Delphinapterus leucas (beluga whale): 111176387 Help Entry 111176387         CDS       T05885                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism dle  Delphinapterus leucas (beluga whale) Pathway dle04022   cGMP-PKG signaling pathway dle04068   FoxO signaling pathway dle04081   Hormone signaling dle04140   Autophagy - animal dle04152   AMPK signaling pathway dle04211   Longevity regulating pathway dle04213   Longevity regulating pathway - multiple species dle04910   Insulin signaling pathway dle04920   Adipocytokine signaling pathway dle04923   Regulation of lipolysis in adipocytes dle04930   Type II diabetes mellitus dle04931   Insulin resistance dle04932   Non-alcoholic fatty liver disease dle04935   Growth hormone synthesis, secretion and action dle05010   Alzheimer disease dle05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:dle00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     111176387 (IRS2)    04022 cGMP-PKG signaling pathway     111176387 (IRS2)    04152 AMPK signaling pathway     111176387 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     111176387 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     111176387 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     111176387 (IRS2)    04923 Regulation of lipolysis in adipocytes     111176387 (IRS2)    04920 Adipocytokine signaling pathway     111176387 (IRS2)    04935 Growth hormone synthesis, secretion and action     111176387 (IRS2)   09149 Aging    04211 Longevity regulating pathway     111176387 (IRS2)    04213 Longevity regulating pathway - multiple species     111176387 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     111176387 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     111176387 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     111176387 (IRS2)    04932 Non-alcoholic fatty liver disease     111176387 (IRS2)    04931 Insulin resistance     111176387 (IRS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  111176387 NCBI-ProteinID:  XP_022432484 UniProt:  A0A2Y9NC55 LinkDB All DBs Position Unknown AA seq 1347 aa AA seqDB search MASPPMNGRPGPAGGDGPNLNLNHNNNNNNSGVRKCGYLRKQKHGHKRFFVLRGPGAGGD EAAAAATAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIA LYTKDEYFAVAAENEQEQEGWYRALTDLVSEGRAIAGDAPPAAAAAPSASCSASLPGALG GSAGAAVAAAADDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFV KLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILE AMKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAA TPPAAKCNSCRVRTASEGDGGVAAGAGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGC GGRASKVTLAPAGGALQHSRSMSMPVAHSPPAAATSPGSLSSSSGHGSGSYPPPPGPHPH MQHPLHPQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSLRSNTPESIAETPPAR DGSGGELYGYMTMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSS ASLDEYTLMRATFSGSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDG YMPMTPGVALAGGGGSCKSDDYMPMSPTSVSAPKQILQPRAAVAALPPTGAAGPTPASAA SRAFPGSGGGYKTNSPAESSPEDSGYMRMWCGGSKLSVESAADGRLLPNGDYLNMSPGDA GASGTPPDFFSAVLHAGGGGGGGEMLRGVPGYCYSSLPRSYKAAYTCNGDNDQYVLMSSP VGRILEEERLESTASPGSTQPAGAFAAGAGGGGGHPQPPHPAVPSPGRPGGSGSGRLEGF LGQRCRATRPTRLSLEGLQTLTRMHEYPLPPEPKSPGEYINIDFGEAGARLSPPAPPLLA SAASSSSLLSAGSPASSLGSGTPGTSGDSRQRSPLSDYMNLDFSSPKSPQPGGQAGDPVG SLDALLSPEASAYPPLPPRPAAPSSALQPAPPPPPPGELYRLPPAPASQGPGAASSPSSG AGDSGDYTEMAFGVAATPPQPIAAPPKPDGARVSSPVSGLKRLSLMDQVSGVEAFLQASQ PPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKS GEGGGGSVLGGGDEPPTSPRQLPPPLHPQARPWTPSQPGGLVGCPGGSGSPMRRETSAGF QNGLNYIAIDVRDEPGLSPSPQQHPQTGDKSAWGRTRSLGGLIGAVGAGSTGGVCVGPGP GALPSASTYASLDFLTHHLKEATVVKE NT seq 4044 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgatgaacgggcgccccgggccggcgggtggcgacggccccaacctc aacctcaaccacaacaacaacaacaacaacagcggcgtgcgcaagtgcggctacctgcgc aagcagaagcacggccacaagcgctttttcgtgctgcgcggacccggagcgggcggcgac gaggcggcggcggcggcgacagcgggcggggggccggcgccgcagccgccgcggctcgag tactacgagagcgagaagaagtggcggagcaaagcgggcgccccgaagcgggtcatcgcg