Dipodomys merriami (Merriam's kangaroo rat): 138808438
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Entry
138808438 CDS
T11079
Symbol
Acacb
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer00061
Fatty acid biosynthesis
dmer00620
Pyruvate metabolism
dmer00640
Propanoate metabolism
dmer01100
Metabolic pathways
dmer04152
AMPK signaling pathway
dmer04910
Insulin signaling pathway
dmer04920
Adipocytokine signaling pathway
dmer04922
Glucagon signaling pathway
dmer04931
Insulin resistance
dmer04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
138808438 (Acacb)
00640 Propanoate metabolism
138808438 (Acacb)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
138808438 (Acacb)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
138808438 (Acacb)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
138808438 (Acacb)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
138808438 (Acacb)
04922 Glucagon signaling pathway
138808438 (Acacb)
04920 Adipocytokine signaling pathway
138808438 (Acacb)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
138808438 (Acacb)
04931 Insulin resistance
138808438 (Acacb)
Enzymes [BR:
dmer01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
138808438 (Acacb)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
138808438 (Acacb)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
138808438 (Acacb)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
138808438
NCBI-ProteinID:
XP_069850771
LinkDB
All DBs
Position
Unknown
AA seq
2449 aa
AA seq
DB search
MVLLLFLSCLIFSCLTFSWLKIWRKMTDSSPVTNSKLEASLILNQEPIPASDNSEEQLQT
NDGDSSQPKTPKQAEPASHKSPSDACQQEDSQTPHSSHDTWPTPELQVNGTETQGPEPPD
TYGLSSPAKPQGQRARSPSKEDKKQAHIKRQLMTNFILGSFDDNSSDEDSGAGILRESSR
KGSRASLGTLSPEAAMIASEADTLMPAMRPSMSGLHLVRRGREHKKLDLHRDFTVASPAE
FVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAE
YIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKHGI
AFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWAEENLQQGTPIHIPEDVY
SLGCVKDVDEGLEAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPMLFRQVQSEIPGSPI
FLMKLAQHARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATAAVFEFMEQ
CAVLLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAM
GVPLYRLKDIRLLYGESPWGVTPISFETPTNPPIARGHVIAARITSENPDEGFKPSSGTV
QELNFRSSKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGD
FRTTVEYLINLLETESFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNVADAKFRD
CMTDFLHSLERGQVLPADSLLNIVDVELIYGGVKYILKVARQSLTTFVLIMNGCHIEIDA
HRLNDGGLLLSYNGNSYTTYLKEEVDSYRITIGNKTCVFEKENDPTILRSPSAGKLTQYT
VEDGGHVEAGSSYAEMEVMKMIMTLNVQESGHVKYIKRPGAVLEAGCVVGRLELDDPSKV
HPAEPFTGELPTQQTLPILGEKLHQVSHNVLENLSNIMSGYCLPEPIFSIKLKEWVQKLM
MTLRHPSLPLLELQEIMTSVAGRIPTPVEKAVRRVMAQYASNITSVLCQFPSQQIATILD
CHAATLQRKADREAFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRRYLNVEHYFQQAHY
DKCVISLREQFKPDMTQVLNCIFSHAQVAKKNQLVIMLIDELCGPDPTLSDELTSILNEL
TQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILS
ETTIFDVLPTFFYHTNKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPS
