Delphinapterus leucas (beluga whale): 111184253
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Entry
111184253 CDS
T05885
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle04120
Ubiquitin mediated proteolysis
dle04144
Endocytosis
dle04330
Notch signaling pathway
dle04668
TNF signaling pathway
dle04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
111184253 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
111184253 (ITCH)
04668 TNF signaling pathway
111184253 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
111184253 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
111184253 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dle04131
]
111184253 (ITCH)
04121 Ubiquitin system [BR:
dle04121
]
111184253 (ITCH)
Enzymes [BR:
dle01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
111184253 (ITCH)
Membrane trafficking [BR:
dle04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
111184253 (ITCH)
Ubiquitin system [BR:
dle04121
]
Ubiquitin ligases (E3)
HECT type E3
111184253 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
111184253
NCBI-ProteinID:
XP_022448327
UniProt:
A0A2Y9PYB3
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVIANGETTCSESASQNDDGSRPKDETRASTNGS
DHPEDAGSGENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagataactgtcatttcagcgaaacttaaagaaaataaaaagaattggtttgggccaagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaacctcttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacattgaaatctgatgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagaaccaacagagacaataggagatttgtcagtttgtcttgat
gggctgcagctagagtctgaagttattgctaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagagcgagcacaaatggatca
gaccatcctgaggatgcagggtctggtgaaaataggagggtcaatgggaacaattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggctcaccatctgccacttctgaaagtgat
ggctccagtacaggctctctcccaccaacgaatacaaattcaaatacatctgaaggagca
acatctggattaataattcctcttactatatctggaggttcaggccctaggccattaaat
cctgtacctcaagctcccctcccacccggttgggagcagagagtggaccagcatggacga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacgacgtggcagaggccaacattggaatccgtccggaactatgaacagtggcag
ctccaacgtagtcagcttcaaggagctatgcagcaatttaaccagaggttcatttatggg
aatcaagacttgtttgctacatcacaaaataaagaatttgatcccctgggtcccctgcca
cctggatgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaatact
cgtattacacaatgggaagaccccagaaatcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgaggttcacagtagatggaattccatattttgtggaccacaataga
agaacaaccacctatatagatccccgcactggaaaatctgccttagacaatggaccccag
atagcctatgtacgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataattactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgctatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatcttgaacaaaccagttggtctcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtatttttccgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaacattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgcggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcagtactttgatgcaaaggaattagaggttctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgagacttttgcagtttgttactggaacctgccgattgccagttggcgga
tttgctgacctcatggggagcaatgggccacagaaattctgcattgaaaaagttgggaaa
gaaaattggttgcctagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgctattgaagaaacagaaggatttgga
caagagtga
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