KEGG   Delphinapterus leucas (beluga whale): 111179772
Entry
111179772         CDS       T05885                                 
Symbol
TRAF6
Name
(RefSeq) TNF receptor-associated factor 6 isoform X1
  KO
K03175  TNF receptor-associated factor 6 [EC:2.3.2.27]
Organism
dle  Delphinapterus leucas (beluga whale)
Pathway
dle04010  MAPK signaling pathway
dle04064  NF-kappa B signaling pathway
dle04120  Ubiquitin mediated proteolysis
dle04140  Autophagy - animal
dle04144  Endocytosis
dle04380  Osteoclast differentiation
dle04517  IgSF CAM signaling
dle04620  Toll-like receptor signaling pathway
dle04621  NOD-like receptor signaling pathway
dle04622  RIG-I-like receptor signaling pathway
dle04657  IL-17 signaling pathway
dle04722  Neurotrophin signaling pathway
dle04936  Alcoholic liver disease
dle05132  Salmonella infection
dle05133  Pertussis
dle05135  Yersinia infection
dle05140  Leishmaniasis
dle05142  Chagas disease
dle05145  Toxoplasmosis
dle05152  Tuberculosis
dle05160  Hepatitis C
dle05161  Hepatitis B
dle05162  Measles
dle05168  Herpes simplex virus 1 infection
dle05169  Epstein-Barr virus infection
dle05170  Human immunodeficiency virus 1 infection
dle05171  Coronavirus disease - COVID-19
dle05200  Pathways in cancer
dle05222  Small cell lung cancer
dle05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
dle05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dle00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    111179772 (TRAF6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111179772 (TRAF6)
   04064 NF-kappa B signaling pathway
    111179772 (TRAF6)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    111179772 (TRAF6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    111179772 (TRAF6)
   04140 Autophagy - animal
    111179772 (TRAF6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    111179772 (TRAF6)
   04621 NOD-like receptor signaling pathway
    111179772 (TRAF6)
   04622 RIG-I-like receptor signaling pathway
    111179772 (TRAF6)
   04657 IL-17 signaling pathway
    111179772 (TRAF6)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    111179772 (TRAF6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    111179772 (TRAF6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111179772 (TRAF6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    111179772 (TRAF6)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    111179772 (TRAF6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    111179772 (TRAF6)
   05161 Hepatitis B
    111179772 (TRAF6)
   05160 Hepatitis C
    111179772 (TRAF6)
   05171 Coronavirus disease - COVID-19
    111179772 (TRAF6)
   05162 Measles
    111179772 (TRAF6)
   05168 Herpes simplex virus 1 infection
    111179772 (TRAF6)
   05169 Epstein-Barr virus infection
    111179772 (TRAF6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    111179772 (TRAF6)
   05135 Yersinia infection
    111179772 (TRAF6)
   05133 Pertussis
    111179772 (TRAF6)
   05152 Tuberculosis
    111179772 (TRAF6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    111179772 (TRAF6)
   05140 Leishmaniasis
    111179772 (TRAF6)
   05142 Chagas disease
    111179772 (TRAF6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    111179772 (TRAF6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    111179772 (TRAF6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dle04131]
