Dipodomys merriami (Merriam's kangaroo rat): 138830896
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Entry
138830896 CDS
T11079
Symbol
Brca1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer01524
Platinum drug resistance
dmer03440
Homologous recombination
dmer03460
Fanconi anemia pathway
dmer04120
Ubiquitin mediated proteolysis
dmer04151
PI3K-Akt signaling pathway
dmer05206
MicroRNAs in cancer
dmer05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
138830896 (Brca1)
09124 Replication and repair
03440 Homologous recombination
138830896 (Brca1)
03460 Fanconi anemia pathway
138830896 (Brca1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
138830896 (Brca1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
138830896 (Brca1)
09162 Cancer: specific types
05224 Breast cancer
138830896 (Brca1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
138830896 (Brca1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
dmer01009
]
138830896 (Brca1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
dmer04121
]
138830896 (Brca1)
03036 Chromosome and associated proteins [BR:
dmer03036
]
138830896 (Brca1)
03400 DNA repair and recombination proteins [BR:
dmer03400
]
138830896 (Brca1)
Enzymes [BR:
dmer01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
138830896 (Brca1)
Protein phosphatases and associated proteins [BR:
dmer01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
138830896 (Brca1)
Ubiquitin system [BR:
dmer04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
138830896 (Brca1)
Multi subunit type E3
BRCC complex
138830896 (Brca1)
Chromosome and associated proteins [BR:
dmer03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
138830896 (Brca1)
DNA repair and recombination proteins [BR:
dmer03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
138830896 (Brca1)
BRCA1-A complex
138830896 (Brca1)
BRCA1-B complex
138830896 (Brca1)
BRCA1-C complex
138830896 (Brca1)
BRCA complex
138830896 (Brca1)
FA (Fanconi anemia) pathway
Downstream FA components
138830896 (Brca1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-C3HC4_4
zf-RING_UBOX
zf-RING_2
zf-C3HC4_3
RING_XB3-XBAT31
zf-RING_5
zf-Nse
zf-RING_6
BRCT_2
zf-ANAPC11
zf-RING_10
RTT107_BRCT_5
Med15_fungi
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
138830896
NCBI-ProteinID:
XP_069883885
LinkDB
All DBs
Position
Unknown
AA seq
1800 aa
AA seq
DB search
MDSSLAQIEEVQHVLNAMQKILECPICLELIKEPVSTKCDHIFCRFCMLKLLNQKKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLGIIHAFELDTGLQFANVNYTFSKKNKSPEHLEE
EISVIQSLGYRDRAKKFRQNESQNSTLQDVSLSVQLSKLGIVSSLKTKKQIQPQNKSVYI
ELGSDSSEETSYISNYCSVRDEELLQITPQGTSAEASLDSSKRASCEEDITNIGHQSTSN
DSNTIGKQATERHPEKNQSISVSNLHEEPCGTNTHASSLQHENSSLLLTKDRMDVEKAAF
CNKSKQPALARSQQSRWIERKETCHDRQIPSAETKVDLNADPGCGCKECSENPRSTQDVP
WITLNSSIQKVNDWLTRSDDMLTSDDSGKSETNDEVDGTLEVPHEVDGYSGPSKKINLLA
TDPHTSLESKSLKIVSSNMEDKIFGKTYRRRTSLPNLNHVPENLIRIALPTEPKIQEQPL
TNKLKRKRRATSCLQPEDFIKTADMTLVQKTPEKVNQETHQMEQNGQEMSLTKSGHENEI
KSDYVQKEKNVNPEESLGEESKAESIRSSINTMEVGLNIHSPKLPKKNRLRRKPPIRHLH
APDVVFRALSPPNPSELQINSCTSSEETKKSSSQTSDRCGRTLQSLEDTQSTTGAKKSNK
LDEQISKICDSDVSSEPKLTNTPAGFTNCSSSNKLEESVGPSLEREEIEENLETIEVPNL
TKDPRDQLVNGERAIPTELSADSTNLSWTPDSESDTQDSISLLEINPLRRGKTASNQCVI
QYEAVGNPNHIIHDCSKTTRHDTEGFMDPLRQEGSHMLESDIETEESELDTQYLQNTFQD
