgtgaggtctactccagatgggacagaacatggagaattc ctggctctggaccttggagggaccaacttccgtgtgctttgggtgaaagtaacagacaat gggctccagaaggttgagatggagagccagatctacgccattcccgaggacatcatgcga ggcagtggcacccagctgtttgaccacattgctgaatgcctggccaacttcatggataag ctacaaatcaaagacaagaagctccctttgggttttaccttctcattcccctgtctccaa acaaaactagacgagagtttcctggtctcatggaccaaggggttcaagtccagtggtgtg gaagggaaagatgtggttactctgatccggaaagccatccagaggagaggggactttgat attgacattgtggcagtggtgaatgacacagttgggaccatgatgacctgtggttatgat gaccagaactgcgagattggtctcattgtgggcacgggcagcaacgcttgctacatggaa gagatgcgccacatcgacatggtggagggcgacgagggccgtatgtgtatcaacatggag tggggagccttcggggatgatggcgtgcttgatgacatccgcacggagtttgaccaggag atcgacatgggctctctgaaccccgggaagcaattatttgagaagatgatcagtggaatg tacatgggggagctcgtgaggcttatcctagtgaagatggccaaggaggagctgcttttt ggggggaagctcagccctgaactcctcgccacgggccactttgagaccaaagatgtttca gatatcgaaggggagaaggatggcatccggaaggcccgcgagatcctggtgcggctgggc ctggacccgacacaggaggactgtgtggccactcaccgggtctgccagatcgtgtccaca cgctcagccagcctgtgcgcggctacgctggcagccgtcctgcggcgcatcaaggagaac aagggcgaggagcggctgcgctccaccatcggggtggacggttctgtctacaagaagcat ccccatttcgccaagcgtcttcacaagaccgtgcggcgcctggtgcccgactgcgacatc cggttcctccgctctgaggacggcagtggcaagggggcagccatggtgacagcagtggcc taccggctggccgatcaacaccgagcccgccagaagaccctggagtctctgaagctgagc cgtgagcagctgctggaggtcaagaggaggatgaaggtagaaatggagcgaggtctgagc aaggagactcacaccattgcccccgtcaagatgctgcccacctatgtgtgtgccacccct gatggcacagagaaaggtgacttcctggccttggaccttgggggtaccaatttccgggtc ctgctggtgcgcgtgcggaatgggaagcgacgtggagtggagatgcacaacaagatctac tctatcccgcgggaggtcatgcacggcacaggggatgagctctttgaccacatcgtccag tgcattgccgacttccttgagtacatgggcatgaagggcgtgtccctgcctctgggtttc accttctccttcccctgccagcagaacagcctggacgagagcatcctcctcaagtggact aaaggctacaaggcatctggctgcgagggtgaggacgtggttacactgctgaaggaagcc atccaccggcgagaggagtttgacctggaggtagttgctgtggtgaatgacacagttggg actatgatgacctgtggctatgaagacccccactgtgaagttggcctcattgttggcacg ggcagcaatgcctgctacatggaggagatgcggaatgttgagctggtggaaggggaggag gggcggatgtgtgtcaacatggagtggggggcctttggggacaatggatgcctagatgac ttccgcacagaatttgatgcagctgtggatgaactttccctcaaccccggcaaacagagg ttcgagaagatgatcagtggcatgtacttgggcgaaattgttcgtaacatcctcatcgat ttcaccaaacatgggctgctcttccgtggccgcatctcggagcggctcaagacacgggga atctttgaaaccaagttcctgtctcagattgagagtgactgcctggccctgctgcaggtc cgtgccatcctgcaccacttagggctcgagagcacctgtgatgacagcatcattgtcaag gaggtgtgcactgtggtggcgcggcgggcagcccagctctgtggtgcaggcatggccgcc gtggtggacaaaatacgagagaaccgtgggctggacaccctcaaagtgacagtgggcgtg gacgggaccctctacaagctacatcctcactttgccaaagtcatgcacgagacggtgaag gacttggctccaaaatgtgatgtgtccttcctggagtcggaggatggcagtgggaagggg gcggctctcatcactgctgtggcctgccgcatccgagaggctggacagcggtag

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