ctcgactgctgcctgaacatcaacaagcgcgccgacgccaagcacaagtacctgatcgcc ctctacaccaaggacgagtacttcgcagtggcggccgagaacgagcaggagcaggagggc tggtaccgcgcgctcaccgacctggtcagcgagggccgagcgatcgccggcgacgcgccc cccgccgccgccgccgccccctccgcgtcctgcagcgcctccctgcccggcgccctgggc ggctcggccggcgccgccgtcgccgccgcggccgatgacagctacgggctggtggcgccc gccacggccgcctaccgtgaggtgtggcaggtgaacctgaagcccaaaggcctgggccag agcaagaacctgacgggcgtgtaccgcctgtgcttgtcggcgcgcaccatcggcttcgtg aagctcaactgcgagcagccgtcggtgacgctgcagctgatgaacatccgccgctgcggc cactcggacagcttcttcttcatcgaggtgggccgctcggccgtcacgggccccggtgag ctgtggatgcaggcagacgactcggtggtggcgcagaacatccacgagaccatcctggag gccatgaaggcgctcaaggagctcttcgagttccggccgcgcagcaagagccagtcgtcc ggctcgtcggccacgcaccccatcagcgtccccggcgcgcgtcgccaccaccacctggtc aacctgccccccagccagacgggcctggtgcgccgctcgcgcaccgacagcttggccgcc acaccgccggccgccaagtgcaactcttgccgggtgcgcacggccagcgagggcgacggc ggcgtggcggcgggggccggggcggcgggcggcaggccggtgtcggtggcggggagcccc ctgagcccgggaccggtgcgcgcgcccctgagccgctcgcacaccctgagcggcggctgc ggcggccgcgcgagtaaggtgacgctggcgccggcagggggcgccctgcagcacagccgc tccatgtccatgcccgtggcgcactcgcccccggcggccgccaccagccccggcagcctg tcgtccagcagcgggcacggctcgggctcctatccgccgcccccgggcccgcacccgcac atgcagcaccccctgcacccccagcgaccctccagcggcagcgcctcggcctcgggctcc cccagcgaccctggcttcatgtccctggacgagtacggctcgagccctggggacctgaga gccttctgcagtctcaggagcaacacgcccgagtccatcgccgagacgcccccggccagg gacggcagcgggggcgagctgtacgggtacatgaccatggaccggcccctgagccactgc ggccgaccctaccgcagagtctccggggacggggcccaggacttggatagggggctgagg aaaaggacctactccctgaccacgcctgcccggcagcggccggtgccccagccctcctcc gcgtccctggatgaatacaccctgatgcgggccaccttctccggcagctcaggccgcctg tgcccgtcgtgccccgcgtcctcccccaaagtggcctaccacccctaccccgaggactac ggcgacatcgagatcggatcgcacaggagctccagcagtaacctgggcacggacgacggc tacatgcccatgacccccggcgtggccctcgcgggcggcggcgggagctgcaagagcgac gactacatgcccatgagccccaccagcgtgtccgccccgaagcagatcctgcagccgcgc gccgccgtcgcggccttgccccccacgggagccgcggggcccacgcccgcgtctgccgcc agcagggccttcccggggagcgggggcggctacaaaaccaactccccggccgagagctcc ccggaggacagcgggtacatgcgcatgtggtgcggaggctccaagctgtccgtggagagc gccgccgacggcaggctgcttccaaacggggactacctcaacatgtcccccggcgacgcg ggagcctcgggcaccccgcccgacttcttctcggccgtcctgcacgccggcggcggcggc ggcggcggggagatgctccggggcgtccccggctactgctacagctccctgccgcgctcc tacaaggccgcctacacctgcaacggggacaacgaccagtacgtgctcatgagctccccc gtagggcgcattctggaggaggagcggctggagtcgacggccagcccggggtccacgcag ccagccggcgccttcgcggccggggcagggggcggcggcggccacccgcagccaccccac ccggcggtaccttcgcccgggaggcccggtggcagcggcagcggccgcctggagggcttc ctgggccagcgctgtcgggccacgcggcccacgcgcctgtctctggaggggctgcagacc ctgacccgcatgcacgagtaccccctgccgcccgagcccaagagcccgggcgagtacatc aacattgacttcggcgaggcgggcgcgcgcctgtcgccgcccgcgcccccgctgctggcc tcggccgcctcgtcgtcgtcgctgctgtccgccggcagcccggcctcgtcgctgggctcg ggcaccccgggcacgagcggcgacagccggcagcgctccccgctctccgactacatgaac ctcgacttcagctcgcccaagtcaccccagccgggcggccaggccggggaccctgtgggc tccctggacgccctcctgtcccccgaggcctccgcgtacccgccgctgcccccgcgcccc gccgccccctcctcggccctgcagccggcgcccccgccgcccccgcccggagagctgtac cgcctgcctccggcacctgcctcccagggccctggcgcggcctcctctccatcctcgggg gcgggcgacagcggcgactacaccgagatggccttcggcgtggctgccacgccgccgcaa ccgatcgccgcgcccccgaagcccgacggggcccgcgtgagcagccccgtgtccggcctg aagaggctaagcctcatggaccaggtgtcgggggtcgaggccttcctgcaagccagccag cccccagacccgcaccgcggggccaaggtcatccgcgcggacccgcaagggggccgccgc cgccacagctcggagaccttctcctcgaccaccactgtgacccccgtgtccccgtctttc gcccacaaccccaagcgccacaactcggcctcggtggagaacgtgtctctcaggaaaagt ggcgaagggggcggcggcagcgtcctgggtggcggtgacgagccccccacgtccccccgc caattgccgccgccgctccacccgcaggcgcggccctggacgccgagccagcccgggggc ttggtcggctgccccgggggcagtggctcgccgatgcgccgggagacttctgctggcttc cagaacggcctcaactacatcgccatcgacgtgagggacgagcccgggctgtcgccgtcc cctcagcagcatcctcagacgggagacaagagcgcctggggccggacccggagcctcggg ggtctcatcggcgcggtaggggccggcagcaccggcggggtgtgtgtagggcccggccct ggcgccctgccctccgccagcacctacgccagcctcgacttcttgacgcatcacctgaaa gaggccacggtcgtgaaagagtga

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