Delphinapterus leucas (beluga whale): 111175513 Help Entry 111175513         CDS       T05885                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism dle  Delphinapterus leucas (beluga whale) Pathway dle04064   NF-kappa B signaling pathway dle04380   Osteoclast differentiation dle04650   Natural killer cell mediated cytotoxicity dle04658   Th1 and Th2 cell differentiation dle04659   Th17 cell differentiation dle04660   T cell receptor signaling pathway dle05135   Yersinia infection dle05166   Human T-cell leukemia virus 1 infection dle05235   PD-L1 expression and PD-1 checkpoint pathway in cancer dle05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:dle00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     111175513 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     111175513 (LCK)    04660 T cell receptor signaling pathway     111175513 (LCK)    04658 Th1 and Th2 cell differentiation     111175513 (LCK)    04659 Th17 cell differentiation     111175513 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     111175513 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     111175513 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     111175513 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     111175513 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     111175513 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dle01001]     111175513 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:dle03036]     111175513 (LCK) Enzymes [BR:dle01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      111175513 (LCK) Protein kinases [BR:dle01001]  Non-receptor tyrosine kinases   SRC family    111175513 (LCK) Chromosome and associated proteins [BR:dle03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     111175513 (LCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 SH3_16 SH3_3 Kdo Haspin_kinase DUF7063 Motif Other DBs NCBI-GeneID:  111175513 NCBI-ProteinID:  XP_022430797 UniProt:  A0A2Y9NNB7 LinkDB All DBs Position Unknown AA seq 509 aa AA seqDB search MGCSCSSNPEDDWMENIDVCENCHYPIVPLEGKAMLSTWNGSEVRDPLVTYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSVTTGQEGYIPFNFVARAN SLEPEPWFFKTLTRKDAERQLLAPGNTHGSFLIRESESTTGSFSLSVRDFDQTQGEVVKH YKIRNLDKGGFYISPRITFPGLHELVRHYMNSSDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTSTGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSGALSCKIADFGLARLIEDDEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLEQGYRMVRPDNCPDELYQLMMLCWKEL PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtgtgt gagaactgccattaccccatagttccactggagggcaaggccatgctgtccacctggaat ggctctgaagtgcgggatccactggtcacctacgagggctccaaccccccagcttctcca ctgcaagacaacctggttatcgccctgcacagctatgagccttcccacgatggagatctg ggcttcgagaagggtgaacagctacgtatcctggagcagaacggcgagtggtggaaggcg cagtccgtgaccacgggccaggaaggttacatccccttcaactttgtggccagagcgaac agcctggagcccgaaccctggttcttcaagaccctgacccgcaaggacgcggagaggcag ctcctggcgcccgggaacacgcacggctccttcctgatccgagagagtgaaagcaccacg ggatcgttttccctgtccgtccgggacttcgaccagacccagggagaagtggtgaaacat tacaagatccgtaacctggacaaaggcggcttctacatctccccccgcatcacttttcct ggcttgcatgagctggtccgccattacatgaattcttcggacgggctgtgcacgaggttg agccgcccctgccagacccagaagccccagaagccctggtgggaggatgagtgggaggtt cccagggagacgctgaagctggtggagaggctgggggctggccagttcggagaggtgtgg atggggtactacaacgggcacacgaaggtggcagtgaaaagcctgaagcagggcagcatg tctcccgatgccttcctggccgaggccaacctcatgaagcagctgcaacaccagcggctg gtccggctctacgcggtggtcacccaggagcccatctacatcatcacggaatacatggag aatgggagcctggtggattttctcaagacctccacaggcatcaagctgaccatcaacaaa ctcttggacatggcagcccaaattgcagagggcatggcgttcattgaagagcggaattat atccaccgtgacttgagggccgccaacatcctggtgtctggtgccctgagctgcaagatc gcagactttggcctagcgcgcctcattgaggacgatgagtacacagccagggagggggcc aagtttcccattaagtggacagcaccagaagccattaactatgggacgttcaccatcaag tcggacgtgtggtctttcgggatcctgctgacggagattgtcactcatggccgcatccct tacccaggcatgaccaatcctgaggtgattcagaacctggagcaaggctaccgcatggta cgacctgacaactgtccagatgagttgtaccaacttatgatgctgtgctggaaggagctc ccggaggaccggcccacctttgactacctgcgcagcgtgctggaggacttcttcacagcc acagagggccagtaccagccgcagccctga

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