SHPNRMVMPISVTNPDLLRHSTELFMDSGFSPLSQRMGAMVAFKRFEDFIRNFDEVISCF
ANLPADTPLFSKARTSLYSEEDSKNLREEPIHILNVAIQCADHLEDEALVPIFRTFVQSK
KHILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFD
LTAVPCANHKMHLYLGAAKVKEGTEVTDHRFFVRAIVRHSDLITKEASFEYLQNEGERLL
LEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRSMVMRYGSRLWKLRVLQ
AEVKINIHQTAAGSAVPVRLFITNESGYYLDISLYKEVTDPRSGSIMFHSFGNKQGSQHG
MLINTPYVTKDLLQAKRFQAQSLGTTYIYDFPEMFRQALFKLWTSPDKYPKDILTYTELV
LDPQGQLVEMNRLPGGNEVGMVAFKMRMKTPEYPEGRDVVVIGNDITFRIGSFGTGEDLL
YLRASELARAEGIPQIYLAANSGARIGLAEEIKHMFQVAWVDPEDPHKGFKYLYLTPQDY
TRTSSLNTVHCRHVEEGGESRYVVTDIIGKDDGLGVENLRGSGMIAGESSLAYDEIVTIS
MVTCRALGIGAYLVRLGQRVIQVDNSHIILTGASALNKVLGREVYTSNNQLGGVQIMYHN
GISHITVPDDFEGVYTILEWLSYMPKDNRSPVPIITPTDPIDRDVEFVPSRAPYDPRWML
AGRPHPTLSGAWQSGFFDQGSFREIMAAWAQTVVTGRARLGGIPVGVIAVETRTVEVAVP
ADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREKLPLLIFANWRGFSGGMKDMYD
QVVKFGAYIVDGLRQYTQPILIYIPPYAELRGGSWVVLDSTINPLCIEMYADRESRAGVL
EPEGTVEIKFRRKDLVKTMRRIDPTYKKLVEQLGMSQLSDEDRKDLEARLKAREELLLPI
YHQVAVQFADLHDTPGRMLEKGVISDVLEWRTSRAFLYWRLRRRLLEDQVKREVLQASSE
LSHDHVQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWLEGEGLRSTIRENIKYLKRD
SVLKTIQGLVQKTPEVAADCTIHLSQQLSPAERAQVVKLLTSAERPAST
NT seq
7350 nt
NT seq
+upstream
nt +downstream
nt
atggtcttgctccttttcctctcttgcctgattttctcctgcctgacgttttcctggtta
aaaatctggagaaaaatgacagactccagcccagtgaccaacagtaagttggaagcgagt
ctcatcctgaatcaggagcccattccagcctcagacaactcagaggagcagctgcaaaca
aatgatggtgacagctcccagccaaagactcctaaacaggccgagccggcctcccataaa
agccccagcgatgcctgtcagcaggaagactctcagaccccacattcttcccatgacacc
tggcccactccagaactgcaagtcaatgggacagagacccaaggcccagagcccccagac
acctacggcctgtcctccccagccaagccccagggccagcgagccagatccccatccaaa
gaggacaagaagcaggcccacattaagaggcagctcatgaccaacttcatcctgggctcc
tttgatgacaactcttccgatgaagactctggggctggcattttacgagagtcttcccga
aagggcagtcgggctagcctgggcaccctgtccccagaggctgctatgattgcaagtgaa
gctgacacccttatgccagctatgaggccgagcatgtcaggactccacctcgtgaggcgg
ggccgtgagcacaagaagctggacctgcaccgagacttcaccgtggcctccccggccgag
ttcgtcacgcgatttggtggggatcgggtcatcgagaaggtgctcattgccaacaacggc
atcgctgcggtgaagtgcatgcgttccatccgcaggtgggcttatgagatgttccgcaat
gagagagccatacgcttcgtggtcatggtgaccccggaggacctcaaggccaacgcagag
tacatcaagatggcagaccagtacgtccctgtgccaggaggaccgaataacaataactat
gccaacgtggaactgattgtggacattgccaagaggatccctgtgcaggcggtgtgggct
ggctggggccatgcttccgaaaaccccaaacttccggagctgctgtgcaagcatgggatt
gctttcttaggtccccccagtgaagccatgtgggccttaggagataagattgcttccacc
atcgtggctcagaccctgcagatcccaaccctgccctggagtggaagtggtctgacggtg
gagtgggcagaggagaacctgcagcaggggacacccatccacatccccgaagatgtctac
agcctgggctgtgtgaaggatgtagacgagggcttggaggcagcagaaaagattggtttt
ccattgatgatcaaggcttctgaaggcggtggagggaaaggaattcgaaaggctgagagc
gccgaggattttcccatgctgttcagacaagtgcagagcgagatcccgggctctcccatc
tttctcatgaagctggcccagcacgcgaggcacctggaggtccaggtgctggctgaccag
tatgggaacgctgtgtcgctgtttgggcgggactgctccatccagaggcgccaccagaag
atcatcgaggaggcgccggctaccatcgccacggcagctgtgtttgagttcatggagcag
