Dipodomys merriami (Merriam's kangaroo rat): 138816902
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Entry
138816902 CDS
T11079
Symbol
Itch
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer04120
Ubiquitin mediated proteolysis
dmer04144
Endocytosis
dmer04330
Notch signaling pathway
dmer04668
TNF signaling pathway
dmer04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
138816902 (Itch)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
138816902 (Itch)
04668 TNF signaling pathway
138816902 (Itch)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
138816902 (Itch)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
138816902 (Itch)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dmer04131
]
138816902 (Itch)
04121 Ubiquitin system [BR:
dmer04121
]
138816902 (Itch)
Enzymes [BR:
dmer01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
138816902 (Itch)
Membrane trafficking [BR:
dmer04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
138816902 (Itch)
Ubiquitin system [BR:
dmer04121
]
Ubiquitin ligases (E3)
HECT type E3
138816902 (Itch)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
138816902
NCBI-ProteinID:
XP_069863199
LinkDB
All DBs
Position
Unknown
AA seq
860 aa
AA seq
DB search
MSDSGSQFGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVIVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLRFRVWSHQTLKSDVLLGTAALDVYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSICLDGLQLDADVVTNGETTCSESTSQNEDGSRPKDETRVNTNGS
DDPDDSGSGENRRTNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSTTSESD
GSSTGSLPSTNTNTSEGATSGLIIPLTISGGSGPRPLNTVTQAPLPPGWEQRVDQHGRVY
YVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQ
RSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDNNGRVYFVNHNTRI
TQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQIA
YVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPG
EEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGR
FIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEM
YFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNE
ILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEK
RMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSY
EQLKEKLLFAIEETEGFGQE
NT seq
2583 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagtttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatctcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtagaagtcatagtagatggacagtcaaagaagacagaaaagtgtaacaataca
aacagtcccaaatggaagcaaccccttacagttattgttacccctgtgagtaaattacgt
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcacta
gatgtttatgaaacattaaagtcaaacaatatgaaacttgaagaagtggttgtgactttg
cagcttgtaggtgacaaagagccaacagagacaataggagacttgtcaatttgtcttgat
gggctgcagttagatgctgatgttgttactaatggtgaaactacatgttcagaaagtacc
tcacagaatgaggatggctctagacccaaggatgaaacaagagtgaacacaaatggatca
gatgaccctgatgattcagggtctggtgaaaataggagaaccaatgggaacaattctcca
tcactctccaatggtgggtttaagccttctagacctccaagaccttcacgaccacctcca
cccacacctcgaagaccagcatctgtcaatggctcaccatctaccacttctgaaagtgat
ggatctagtactggttctctaccatcaacaaatacaaatacctctgaaggagcaacatct
ggattaataattcctctaactatttcaggaggctcaggtcctagaccattaaatactgta
actcaagctcccctaccacctggatgggaacagagagtggaccagcatgggcgagtttat
tatgtagatcatgttgaaaaaagaacaacatgggatagacctgaacctctacctcctggc
tgggagcggcgggttgacaatatgggacgtatttattatgttgaccattttacaagaaca
acaacatggcagaggccaacactggaatctgtccgcaactatgaacaatggcagctacaa
cgtagccaacttcaaggagcaatgcagcagtttaatcagagatttatttatgggaatcaa
gatttgtttgctacatcacaaaataaagaatttgatccgcttggtcctttgccacctggg
tgggagaagagaactgataacaatggcagagtatattttgtcaaccacaacactcgaatt
actcaatgggaagacccccgaagtcaaggtcaattaaatgaaaagcccctacctgaaggc
tgggaaatgagatttacagtggatgggattccatattttgtggaccacaatagaagaaca
acaacctacatagatccccgaacaggaaaatctgccttagacaatggaccccagatagcc
tatgttcgagacttcaaagcaaaggttcagtacttccggttttggtgtcagcaactggcc
atgccacagcacataaagattacagtgacaagaaaaacattgtttgaagattcctttcag
cagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgatttttccagga
gaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtcacatgaa
gtgttgaaccccatgtattgcctgtttgaatatgcagggaaggataactactgcttgcag
ataaaccctgcatcttacatcaatcctgatcatctgaaatattttcgctttattggcagg
tttattgccatggctctattccatggaaaattcatagacacgggtttttccttaccattc
tataaacgtatcttgaacaaaccagttggacttaaagatttagaatctattgatccagaa
ttttacaattctctcatctgggttaaagagaacaatattgaagaatgtggcttggaaatg
tacttctctgtggataaagaaattttaggtgaaattaagagccatgatttgaaacccaat
ggtggcaatattcttgtgacagaagaaaataaagaggaatatataagaatggtggctgaa
tggaggttgtctcgaggagttgaagaacagacacaagctttctttgagggctttaatgaa
attcttccccagcagtatttgcaatacttcgatgcaaaggaattagaggtacttttatgt
ggaatgcaagagattgatttgaatgactggcaaagacatgctatctaccgtcattacact
aggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataatgagaag
agaatgagacttctgcaatttgttactggaacttgccgattgccagtaggaggatttgct
gacctcatggggagcaatgggccacagaaattctgcattgaaaaagttgggaaagaaaat
tggctacccagaagtcatacctgttttaatcgcctggaccttccaccctataagagctat
gagcaactgaaggagaagctgttgtttgccattgaagaaacagaaggatttggacaagag
taa
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