| Entry |
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| Symbol |
PEK
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| Name |
(RefSeq) pancreatic eIF-2alpha kinase, isoform A
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| KO |
| K08860 | eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1] |
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| Organism |
dme Drosophila melanogaster (fruit fly)
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| Pathway |
| dme04141 | Protein processing in endoplasmic reticulum |
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| Brite |
KEGG Orthology (KO) [BR:dme00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
Dmel_CG2087 (PEK)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
Dmel_CG2087 (PEK)
04137 Mitophagy - animal
Dmel_CG2087 (PEK)
09143 Cell growth and death
04214 Apoptosis - fly
Dmel_CG2087 (PEK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:dme01001]
Dmel_CG2087 (PEK)
Enzymes [BR:dme01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
Dmel_CG2087 (PEK)
Protein kinases [BR:dme01001]
Serine/threonine kinases: Other
PEK family [OT]
Dmel_CG2087 (PEK)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
3R
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| AA seq |
1162 aa
MQDDLDGIVRHRRRSLSFLQIVTLTMAGLVAFDPAQVLAGHPTTDSELQTAGSPRPPGLE
HCVDQEERRVARRLLYISTLDGRLSALDIAKSGKLRWSVPTGPGPLISSSIHRLELTNNG
QFVRMIPSLSGGIYKFDGDSIDPIPITAEHLLSSSAKFSDDLVISGGKETRSYGVSVRTG
QLLYECSLNGCVNSTEEGLAIDDTIREPDEEDQLEDGEQLRDEAGYIVRHDPLLDDVIIV
RRQTQTVRAVESRTGVERWNFSVGQHELDLVRPSECQLQPRDELELAVLDVDIKVVVPEG
IICAFSKSEPQTMLWKYKFDHPIVSAWNTNADDELQPIDLFSSAQWLWDQDENDTELPNA
PQSPPSIYLGMYDKQLYIQESIRLRQEIMDQTKVYQQLTGDTSLMPRIPWKPISASSKSL
VIFRKDQEDPEMIAEGAVAQGGELVPYDDENFAVAAQSVLNASEFVNGNGFYFYTTGDLN
GPQECSTQNNPTDLPAITAPTSPTNATSEGTEATGNHSVNDDLGFSLDDIDAPVKVVILS
LWFWWKEIVVIAFTSAVILNIFMGQRNQRVEREYLVIERHVPVQTAIEATEASTQALLGP
VVPMQRPGNRFSFPPGQANQRTISESTTHSGEHYTSRFQSDFELMQCLGRGGFGVVFEAK
NKLDENRYAIKRITLPNKESSRQRVLREARTLASCEHHNIVRYFHSWTETPPTGWQEEED
RKLLAHELSTSIQIETPDDSTMPSLTEQLKEKRQQQLLSWVSDAANSTACSHDFHLPGES
SLKNIREEYDYDEEEDSLIEFRSESQSAALRAEEEDDTDDDYEEDEEQQGDHEKRHRSSV
SIDIHSASFDLKNINYSQHQLVSNSFQIESVRPKSSGSDDANDDNKARRKPLTLALAQNH
NNNQNGSQPTPSSATILNGTVAKPSKVYLYIQMQLCRKESLRDWLRDNRSETRAAHIGDI
FHQIVDAVDYVHLKGLIHRDLKPSNIFFSQDGQIKIGDFGLVTDMADIPNLVAKCGDQSG
LPSCARHTQQVGTHLYMSPEQLLGQHYDYKVDIYSLGLIFFELHVYFSTEMERIKTLRSL
RDGQYPKDFAVNYPQQYDLLQQMLSAQPEQRPQTKQLKSQLRNILQLPHLLSEGQSEQAE
LAERARRLSRSRTFSSSSEPHQ |
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| NT seq |
3489 nt +upstreamnt +downstreamnt
atgcaggacgacctggatggcatcgtgaggcatcgtcgccggagcctgagcttcctgcag
atcgtcacgctcactatggccggcctggtggctttcgatcccgcccaggtgctagctggg
cacccaactactgattcggagctccagactgccggatctccccgtccccccgggctcgaa
cactgcgtagatcaggaggagcgtcgcgttgcaagaagactcctatacatttccacgctt
gatggtcgactgagcgctctggacatcgccaagtccggcaaactgcgctggagtgtgccc
accggaccggggccactaatctcgtccagcatccatcgattggagctgaccaacaatggg
cagttcgtacgcatgattccctctttgagcggcggcatctacaagttcgacggggactcc
atcgatcccattccaatcacggcggagcacctactcagctcgagcgccaaattcagcgat