tgtgcggtgctcctggccaagaccgtgggctacgtgagtgccggaaccgtggaatacctg
tacagccaggacggcagcttccacttcctggagctgaaccctcgcttgcaggttgaacat
ccctgcacagagatgattgccgacgtcaacctgccggccgcacagctgcagattgccatg
ggtgtgccgctgtacaggctgaaggacatccggcttctctatggagagtctccatggggg
gtgacgcccatttcctttgagactcccaccaaccctccaatcgccaggggccatgtcatt
gcagccaggatcaccagcgaaaacccagacgaggggtttaagccgagctcagggacagtc
caggaactgaacttccgcagcagcaagaatgtgtggggctacttcagcgtggcagccgcc
ggaggcttacatgagtttgctgactcccaattcgggcactgcttctcctggggcgagaac
cgtgaagaggccatttcgaacatggtggtggctttgaaggagctgtccatccggggtgac
ttcaggaccacggtggaatatctcatcaacctgctggagactgagagcttccagaacaac
gacattgacactgggtggctggatcacctcatcgctgagaaagtgcaggcagagaagcca
gacatcatgctcggggtggtatgcggggccttgaacgtggccgatgcgaagttcagagac
tgtatgacggatttcctgcactccctggaaaggggccaggtcctccctgcagattcgctg
ttgaacattgtggacgtagagttaatttacggaggtgtcaagtacattctcaaggtggcc
cggcagtccctgaccacgttcgttctcatcatgaatggctgccacatcgagatcgacgcc
caccggctgaacgacgggggtcttctgctctcctacaacggcaacagctacaccacctac
ctgaaggaagaggtggacagttaccggatcaccataggcaacaagacatgtgtgtttgag
aaggagaacgaccccaccatcctgaggtccccgtcggctgggaagctgactcagtacacg
gtggaggacgggggccatgtggaagcggggagcagctacgctgagatggaggtgatgaag
atgatcatgaccctgaacgtgcaggagagtggccacgtgaaatacatcaagcggccagga
gccgtgctggaagctggctgtgtggtgggcaggttggagctcgatgacccatctaaagtg
cacccggcagagccgttcacaggagagctccctacccagcagacgctccccatcctcggc
gagaagctacaccaggtgtcgcacaatgtcctggaaaacctgagcaacatcatgagtggc
tactgcctgccagagccgatttttagcatcaagctgaaggagtgggtgcagaaactcatg
atgactctccggcacccatcgctgccgttgctggagctgcaggagatcatgaccagcgtg
gcaggccgcatccccacccccgtggaaaaggcggtccgcagggtcatggcccagtacgcc
agcaacatcacctcggtgctgtgccagttccccagccagcagatagccaccatcttggac
tgtcacgcggccaccctgcagcgcaaggctgaccgagaggcctttttcatgaacacacag
agcatcgtgcagttggtccagaggtaccgcagtgggacccggggctacatgaagacggtg
gtactggacctcctgcggagatacttgaatgtcgagcactatttccaacaagcgcattat
gacaagtgtgtgatcagcctccgggagcagttcaagccagacatgacccaggtgctgaac
tgcatcttttcacatgctcaggtggccaagaagaaccagctggtgatcatgctgatcgat
gagctgtgtggtccagaccccacgctgtcggatgagctgacctccatcctcaacgagctc
actcagctgagcaagagcgagcactgcaaagtggccctgcgagctagacaggtgctcatc
gcctcccacctgccctcctacgagctgaggcacaaccaggtggagtccatcttcctgtcg
gccatagacatgtacggccaccagttctgcccagaaaacctcaagaaactaatcctttcg
gagacaaccatctttgacgtgctgcccacattcttctaccacactaacaaagttgtctgc
atggcatcactagaggtttacgtccggagagggtacatcgcctatgagttgaacagcttg
cagcaccgtgagctcccagacggcacctgtgtggtagagttccaattcatgctgccttct
tcccacccaaaccggatggtcatgcccatcagcgtcaccaatccagacctcctgagacac
agcaccgagctcttcatggacagcggcttctccccgctctcacagcgcatgggagccatg
gtcgccttcaagaggttcgaggatttcatcaggaactttgacgaggtcatttcctgcttt
gccaacctccccgcagacacgcccctgttcagcaaggcccgcacctccctgtactcggag
gaggacagcaagaaccttcgggaagagcccatccatatcctgaacgtggccatccagtgt
gccgaccacctggaggatgaggccctggtgccgattttccggacttttgtacagtccaag
aaacatatcctggtggactatggtctccgaagaatcacattcctgattgcccaagagaaa
gaatttcccaagtttttcaccttcagagccagagatgagtttgcagaagaccggatatat
cgtcacttggagccggccctggccttccagctggagctcagccgcatgcgcaacttcgat
