KEGG   Drosophila melanogaster (fruit fly): Dmel_CG14887
Entry
Dmel_CG14887      CDS       T00030                                 
Symbol
Dhfr
Name
(RefSeq) dihydrofolate reductase, isoform B
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme00670  One carbon pool by folate
dme00790  Folate biosynthesis
dme01100  Metabolic pathways
dme01240  Biosynthesis of cofactors
dme04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:dme00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    Dmel_CG14887 (Dhfr)
   00670 One carbon pool by folate
    Dmel_CG14887 (Dhfr)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Dmel_CG14887 (Dhfr)
Enzymes [BR:dme01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     Dmel_CG14887 (Dhfr)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 42003
NCBI-ProteinID: NP_001036720
FlyBase: FBgn0004087
UniProt: P17719 G4LU61
LinkDB
Position
3R
AA seq 182 aa
MLRFNLIVAVCENFGIGIRGDLPWRIKSELKYFSRTTKRTSDPTKQNAVVMGRKTYFGVP
ESKRPLPDRLNIVLSTTLQESDLPKGVLLCPNLETAMKILEEQNEVENIWIVGGSGVYEE
AMASPRCHRLYITKIMQKFDCDTFFPAIPDSFREVAPDSDMPLGVQEENGIKFEYKILEK
HS
NT seq 549 nt   +upstreamnt  +downstreamnt
atgcttcgattcaatttaatcgtggcagtttgcgagaatttcggaatcggcatcagaggc
gatctaccatggcgcattaaatctgagctgaagtacttcagccgcaccaccaagcgaaca
agtgatcccaccaagcaaaatgccgtggtaatgggcaggaaaacctacttcggagtgccg
gaaagcaagaggcctcttcccgatcggctgaacatagtgctgagcaccacacttcaggaa
agtgatctgcccaagggagtactattgtgccccaatctcgagacggccatgaagatcctt
gaggagcagaacgaagtggagaacatttggattgtgggcggtagtggagtctacgaggag
gccatggcctcgccaaggtgtcaccggctgtacattaccaaaataatgcagaagttcgat
tgcgacacctttttccccgcgatccctgacagctttcgagaggtcgcgcccgattccgac
atgccactgggtgtgcaggaggagaatggcattaaattcgagtacaagattttggagaaa
cactcataa

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