SKRQSFALFSNSGNPEKECATVSAHSMSLSKQSPNVILEYKQRENHQDKESKTRLAQAVK
ATMDFPVICQKHEPGDNAECSSSIAKTSGLCPSSQLTANELTSANKLRILQNSYLIPSIS
PVRPSVKTKCKKSLLKQMFEKQSMSSEEGLESESIIQSTLCMFSPNNIETAFKGASPGSI
NEVGSSTTGGGSSINEVASSVENIQEELNRSRGPELNAVLRLGHTQPEAYNQTLPASSCK
HPEIKEQTENEGVVQAVGADFSPCLISDTLETGMTSNDVSQICPETPEDLLYNDEIKENT
SFTEGAIEETSAVFSKSIQKREFSQSLSPSLTPPSLAQGLEIDDDLPGFRHFLFSKVTNT
LSQSIRHTIKCLSQETEENPVSLRNSLQVNNNEILVEASQETQCSNNTGPSHHGALVDLT
TNSNSQDSFLMFSSPKQMNQEVIVLSDRGLVSDDEEREPDLEEEERTDSNLGEAASGYDS
ETNLSENISEVSSQNDFLTSQQKHIMKDNLKKIQQEMAHLEAVLQQHKSQQLPASSTSLL
ANYCGPEQNISGKAVLTPEKNNGHPVSQTRKAFSADEFQVSPDSSTSKNKELGVERTSPS
KTQLVGSSGSVHYLSTRLQNRNFPSQRELVVIDLEEEQLEKSQPPDLMEQSYLPKQDLER
IPDLQSGNCLFYNEPKSEPPKDSTLEPAHVCSLSSQFQVAQSASSPAAAHGDKAREEREK
RDKPELKTSTAKVNKRMSMVVSGLIQKEFVLAQKFARKHHITLTNAVTEETTHVVMKTDA
ELVCERTLKYFLGIAGRKWVVSYFWVTQSIKEGKVLDEHDFEVRGDVINGRNHQGPKRAR
ESQEKLFTGLEICCYGPFTNMAIDQLEWVLQLCGASVVKELSSITVGTRSPLIVVIQPDA
WTEDSSFQAISQLCEASVVTREWVLDSVALYKRQDLGTYLITQIPYSEDGSQPQIKTTGP
NT seq
5403 nt
NT seq
+upstream
nt +downstream
nt
atggattcgtctttagctcaaattgaagaagtacagcatgtccttaatgctatgcagaaa
atcttagagtgtccaatatgtctggaattaatcaaagaacctgtttccacaaagtgtgac
cacatattttgcagattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatgatattaccaaaaggagtctacaagaaagtacaagatttagt
caacttgttgaagagctattgggaatcattcatgcttttgaacttgacacaggattgcag
tttgcaaatgtgaattataccttttcaaagaagaataagtctcctgaacatttagaggaa
gagatttctgtcatccaaagtttgggctaccgagaccgtgccaaaaagtttcgacagaat
gaatctcagaattctacattgcaggacgtcagtcttagtgtccagctctctaaacttggg
attgtgagctctctgaagacaaagaagcagatacagcctcaaaataaatctgtctacatt
gaattgggatctgattcatctgaagaaacaagttatatatcaaattattgcagtgtaaga
gatgaagaattgttacaaatcactcctcaaggaactagtgctgaagccagtttggattct
tcaaaaagagcttcctgtgaggaggacataacaaatattggacatcaatccactagtaac
gattcaaacactattgggaaacaggccactgagaggcatccagaaaagaatcagagcatt
tctgtttcaaacttgcatgaggagccatgtggcacaaatactcatgccagctcattacag
catgagaacagtagtttattactcactaaagacagaatggatgtagaaaaggctgcattc
tgtaataaaagcaaacagcctgccttagcaaggagccaacagagcagatggattgaacgt
aaggaaacgtgtcatgataggcagattcccagtgcagagacaaaggtagatctgaatgct
gatcccggctgtgggtgtaaagaatgttctgagaatccaagaagtacccaagatgttccc
tggataactctaaatagcagcattcagaaagttaatgactggcttaccagaagtgatgat
atgctaacttctgatgacagtgggaagtctgaaacaaatgatgaagtagatggtacctta
gaagttccacatgaagtagatggatattctggtccttcaaagaaaataaacttactggcc
actgatcctcatacttctttagagagtaaaagcctcaaaatagtttcaagtaatatggaa
gataagatatttggtaaaacctatcggaggaggacaagcctccctaatttgaaccatgta
cctgaaaatctaataagaatagcacttcctacagaaccaaagatacaggagcaacctctc
acaaataaactaaagcgtaaaaggagagctacatcatgcctgcaacctgaggattttatt
aagacagcagatatgacacttgttcaaaagactcctgaaaaggtaaatcaggaaacgcac
caaatggagcaaaatggtcaggagatgagtctgactaaaagtggtcatgagaatgaaata
aaaagtgactatgttcagaaagagaaaaatgtgaatccagaagaatcgttgggagaagag
tctaaagctgaatcaataaggagcagtataaacactatggaagtaggattaaatatccac
agtccaaaactacctaagaaaaataggctgaggagaaagccccctatcagacatcttcat
gcacctgacgtagtattcagagctctaagcccacctaatcctagtgaactacaaattaac
agttgtacaagcagtgaggagacaaaaaaaagttccagtcaaacatcagataggtgtggc
agaacacttcaatccctagaagacacacagtctacaactggagccaaaaagagtaacaag
ctagatgaacaaataagtaagatatgtgacagtgatgtttcctcagaaccgaagttaaca
aacacacctgctggttttactaactgctcaagttctaataaacttgaagaatctgtcgga
cctagccttgagagagaagaaatagaagagaacctagaaacaatagaagtgccaaatctt
accaaagaccccagagatcagttggtaaatggagaaagggcaattccaactgaattatct