ctgaccgctgtgccctgtgccaaccacaagatgcatctttacctgggcgctgccaaggtg
aaggaaggaacggaagtgacagaccacaggttcttcgtccgggccattgtcaggcactcg
gatctgatcaccaaggaggcctccttcgagtacctgcagaacgagggcgaacggctgctc
ctggaggccatggacgagctggaggtggccttcaacaacaccagcgtgcgcaccgactgc
aaccacatcttcctcaatttcgtgcccaccgtcatcatggaccccttcaagatcgaggag
tccgtgcgctccatggtgatgcgctatggcagccggctgtggaagctgcgcgtgctgcag
gccgaggtgaagatcaacatccaccagactgccgccggcagcgccgtgcccgtccgcctg
ttcatcaccaacgagtcgggctactacctggacatcagcctctacaaggaagtgaccgac
cccagatctggaagcatcatgtttcactcctttggcaacaagcaagggagccagcatggg
atgctcatcaacaccccctacgtgaccaaggacctgcttcaggccaagagattccaggca
cagtccctggggaccacctatatctacgacttcccagaaatgttcagacaggctctcttt
aaactctggacctccccagacaaataccccaaagatatcctgacatacacggagttagtg
ttggaccctcagggccagctggtagagatgaaccgacttcctggaggaaatgaggtgggc
atggtggccttcaaaatgcggatgaagaccccggagtacccagaagggcgggatgtggtt
gtcatcggcaatgacatcaccttccgcatcgggtccttcggcactggggaagaccttctg
tacctgcgggcctctgagctggcccgggcggagggcatcccccaaatctacctagcagcc
aacagtggggcccgcattggcctggcagaagagatcaaacacatgttccaggtggcctgg
gtggatccagaagacccccacaaaggctttaagtacctgtacctgaccccccaagactac
acgcgaacgagctctctgaacaccgtgcactgcagacacgtcgaggaaggaggagaatcc
aggtacgtcgtcaccgacattattgggaaggatgacggcctgggtgtggagaatctcagg
ggctctggcatgatagctggggagtcctccctggcttacgacgagatcgtcaccattagc
atggtcacctgccgagccctgggcattggggcctatttggtacgcctgggccagagggtg
attcaggtggacaattcccacatcatcctgacgggcgcgagtgccctcaacaaggtcctg
ggaagagaggtctacacgtctaacaaccagctgggtggcgtgcagatcatgtaccacaac
ggcatctcccacatcacggtgcccgatgactttgagggtgtctataccatcctggagtgg
ctgtcctatatgccaaaggataatcgcagcccagtccccatcatcacacccactgacccc
atcgacagagatgtggagtttgtcccatccagagctccctacgatccccggtggatgctt
gcgggaagacctcacccaacgctgagcggggcttggcagagtggattcttcgatcagggc
agcttcagggagatcatggcggcctgggcccagacggtggtgacgggccgagcgaggctg
gggggcatccccgtgggcgtcatcgccgtggagacgcggacggtggaggtggccgtccct
gccgaccccgccaacctggattccgaggccaagatcatccagcaggccggccaggtgtgg
ttcccggactccgcatacaaaacggcgcaggccatcaaagacttcaaccgggagaagctg
cccctgctgatcttcgccaactggaggggcttctccggagggatgaaagacatgtacgac
caggtggtgaagttcggggcctacatcgtggacggcctccggcagtacacacagcccatc
ctcatctacatacccccctacgccgagctccgcgggggctcctgggtggtcctcgactcc
accatcaaccccctgtgcattgagatgtatgcggacagggagagcagagcgggggttctg
gagccggaaggcacggtggagattaagttccgaaggaaggacctggtaaagaccatgaga
aggatcgacccgacctacaagaagcttgtggaacagctggggatgtctcagctctccgat
gaggacaggaaggacctggaagcccggctgaaggcgcgggaagagctgcttctccccatc
taccaccaggtggcggtgcagttcgccgacctgcacgacacgccgggcaggatgctggag
aagggcgtcatctcggacgtgctggagtggaggacctcgcgggccttcctgtactggcgg
ctgcgccgccggctgctggaggaccaggtgaagcgggaggtcctgcaagccagcagcgag
ctcagtcacgaccacgtgcagtccatgctgcgccgctggttcgtggagaccgagggcgcc
gtcaaggcctacctgtgggacaacaaccaggtggtggtgcagtggctggagcagcactgg
ctggagggcgagggcctgcgctccaccatccgcgagaatatcaagtacctcaagcgggac
tcggtgctcaagaccatccagggtctggtgcagaaaacccccgaggtagcggcggactgc
accatccacctgagccagcagctcagccctgccgaacgggcgcaggtggtgaagctgctg
accagcgccgagcggcccgcatccacctga
DBGET
integrated database retrieval system
