Delphinapterus leucas (beluga whale): 111188123
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Entry
111188123 CDS
T05885
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle04014
Ras signaling pathway
dle04072
Phospholipase D signaling pathway
dle04148
Efferocytosis
dle04360
Axon guidance
dle04625
C-type lectin receptor signaling pathway
dle04630
JAK-STAT signaling pathway
dle04650
Natural killer cell mediated cytotoxicity
dle04660
T cell receptor signaling pathway
dle04670
Leukocyte transendothelial migration
dle04722
Neurotrophin signaling pathway
dle04920
Adipocytokine signaling pathway
dle04931
Insulin resistance
dle05168
Herpes simplex virus 1 infection
dle05205
Proteoglycans in cancer
dle05208
Chemical carcinogenesis - reactive oxygen species
dle05211
Renal cell carcinoma
dle05220
Chronic myeloid leukemia
dle05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
111188123 (PTPN11)
04630 JAK-STAT signaling pathway
111188123 (PTPN11)
04072 Phospholipase D signaling pathway
111188123 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
111188123 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
111188123 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
111188123 (PTPN11)
04660 T cell receptor signaling pathway
111188123 (PTPN11)
04670 Leukocyte transendothelial migration
111188123 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
111188123 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
111188123 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
111188123 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
111188123 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
111188123 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
111188123 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
111188123 (PTPN11)
05211 Renal cell carcinoma
111188123 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
111188123 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
111188123 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
dle01009
]
111188123 (PTPN11)
Enzymes [BR:
dle01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
111188123 (PTPN11)
Protein phosphatases and associated proteins [BR:
dle01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
111188123 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
111188123
NCBI-ProteinID:
XP_022456026
UniProt:
A0A2Y9QEG1
LinkDB
All DBs
Position
Unknown
AA seq
623 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPYPNQMFLLINIIFFKD
GESEAKERYSIDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPRKSYIATQGCL
QNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAH
DYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIT
DAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ
YRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLTDQATGDQSPLPPCTPTPSCA
EMREDNARVYENVGLMQQQKSFR
NT seq
1872 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaatatcactggcgtggaggcagaaaacctactg
ttgacaagaggagttgatggcagttttttggcaaggcccagtaaaagtaaccctggagac
tttacactttctgttagaagaaatggagctgtcacccacatcaagattcagaacactggt
gattactatgacttgtatggaggggagaagtttgccactttggctgaattggtccagtat
tacatggaacatcatgggcaattaaaagagaagaatggagatgttattgagctcaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcatggacatctgtctgggaaa
gaagcagagaaattattaaccgagaaaggaaaacacggtagctttcttgtgcgggagagc
cagagccaccctggagattttgttctctctgtccgaaccggagatgacaaaggggagagc
aatgacggcaagtctaaagtgacccatgttatgatccgctgtcaggaactgaaatatgat
gttggtggaggagaacggtttgactctttgacagatctcgtggagcattacaagaagaat
cctatggtagaaacattgggcacagtactacaactcaagcagcccctcaacacaactcgt
atcaatgctgctgaaatagaaagtcgggttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggaatgcaaa
cttctctacagcagaaaagagggtcagaggcaagagaataaaaacaaaaatagatataaa
aacatcctgccctatcccaatcagatgtttcttctgattaacatcatattctttaaagat
ggggagtctgaagcaaaagaacgttattctattgaccacaccagggttgtcctacacgat
ggtgatcccaatgagcctgtttcagattacatcaacgcaaacatcatcatgcctgaattt
gaaaccaagtgcaacaactcaaagcccagaaagagttacattgccacacagggctgcctg
caaaacacagtgaatgacttttggcggatggtgtttcaagagaactcccgagtgattgtc
atgacaacaaaagaagtggagagaggaaagagtaaatgtgtcaaatactggcctgatgag
tatgcgctaaaagaatacggggtcatgcgcgttaggaacgtcaaagaaagtgctgctcat
gactatacgttaagagaacttaaactttcgaaggttggacaagctctactccaggggaat
acggagagaacggtctggcaataccactttcggacctggccggaccacggagtgcccagt
gaccccgggggcgtgctggacttcctggaggaggtccaccataagcaggagagcatcacg
gacgcggggcctgtggtggttcactgcagtgctggaattggccgaacagggacgttcatt
gtgattgatattcttattgacatcatcagagagaaaggtgtcgactgtgacattgacgtt
cccaaaaccattcagatggtgcggtctcagaggtcagggatggtccagacagaagcacag
taccgattcatctatatggccgtccagcattatattgaaacactacagcgcaggattgaa
gaagagcagaaaagcaagaggaaagggcacgaatacacaaatattaagtattccctgacg
gaccaggcaactggagatcagagtcccctcccgccttgtaccccaacgccgtcctgtgca
gaaatgagagaagataatgctagagtctatgaaaatgtgggtctgatgcagcagcagaaa
agtttcagatga
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