    111179772 (TRAF6)
   04121 Ubiquitin system [BR:dle04121]
    111179772 (TRAF6)
Enzymes [BR:dle01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     111179772 (TRAF6)
Membrane trafficking [BR:dle04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    111179772 (TRAF6)
Ubiquitin system [BR:dle04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    111179772 (TRAF6)
SSDB
Motif
Pfam: TRAF-mep_MATH MATH_2 zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-RING_UBOX zf-RING_2 zf-C3HC4_3 zf-C3HC4_4 zf-TRAF_2 zf-RING_5 Sina_ZnF Spc29 SlyX TRAF3_RING RING_XB3-XBAT31 DUF3450 U-box zf-RING_11 DUF4455 CCDC39 Myosin_tail_1 PspA_IM30 DUF16 PUMA_CC AAA_13 DUF7310 ATG16 Med21 HMMR_N Laminin_II DUF7607 EzrA UPF0242 TMF_DNA_bd DUF1664 CENP-F_leu_zip
Other DBs
NCBI-GeneID: 111179772
NCBI-ProteinID: XP_022439313
UniProt: A0A2Y9PAB2
LinkDB
Position
Unknown
AA seq 561 aa
MLLKIFLRRRKRAVDNHLTMSLLHWENSCGSSQSESDCCAAMAASSCGAAAKDESVSGTA
STVNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRD
AGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHRAHCEFALM
NCPQCQRPFQKCQLNIHIVKECPRRQVSCVNCAVSMAFEDKEIHDQNCPLANVICEYCNT
MLIREQMPNHYDLDCPTAPVPCTFSTFGCHEKMQRNHLARHLQEDTQSHMRMMAQAVQTL
SLAIAPAPQRGMLPCDSASLPRISSGCHSEVQNFQETIQQLEGRLVRQDHQIRELTAKME
TQSTYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFY
TGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAP
VRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST
RFDMGSLRREGFQPRSTDLGI
NT seq 1686 nt   +upstreamnt  +downstreamnt
atgctactcaaaatctttttgagaagaagaaaaagagcagtcgataatcaccttactatg
agtctgctacactgggaaaacagctgtggatccagccagtccgagagcgactgctgtgct
gccatggccgccagctcctgtggtgctgcagccaaagatgagagtgtgagtggaactgcc
agcacagtgaatctttccagctcttttatggaagagatccagggatatgacgtggaattt
gacccacccctggaaagcaagtatgaatgccccatctgcttgatggcattacgggaagca
gtgcaaacaccgtgcggccacaggttctgcaaagcctgcatcatcaaatcaataagggat
gcaggtcacaaatgtccagttgacaatgaaatactgctggaaaatcaactctttcctgac
aattttgcaaaacgagagattctttctctgatggtgaagtgtccaaatgaaggttgtctg
cacaagatggaactgaggcatcttgaggatcaccgagcacattgtgagtttgctcttatg
aattgtccccaatgccaacgtcccttccaaaaatgccaacttaatattcacattgtcaag
gagtgtccaaggagacaggtttcttgtgtaaactgtgctgtatcgatggcatttgaagat
aaagagattcatgaccagaactgtcctttggcaaatgtcatctgtgaatactgcaacacc
atgctcatcagagaacagatgcctaatcattatgatctagactgtcctacagccccagtt
ccatgcacattcagtacttttggttgccatgaaaagatgcagaggaatcacttggcacgc
cacctgcaagaggatacccagtcgcacatgagaatgatggcccaggctgttcagacttta
agccttgcgatagctcccgcacctcagcgtggcatgctgccatgtgattctgcctctctg
ccccggatttcctctgggtgtcactcagaggtccagaatttccaagaaaccattcaacag
ttagagggtcgccttgtaagacaagaccatcaaatccgggagctgactgcaaaaatggaa
actcagagcacgtatgtaagtgagctaaaacgaactattcgaacccttgaggacaaagtt
gctgaaatagaagcacagcagtgcaatggaatttacatctggaagattggcaattttggg
atgcacttgaaatctcaagaagaggagaaacctgttgtcattcacagccccggattctac
acaggcaaacccggctacaaactatgcatgcgcctgcacctgcagctaccaactgcacag
cgctgtgccaactacatatccctcttcgtccacacgatgcaaggagagtatgacagccac
ctcccgtggcccttccagggtacgatacgccttaccatccttgatcagtctgaagcacct
gtaaggcaaaaccatgaagagataatggacgccaaaccagagctgcttgccttccagaga
cccacaatcccacggaaccccaaagggtttggctatgtgacctttatgcatctggaagcc
ctaagacaaagaaccttcatcaaggacgacacgttattagtacgctgtgaggtctccacc
cgctttgacatgggcagtcttcggagggagggttttcaaccacgaagtactgacttgggg
atatag

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