gcagatagtaccaatctttcatggacacctgattctgaatctgacacccaggacagtatc
tcattactagaaattaacccccttagaagggggaaaacagcatcaaatcaatgtgtgatt
cagtatgaagcagttggaaaccccaaccacattatccatgattgttctaaaactactaga
cacgacacagaaggcttcatggatccattgagacaggaaggtagccacatgctggagagt
gatatagaaacagaagagagtgaacttgatacccagtatctgcagaacacattccaagat
tcaaagcgtcagtcatttgctctgttttcaaattcaggaaatccagaaaaggaatgtgcc
acagtctctgcccactctatgtccttaagtaagcaaagtccaaatgtcattcttgaatat
aaacaaagagaaaaccatcaggacaaagagtctaaaaccaggcttgcacaggcagtcaag
gccactatggatttccctgtgatttgtcagaagcatgagccaggggataatgctgaatgt
agtagtagcattgcaaaaacctctgggctttgtccatcatctcagttaaccgccaatgaa
ctaacttctgccaataaacttagaattttacagaattcatatcttataccatcaatttct
ccagtcaggccatctgttaaaactaaatgtaagaaaagcctgttaaagcaaatgtttgag
aaacagtcaatgtcatctgaagaaggattggaaagtgagagcattattcaaagtacactg
tgcatgtttagcccaaataacatagaaactgcttttaaaggagccagcccaggcagtatt
aatgaagtaggctccagtactactggaggaggctccagtattaacgaagtagcttctagt
gttgaaaacattcaagaagaactaaacagaagccgagggcctgaactaaatgctgtgcta
cgattaggtcatacgcaacctgaagcctataaccaaactctccctgcaagtagttgtaag
catcctgaaataaaagaacaaacagaaaatgaaggagtagttcaggctgttggtgcagat
ttttctccatgtctaatttcagataccctagaaacaggtatgacaagtaatgatgtctct
cagatttgtcctgagacacctgaggatctgttatataatgatgaaataaaggaaaatacc
agctttactgaaggtgccattgaggaaacatctgctgtttttagcaaaagtattcagaaa
agagagttcagccagagccttagcccttctttaacccctccatctttggctcaaggtctt
gaaatagatgatgatcttcccggcttccgacacttcttatttagtaaagtaaccaataca
ctatctcagtctatcagacatacaataaagtgtctgtctcaggaaacagaggagaaccca
gtatcactgaggaatagcttacaagtcaacaataatgagatcttagtggaagcatcccag
gagacacagtgctctaacaatacagggccttcacatcatggtgcattggtagacctgact
acaaactccaactcccaagattccttcttgatgttttcttctcccaaacaaatgaaccag
gaagttattgttctgagtgacagaggattggtttcagatgatgaagaaagggaacctgac
ctggaagaagaggaaagaacggattcaaacttaggtgaagcagcatctggctatgacagt
gaaacaaacctttctgaaaatatctcagaagtgtcctcacagaatgattttttaacctct
cagcagaagcatattatgaaagataacctgaaaaagatccagcaggaaatggcccatcta
gaagctgtgctacagcagcacaagagccagcaacttcctgccagctccacttccctccta
gctaactattgtggaccagaacaaaacatatcaggaaaagcagttttaactccagagaaa
aataatggacatcctgtaagccaaactcgaaaagccttttctgctgatgagttccaagta
tctccagatagttccaccagtaaaaataaagaactaggagtggaaaggacttccccatca
aagacccagttggttggtagtagtgggtctgtgcactacctgtctaccaggcttcagaat
agaaacttcccatctcaaagggagcttgtggtgattgatctggaggaggaacagctggag
aagtctcagccacctgacttaatggagcagtcttatttgccaaagcaggacctagagaga
atccctgatctgcagtctggaaactgcctcttctacaatgagcctaaatctgaaccccct
aaagacagcactctagagccagctcatgtctgcagtttatcatcccaatttcaagttgcc
cagtctgccagcagtccagccgctgctcatggggacaaagcaagggaagagagagagaag
agagacaaaccagaattgaagacttcaacagcaaaggtcaacaaaagaatgtctatggtg
gtatcaggcttgatccaaaaagaatttgtacttgcacagaagtttgccagaaaacaccac
atcactttaactaacgcagttactgaagagactacgcatgtcgttatgaaaacagatgct
gagttggtttgtgaacggacactgaaatattttctgggaattgcaggaagaaaatgggta
gttagctatttctgggtgacccagtctattaaagaaggaaaggtgctggatgagcatgat
tttgaagtcagaggtgatgtgatcaatggaagaaaccaccaaggaccaaagagagcgagg
gaatcacaggagaagcttttcacaggcctagaaatctgttgctatgggccctttaccaac
atggccatagatcaactggagtgggtactgcagctgtgtggggcctcagtagtaaaggag
ctttcatcaatcaccgtgggcacacgctctcccctaattgtggtcatacagccagatgcc
tggacagaagacagtagcttccaggccatcagtcagttgtgtgaagcatccgtggtgacc
cgggagtgggtattggacagtgtggccctctacaagcgccaggatttgggcacctacctg
ataacacaaatcccctacagtgaagatggcagccagccacagatcaaaaccacagggccc
taa
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