gatctggttatatccggaggcaaggagacacgctcatacggtgtttccgttcgcactggc
cagctgctgtatgaatgttctctaaacggatgtgtaaactctacggaggaagggcttgca
atcgacgacaccattagggagcccgatgaggaggatcagctggaggacggagaacagtta
agggacgaggccggctacatagtgcgccatgatcctctccttgacgacgttattatcgtc
cgccgccagacacaaacggttcgggccgtggaatcccggaccggagtggagcgttggaac
tttagcgtaggtcagcatgagttggatctggtgagaccttccgagtgccagctacagccg
cgcgatgagctggagctggctgttttggatgtggatataaaggtggtagtgcccgaggga
attatctgcgccttcagcaaaagtgagccacagactatgctgtggaagtacaagtttgat
cacccaattgtgagtgcctggaatacaaatgccgacgacgaattgcagcctattgatttg
tttagctcggcccagtggctttgggaccaggacgaaaatgacacggagctgcccaatgcg
ccacaaagcccgccatccatctacttgggcatgtacgataaacagttgtatattcaggag
tcaatacgtctacgccaggagattatggaccagaccaaggtctatcagcagcttacaggc
gacaccagcctgatgcccaggattccctggaagccgatatccgccagtagcaaatcgctg
gtaatcttccggaaagaccaggaggaccctgaaatgattgctgagggagctgtggcacaa
ggaggggaactggtgccctatgatgatgaaaacttcgctgtggcagcgcagtccgtattg
aatgcatcggagtttgtcaatggcaatggtttttacttctacaccactggcgatctgaac
ggcccgcaagagtgcagtacgcagaataatccaactgaccttccagcaatcacagctcca
acatcgcctaccaatgccacatctgagggaacggaagctactggaaaccatagcgtcaac
gacgatttgggctttagtttggatgacattgatgcgcctgtaaaggttgtgatattgtcg
ttgtggttctggtggaaggaaatcgtggtcatagcatttacgtcggctgtgattctaaat
attttcatgggccaacgaaaccagcgcgtggagcgagagtatctggtcattgaacgtcat
gtgcctgttcaaacggccatcgaggccaccgaagcatccacacaggctttactaggtcca
gtggtgccgatgcagcgacctggaaatcgttttagcttcccacctggacaagcaaatcag
cgcaccatttcggagtctacaactcattcaggcgagcattacacttcccgctttcagtcc
gacttcgagttgatgcagtgccttggtcgcggtggtttcggagtggtcttcgaagctaag
aacaagctggatgagaaccgatacgccattaagcgcataacgctacccaataaggaatct
tcaagacagcgagtccttcgcgaggctcgaactttggctagttgtgagcaccacaacatc
gtgcgatacttccattcctggaccgagacaccgccgactggttggcaggaagaagaggat
cgcaagctgcttgcccacgagctgtccacctctatccagatagagacgccggacgatagt
acaatgccttcgttgacggagcagttgaaggagaaacgccaacagcagctcttgtcctgg
gtttcggatgcagccaatagcaccgcttgtagtcacgactttcatctaccaggcgagtca
tcactcaagaacatacgcgaggagtacgactacgatgaggaagaggactcgctcattgaa
ttccgcagcgagtcgcagtcagccgctttacgggcagaggaggaggatgataccgacgac
gactatgaagaggatgaagagcagcagggagaccatgagaaacgacatcgcagctccgtg
tccattgacatccattcggcctcgtttgaccttaagaacataaactactcacagcaccaa
ctggtctccaattcgtttcaaatcgaatctgtgcgccccaagagcagtggaagtgatgat
gcgaatgacgataataaagctagaaggaagccccttaccttggcactggcccagaatcac
aataacaaccaaaacgggagccaacctacgccctccagtgccacgattctgaacggaacg
gtggccaagcccagcaaggtgtacctctacatccagatgcagctatgccgcaaggagagt
ctgcgcgactggttaagggacaaccggtcggaaacaagggctgcccacattggtgacatt
tttcaccagatcgttgatgccgttgactatgtacatttgaagggtctgattcatcgggac
ctgaaaccaagcaacatattcttctcgcaggatggacagataaagattggagacttcggg
ctcgtcaccgacatggccgatatccccaacctggtggccaagtgtggggaccagagtggc
ctgccctcctgtgcccgccacacccagcaggtgggcacccacttatacatgtcgccggag
cagcttttgggccagcactacgactacaaggtggacatctattcactgggactgatcttc
ttcgagctgcacgtgtacttcagcactgaaatggagcggatcaagacactgcgcagtctt
cgggacggccagtatcccaaggatttcgctgtcaattacccgcagcagtacgacttgctc
cagcaaatgctatccgcccagccagagcaacgcccgcagaccaagcagttgaaaagccag
ctgcgcaacattctgcagctacctcatctcctctcggaaggacaaagcgagcaggcggag
ctggcggagcgggccaggcgcctgagtcgcagccgcaccttcagcagctccagtgagccg
catcagtga |
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